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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+19.22%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$420M
AUM Growth
+$109M
Cap. Flow
+$37.3M
Cap. Flow %
8.9%
Top 10 Hldgs %
50.94%
Holding
96
New
34
Increased
16
Reduced
15
Closed
28

Top Buys

Rank Stock Value
1
MRK icon
Merck
MRK
+$14.6M
2
GILD icon
Gilead Sciences
GILD
+$12.1M
3
GSK icon
GSK
GSK
+$9.11M
4
SNY icon
Sanofi
SNY
+$8.01M
5
MDT icon
Medtronic
MDT
+$7.28M

Top Sells

Rank Stock Value
1
JNJ icon
Johnson & Johnson
JNJ
+$18.6M
2
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$8.58M
3
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$7.52M
4
AVTR icon
Avantor
AVTR
+$6.99M
5
INMD icon
InMode
INMD
+$5.79M

Sector Composition

Rank Sector Weight
1 Healthcare 72.48%
2 Financials 0.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DVAX
76
DELISTED
Dynavax Technologies
DVAX
– –
-465,299
Closed -$1.66M
GKOS icon
77
PUT
Glaukos
GKOS
$9.83B
– –
-51,800
Closed -$3.24M
HSIC icon
78
PUT
Henry Schein
HSIC
$9.77B
– –
-65,000
Closed -$4.13M
ICLR icon
79
Icon
ICLR
$12.6B
– –
-20,530
Closed -$3.02M
INMD icon
80
InMode
INMD
$870M
– –
-538,766
Closed -$5.79M
JNJ icon
81
Johnson & Johnson
JNJ
$618B
– –
-143,707
Closed -$18.6M
LXRX icon
82
Lexicon Pharmaceuticals
LXRX
$1.03B
– –
-20,667
Closed -$62K
NVO
83
Novo Nordisk
NVO
$208B
– –
-158,200
Closed -$4.09M
OPK icon
84
CALL
Opko Health
OPK
$985M
– –
-125,300
Closed -$262K
PINC
85
DELISTED
Premier
PINC
– –
-68,597
Closed -$1.98M
WST icon
86
PUT
West Pharmaceutical
WST
$24B
– –
-5,000
Closed -$709K
XGN icon
87
Exagen
XGN
$109M
– –
-85,000
Closed -$1.32M
XRAY icon
88
PUT
Dentsply Sirona
XRAY
$2.68B
– –
-50,000
Closed -$2.67M
MRTX
89
DELISTED
Mirati Therapeutics, Inc. Common Stock
MRTX
– –
-96,525
Closed -$7.52M
SPPI
90
DELISTED
Spectrum Pharmaceuticals Inc
SPPI
– –
-619,019
Closed -$5M
HTGM
91
DELISTED
HTG Molecular Diagnostics, Inc. Common Stock
HTGM
– –
-1,667
Closed -$199K
CERN
92
PUT
DELISTED
Cerner Corp
CERN
– –
-62,300
Closed -$4.25M
DRNA
93
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
– –
-369,494
Closed -$5.31M
VAR
94
PUT
DELISTED
Varian Medical Systems, Inc.
VAR
– –
-4,400
Closed -$524K
FOMX
95
DELISTED
Foamix Pharmaceuticals Ltd. Ordinary Shares
FOMX
– –
-920,796
Closed -$2.8M
HSACU
96
DELISTED
Health Sciences Acquisitions Corporation Units
HSACU
– –
-307,000
Closed -$3.29M
1 2 3
4

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Sio Capital Management's Q4 2019 Portfolio in Review

As of Q4 2019, Sio Capital Management held 96 positions worth $420M, up 35% from $310M the previous quarter. Its ten largest holdings account for 51% of the portfolio.

Sio Capital Management deployed $37.3M of net new capital in Q4 2019, opening 34 new positions and adding to 16 existing holdings. Its largest new stake was Merck: 177,903 shares worth $15.4M.

By sector, the portfolio is most concentrated in Healthcare at 72% of assets, down from 82% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Alnylam Pharmaceuticals, an estimated $8.58M trimmed.

  • Sio Capital Management's largest Q4 2019 buy was Merck: 177,903 shares worth $15.4M.
  • Sio Capital Management added most to Medtronic in Q4 2019, an estimated $7.28M increase.
  • Sio Capital Management's biggest Q4 2019 reduction was Alnylam Pharmaceuticals, cutting an estimated $8.58M.
  • Sio Capital Management fully exited Johnson & Johnson in Q4 2019, selling an estimated $18.6M.
  • Sio Capital Management's ten largest holdings make up 51% of its $420M portfolio in Q4 2019.
  • Sio Capital Management opened 34 new positions and closed 28 in Q4 2019.
  • Sio Capital Management's portfolio value rose 35% quarter-over-quarter to $420M.

Based on Sio Capital Management's 13F filing for Q4 2019, filed 14 Feb 2020.