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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+54.77%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$439M
AUM Growth
+$116M
Cap. Flow
+$43.2M
Cap. Flow %
9.83%
Top 10 Hldgs %
76.24%
Holding
61
New
9
Increased
9
Reduced
7
Closed
18

Top Buys

Rank Stock Value
1
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$81.6M
2
CI icon
Cigna
CI
+$17M
3
GRCL
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
+$13.3M
4
IMGN
Immunogen Inc
IMGN
+$8.2M
5
PTGX icon
Protagonist Therapeutics
PTGX
+$3.71M

Top Sells

Rank Stock Value
1
GEHC icon
GE HealthCare
GEHC
+$16.5M
2
BCYC
Bicycle Therapeutics
BCYC
+$16M
3
PFE icon
Pfizer
PFE
+$14.9M
4
OGN icon
Organon & Co
OGN
+$13.3M
5
REGN icon
Regeneron Pharmaceuticals
REGN
+$12.6M

Sector Composition

Rank Sector Weight
1 Healthcare 88.39%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
OGN icon
51
Organon & Co
OGN
$3.56B
– –
-767,000
Closed -$13.3M
PFE icon
52
Pfizer
PFE
$147B
– –
-450,700
Closed -$14.9M
REGN icon
53
Regeneron Pharmaceuticals
REGN
$79.1B
– –
-15,250
Closed -$12.6M
RPTX
54
DELISTED
Repare Therapeutics
RPTX
– –
-76,049
Closed -$919K
RVMD icon
55
Revolution Medicines
RVMD
$41.9B
– –
-72,700
Closed -$2.01M
SGHT icon
56
Sight Sciences
SGHT
$302M
– –
-246,699
Closed -$831K
SVRA icon
57
Savara
SVRA
$1.13B
– –
-896,250
Closed -$3.39M
TVTX icon
58
Travere Therapeutics
TVTX
$5.84B
– –
-884,770
Closed -$7.91M
VKTX icon
59
Viking Therapeutics
VKTX
$3.91B
– –
-595,002
Closed -$6.59M
RVNC
60
DELISTED
Revance Therapeutics, Inc.
RVNC
– –
-342,477
Closed -$3.93M
KRTX
61
DELISTED
Karuna Therapeutics, Inc. Common Stock
KRTX
– –
-24,129
Closed -$4.08M
1 2
3

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Sio Capital Management's Q4 2023 Portfolio in Review

As of Q4 2023, Sio Capital Management held 61 positions worth $439M, up 36% from $323M the previous quarter. Its ten largest holdings account for 76% of the portfolio.

Sio Capital Management deployed $43.2M of net new capital in Q4 2023, opening 9 new positions and adding to 9 existing holdings. Its largest new stake was Mirati Therapeutics, Inc. Common Stock: 1,451,925 shares worth $85.3M.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, down from 100% a quarter earlier.

On the sell side, the largest reduction was Teleflex, an estimated $5.98M trimmed.

  • Sio Capital Management's largest Q4 2023 buy was Mirati Therapeutics, Inc. Common Stock: 1,451,925 shares worth $85.3M.
  • Sio Capital Management added most to Cigna in Q4 2023, an estimated $17M increase.
  • Sio Capital Management's biggest Q4 2023 reduction was Teleflex, cutting an estimated $5.98M.
  • Sio Capital Management fully exited GE HealthCare in Q4 2023, selling an estimated $16.5M.
  • Sio Capital Management's ten largest holdings make up 76% of its $439M portfolio in Q4 2023.
  • Sio Capital Management opened 9 new positions and closed 18 in Q4 2023.
  • Sio Capital Management's portfolio value rose 36% quarter-over-quarter to $439M.

Based on Sio Capital Management's 13F filing for Q4 2023, filed 13 Feb 2024.