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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
-7.3%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$314M
AUM Growth
-$88.6M
Cap. Flow
-$54.8M
Cap. Flow %
-17.46%
Top 10 Hldgs %
50.02%
Holding
85
New
12
Increased
22
Reduced
16
Closed
24

Top Buys

Rank Stock Value
1
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$13.3M
2
CI icon
Cigna
CI
+$11.1M
3
MRK icon
Merck
MRK
+$9.51M
4
CAH icon
Cardinal Health
CAH
+$5.84M
5
RCOR
Renovacor, Inc.
RCOR
+$5.23M

Top Sells

Rank Stock Value
1
HRC
HILL-ROM HOLDINGS, INC.
HRC
+$8.71M
2
AMGN icon
Amgen
AMGN
+$8.53M
3
AFMD
Affimed
AFMD
+$6.07M
4
CHRS icon
Coherus Oncology
CHRS
+$5.72M
5
SYNH
Syneos Health, Inc. Class A Common Stock
SYNH
+$5.6M

Sector Composition

Rank Sector Weight
1 Healthcare 87.44%
2 Consumer Staples 2.92%
3 Industrials 0.71%
4 Financials 0.56%
5 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LITS
51
Lite Strategy Inc
LITS
$33M
$1.18M 0.37%
21,302
– –
NTUS
52
DELISTED
Natus Medical Inc
NTUS
$987K 0.31%
+39,354
New +$1M
LOGC
53
DELISTED
LogicBio Therapeutics, Inc. Common Stock
LOGC
$836K 0.27%
182,630
– –
ARDX icon
54
Ardelyx
ARDX
$1.21B
$755K 0.24%
572,082
+46,086
+9% +$123K
NYXH
55
Nyxoah
NYXH
$142M
$477K 0.15%
+16,310
New +$516K
CMAX
56
DELISTED
CareMax, Inc. Class A Common Stock
CMAX
$297K 0.09%
1,025
-427
-29% -$126K
NGNE icon
57
Neurogene
NGNE
$709M
$277K 0.09%
1,916
– –
RCOR.WS
58
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$274K 0.09%
+400,000
New +$312K
HUMAW icon
59
Humacyte Inc Warrant
HUMAW
$1.09M
$145K 0.05%
+49,998
New +$146K
RUBY
60
DELISTED
Rubius Therapeutics, Inc
RUBY
$111K 0.04%
6,200
– –
CMAXW
61
DELISTED
CareMax, Inc. Warrant
CMAXW
$36K 0.01%
+12,808
New +$37.2K
AFMD
62
DELISTED
Affimed
AFMD
– –
-71,458
Closed -$6.07M
AMGN icon
63
Amgen
AMGN
$218B
– –
-35,000
Closed -$8.53M
AMN icon
64
AMN Healthcare
AMN
$1.27B
– –
-26,001
Closed -$2.52M
EFOR
65
Everforth Inc
EFOR
$1.25B
– –
-36,692
Closed -$3.56M
ASND icon
66
PUT
Ascendis Pharma A/S
ASND
$16.1B
– –
-251,900
Closed -$33.1M
AUTL
67
Autolus Therapeutics
AUTL
$500M
– –
-591,870
Closed -$3.93M
CHRS icon
68
Coherus Oncology
CHRS
$228M
– –
-413,733
Closed -$5.72M
CVRX icon
69
CVRx
CVRX
$146M
– –
-15,000
Closed -$420K
EPIX
70
DELISTED
ESSA Pharma
EPIX
– –
-148,127
Closed -$4.23M
FULC icon
71
Fulcrum Therapeutics
FULC
$288M
– –
-77,477
Closed -$812K
GOSS icon
72
Gossamer Bio
GOSS
$87.8M
– –
-261,400
Closed -$2.12M
IDYA icon
73
IDEAYA Biosciences
IDYA
$3.51B
– –
-48,298
Closed -$1.01M
MESO
74
PUT
Mesoblast
MESO
$1.94B
– –
-27,400
Closed -$410K
MGNX icon
75
MacroGenics
MGNX
$250M
– –
-112,587
Closed -$3.02M
1 2
3
4

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WIC
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AAM
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Sio Capital Management's Q3 2021 Portfolio in Review

As of Q3 2021, Sio Capital Management held 85 positions worth $314M, down 22% from $402M the previous quarter. Its ten largest holdings account for 50% of the portfolio.

Sio Capital Management withdrew a net $54.8M in Q3 2021, closing 24 positions and reducing 16 holdings. Its most notable exit was HILL-ROM HOLDINGS, INC., an estimated $8.71M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, up from 79% a quarter earlier, followed by Consumer Staples and Industrials.

Against the trend, Sio Capital Management opened a new position in Lakefront Biotherapeutics American Depositary Shares worth $11.8M.

  • Sio Capital Management's largest Q3 2021 buy was Lakefront Biotherapeutics American Depositary Shares: 224,719 shares worth $11.8M.
  • Sio Capital Management added most to Cigna in Q3 2021, an estimated $11.1M increase.
  • Sio Capital Management's biggest Q3 2021 reduction was Horizon Therapeutics Public Limited Company Ordinary Shares, cutting an estimated $3.96M.
  • Sio Capital Management fully exited HILL-ROM HOLDINGS, INC. in Q3 2021, selling an estimated $8.71M.
  • Sio Capital Management's ten largest holdings make up 50% of its $314M portfolio in Q3 2021.
  • Sio Capital Management opened 12 new positions and closed 24 in Q3 2021.
  • Sio Capital Management's portfolio value fell 22% quarter-over-quarter to $314M.

Based on Sio Capital Management's 13F filing for Q3 2021, filed 15 Nov 2021.