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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+16.75%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$226M
AUM Growth
+$79.9M
Cap. Flow
+$76M
Cap. Flow %
33.66%
Top 10 Hldgs %
58.47%
Holding
54
New
20
Increased
12
Reduced
7
Closed
12

Top Buys

Rank Stock Value
1
DYAX
DYAX CORPORATION
DYAX
+$22.1M
2
MTEM
Molecular Templates, Inc.
MTEM
+$12M
3
SNY icon
Sanofi
SNY
+$10.6M
4
MCK icon
McKesson
MCK
+$10.6M
5
AAAP
Advanced Accelerator Applications S.A.
AAAP
+$8.11M

Top Sells

Rank Stock Value
1
JNJ icon
Johnson & Johnson
JNJ
+$7.98M
2
CAH icon
Cardinal Health
CAH
+$7.29M
3
MDT icon
Medtronic
MDT
+$5.89M
4
AMGN icon
Amgen
AMGN
+$5.23M
5
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$5.22M

Sector Composition

Rank Sector Weight
1 Healthcare 78%
2 Financials 2.43%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ACHN
51
DELISTED
Achillion Pharmaceuticals
ACHN
– –
-364,368
Closed -$2.52M
CXRX
52
DELISTED
Concordia International Corp. Common Stock
CXRX
– –
-5,201
Closed -$221K
BSTG
53
DELISTED
Biostage, Inc. Common Stock
BSTG
– –
-116,593
Closed -$99K
CYBX
54
DELISTED
CYBERONICS INC
CYBX
– –
-40,478
Closed -$2.46M
1 2
3

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Sio Capital Management's Q4 2015 Portfolio in Review

As of Q4 2015, Sio Capital Management held 54 positions worth $226M, up 55% from $146M the previous quarter. Its ten largest holdings account for 58% of the portfolio.

Sio Capital Management deployed $76M of net new capital in Q4 2015, opening 20 new positions and adding to 12 existing holdings. Its largest new stake was DYAX CORPORATION: 687,600 shares worth $25.9M.

By sector, the portfolio is most concentrated in Healthcare at 78% of assets, down from 96% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Medtronic, an estimated $5.89M trimmed.

  • Sio Capital Management's largest Q4 2015 buy was DYAX CORPORATION: 687,600 shares worth $25.9M.
  • Sio Capital Management added most to Sanofi in Q4 2015, an estimated $10.6M increase.
  • Sio Capital Management's biggest Q4 2015 reduction was Medtronic, cutting an estimated $5.89M.
  • Sio Capital Management fully exited Johnson & Johnson in Q4 2015, selling an estimated $7.98M.
  • Sio Capital Management's ten largest holdings make up 58% of its $226M portfolio in Q4 2015.
  • Sio Capital Management opened 20 new positions and closed 12 in Q4 2015.
  • Sio Capital Management's portfolio value rose 55% quarter-over-quarter to $226M.

Based on Sio Capital Management's 13F filing for Q4 2015, filed 16 Feb 2016.