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Sio Capital Management Portfolio holdings

AUM $697M
1-Year Est. Return 79.73%
This Fund
S&P 500
This Quarter Est. Return
+14.43%
1 Year Est. Return
+79.73%
3 Year Est. Return
+576.62%
5 Year Est. Return
+422.76%
10 Year Est. Return
+2,506.65%
AUM
$166M
AUM Growth
-$10.9M
Cap. Flow
-$8.15M
Cap. Flow %
-4.9%
Top 10 Hldgs %
65.79%
Holding
63
New
18
Increased
12
Reduced
1
Closed
32

Top Buys

Rank Stock Value
1
GYRE icon
Gyre Therapeutics
GYRE
+$23.6M
2
SNY icon
Sanofi
SNY
+$17M
3
BIIB icon
Biogen
BIIB
+$9.9M
4
MRK icon
Merck
MRK
+$6.5M
5
KURA icon
Kura Oncology
KURA
+$5.17M

Top Sells

Rank Stock Value
1
GSK icon
GSK
GSK
+$11.6M
2
QTNT
Quotient Limited Ordinary Shares
QTNT
+$7.06M
3
AET
Aetna Inc
AET
+$4.75M
4
EBS icon
Emergent Biosolutions
EBS
+$4.25M
5
RIGL icon
Rigel Pharmaceuticals
RIGL
+$3.43M

Sector Composition

Rank Sector Weight
1 Healthcare 85.74%
2 Financials 3.21%
3 Technology 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DERM
26
DELISTED
Dermira, Inc.
DERM
$1.52M 0.91%
+190,300
New +$4.14M
EPZM
27
DELISTED
Epizyme, Inc
EPZM
$1.29M 0.78%
+72,826
New +$1.23M
HRTX icon
28
PUT
Heron Therapeutics
HRTX
$93.9M
$814K 0.49%
+29,500
New +$669K
CRIS icon
29
Curis
CRIS
$9.78M
$545K 0.33%
+417
New +$546K
AXSM icon
30
Axsome Therapeutics
AXSM
$11.2B
$474K 0.28%
+193,290
New +$579K
ATNM icon
31
Actinium Pharmaceuticals
ATNM
$26.3M
$393K 0.24%
+35,873
New +$610K
EFOR
32
CALL
Everforth Inc
EFOR
$1.17B
– –
-77,000
Closed -$4.95M
CAH icon
33
CALL
Cardinal Health
CAH
$53.9B
– –
-80,000
Closed -$4.9M
EBS icon
34
Emergent Biosolutions
EBS
$373M
– –
-91,533
Closed -$4.25M
GSK icon
35
GSK
GSK
$104B
– –
-260,658
Closed -$11.6M
HCA icon
36
CALL
HCA Healthcare
HCA
$87.2B
– –
-42,100
Closed -$3.7M
ISRG icon
37
Intuitive Surgical
ISRG
$127B
– –
-9,000
Closed -$1.09M
ISRG icon
38
PUT
Intuitive Surgical
ISRG
$127B
– –
-48,000
Closed -$5.84M
LGND icon
39
CALL
Ligand Pharmaceuticals
LGND
$5.76B
– –
-28,854
Closed -$2.46M
MD icon
40
Pediatrix Medical
MD
$2.18B
– –
-56,598
Closed -$3.02M
PBYI icon
41
Puma Biotechnology
PBYI
$404M
– –
-12,209
Closed -$1.21M
PFE icon
42
PUT
Pfizer
PFE
$143B
– –
-105,400
Closed -$3.62M
PINC
43
CALL
DELISTED
Premier
PINC
– –
-160,000
Closed -$4.67M
RIGL icon
44
Rigel Pharmaceuticals
RIGL
$681M
– –
-88,506
Closed -$3.43M
SAGE
45
PUT
DELISTED
Sage Therapeutics
SAGE
– –
-179,200
Closed -$29.5M
TNET icon
46
CALL
TriNet
TNET
$3.02B
– –
-110,000
Closed -$4.88M
UNH icon
47
CALL
UnitedHealth
UNH
$376B
– –
-20,000
Closed -$4.41M
VRTX icon
48
Vertex Pharmaceuticals
VRTX
$121B
– –
-14,874
Closed -$2.23M
XNCR icon
49
Xencor
XNCR
$1.5B
– –
-109,981
Closed -$2.41M
NXGN
50
PUT
DELISTED
NextGen Healthcare, Inc. Common Stock
NXGN
– –
-18,200
Closed -$247K
1
2
3

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Sio Capital Management's Q1 2018 Portfolio in Review

As of Q1 2018, Sio Capital Management held 63 positions worth $166M, down 6.1% from $177M the previous quarter. Its ten largest holdings account for 66% of the portfolio.

Sio Capital Management withdrew a net $8.15M in Q1 2018, closing 32 positions and reducing 1 holding. Its most notable exit was GSK, an estimated $11.6M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 86% of assets, up from 49% a quarter earlier, followed by Financials and Technology.

Against the trend, Sio Capital Management opened a new position in Sanofi worth $16.4M.

  • Sio Capital Management's largest Q1 2018 buy was Sanofi: 408,621 shares worth $16.4M.
  • Sio Capital Management added most to Gyre Therapeutics in Q1 2018, an estimated $23.6M increase.
  • Sio Capital Management's biggest Q1 2018 reduction was Aetna Inc, cutting an estimated $4.75M.
  • Sio Capital Management fully exited GSK in Q1 2018, selling an estimated $11.6M.
  • Sio Capital Management's ten largest holdings make up 66% of its $166M portfolio in Q1 2018.
  • Sio Capital Management opened 18 new positions and closed 32 in Q1 2018.
  • Sio Capital Management's portfolio value fell 6.1% quarter-over-quarter to $166M.

Based on Sio Capital Management's 13F filing for Q1 2018, filed 15 May 2018.