Simplex Trading
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Simplex Trading’s Protagonist Therapeutics PTGX Stock Holding History

Simplex Trading’s Portfolio PTGX Stock Details PTGX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$3.71M Buy
+35,200
New +$3.12M ﹤0.01% 1334
2025
Q4 		– Sell
-15,700
Closed -$1.04M – 9777
2025
Q3 		$1.04M Buy
15,700
+12,400
+376% +$705K ﹤0.01% 2998
2025
Q2 		$182K Sell
3,300
-9,900
-75% -$475K ﹤0.01% 4611
2025
Q1 		$638K Buy
13,200
+12,400
+1,550% +$520K ﹤0.01% 3134
2024
Q4 		$30K Sell
800
-2,000
-71% -$87.2K ﹤0.01% 6365
2024
Q3 		$126K Sell
2,800
-800
-22% -$32.3K ﹤0.01% 4994
2024
Q2 		$124K Buy
3,600
+700
+24% +$20.5K ﹤0.01% 5144
2024
Q1 		$83K Sell
2,900
-1,500
-34% -$40.8K ﹤0.01% 5778
2023
Q4 		$100K Sell
4,400
-1,900
-30% -$33.2K ﹤0.01% 5387
2023
Q3 		$105K Sell
6,300
-1,300
-17% -$25.2K ﹤0.01% 5038
2023
Q2 		$209K Sell
7,600
-85,800
-92% -$2.15M ﹤0.01% 4249
2023
Q1 		$2.15M Buy
93,400
+65,200
+231% +$1.09M ﹤0.01% 1886
2022
Q4 		$307K Buy
28,200
+5,200
+23% +$43.9K ﹤0.01% 3711
2022
Q3 		$193K Sell
23,000
-14,100
-38% -$133K ﹤0.01% 4661
2022
Q2 		$293K Buy
37,100
+11,900
+47% +$144K ﹤0.01% 4132
2022
Q1 		$596K Buy
25,200
+5,500
+28% +$155K ﹤0.01% 3611
2021
Q4 		$673K Buy
19,700
+18,300
+1,307% +$578K ﹤0.01% 3415
2021
Q3 		$65K Hold
1,400
– – ﹤0.01% 7194
2021
Q2 		$62K Buy
1,400
+1,389
+12,627% +$45.8K ﹤0.01% 7385
2021
Q1 		$28K Buy
11
+10
+1,000% +$253 ﹤0.01% 7189
2020
Q4 		$2K Hold
1
– – ﹤0.01% 7999
2020
Q3 		$1K Buy
+1
New +$19 ﹤0.01% 7586

Other funds holding PTGX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
JJ
Johnson & Johnson New Brunswick, New Jersey $652M AUM 198.07% 1-Year Est. Return

Simplex Trading's PTGX Position: Q3 2025 in Review

Simplex Trading sold out of Protagonist Therapeutics (PTGX) in Q3 2025, closing a stake of 9,452 shares — an estimated $537K sold.

Simplex Trading first reported a position in PTGX in Q4 2020 and held it in 12 quarters. The position peaked at $1.45M in Q1 2023. 274 funds tracked by Wall St. Rank hold PTGX as of Q3 2025.

  • Simplex Trading reported no remaining Protagonist Therapeutics position as of Q3 2025 after selling out during the quarter.
  • Simplex Trading sold 9,452 Protagonist Therapeutics shares in Q3 2025, an estimated $537K.
  • Simplex Trading first reported a position in Protagonist Therapeutics in Q4 2020 and held it in 12 quarters.
  • Simplex Trading's Protagonist Therapeutics position peaked at $1.45M in Q1 2023.
  • 274 funds tracked by Wall St. Rank held Protagonist Therapeutics as of Q3 2025.

Based on Simplex Trading's 13F filing for Q3 2025, filed 12 Nov 2025.