Simplex Trading
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Simplex Trading’s Protagonist Therapeutics PTGX Stock Holding History

Simplex Trading’s Portfolio PTGX Stock Details PTGX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-9,452
Closed -$537K – 9848
2025
Q2 		$522K Sell
9,452
-16,482
-64% -$791K ﹤0.01% 3462
2025
Q1 		$1.25M Buy
25,934
+20,447
+373% +$857K ﹤0.01% 2479
2024
Q4 		$211K Buy
+5,487
New +$239K ﹤0.01% 4457
2024
Q2 		– Sell
-2,250
Closed -$65.9K – 9603
2024
Q1 		$65K Sell
2,250
-584
-21% -$15.9K ﹤0.01% 6031
2023
Q4 		$64K Buy
+2,834
New +$49.6K ﹤0.01% 5848
2023
Q3 		– Sell
-25,214
Closed -$489K – 9593
2023
Q2 		$696K Sell
25,214
-37,845
-60% -$947K ﹤0.01% 2966
2023
Q1 		$1.45M Buy
+63,059
New +$1.06M ﹤0.01% 2231
2022
Q4 		– Sell
-755
Closed -$6.37K – 10171
2022
Q3 		$6K Sell
755
-8,882
-92% -$84K ﹤0.01% 8668
2022
Q2 		$76K Buy
9,637
+4,665
+94% +$56.4K ﹤0.01% 5949
2022
Q1 		$117K Buy
4,972
+3,168
+176% +$89.3K ﹤0.01% 5929
2021
Q4 		$61K Buy
+1,804
New +$57K ﹤0.01% 6979
2021
Q1 		– Sell
-944
Closed -$23.9K – 9790
2020
Q4 		$19K Buy
+944
New +$20.3K ﹤0.01% 7009

Other funds holding PTGX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
FCM
Farallon Capital Management San Francisco, California $17.5B AUM 50.95% 1-Year Est. Return
UBS Group
UBS Group Zurich, Switzerland $666B AUM 30.12% 1-Year Est. Return
RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
JJ
Johnson & Johnson New Brunswick, New Jersey $652M AUM 198.07% 1-Year Est. Return

Simplex Trading's PTGX Position: Q3 2025 in Review

Simplex Trading sold out of Protagonist Therapeutics (PTGX) in Q3 2025, closing a stake of 9,452 shares — an estimated $537K sold.

Simplex Trading first reported a position in PTGX in Q4 2020 and held it in 12 quarters. The position peaked at $1.45M in Q1 2023. 275 funds tracked by Wall St. Rank hold PTGX as of Q3 2025.

  • Simplex Trading reported no remaining Protagonist Therapeutics position as of Q3 2025 after selling out during the quarter.
  • Simplex Trading sold 9,452 Protagonist Therapeutics shares in Q3 2025, an estimated $537K.
  • Simplex Trading first reported a position in Protagonist Therapeutics in Q4 2020 and held it in 12 quarters.
  • Simplex Trading's Protagonist Therapeutics position peaked at $1.45M in Q1 2023.
  • 275 funds tracked by Wall St. Rank held Protagonist Therapeutics as of Q3 2025.

Based on Simplex Trading's 13F filing for Q3 2025, filed 12 Nov 2025.