Simplex Trading
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Simplex Trading’s Milestone Pharmaceuticals MIST Stock Holding History

Simplex Trading’s Portfolio MIST Stock Details MIST Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$34K Buy
+28,600
New +$50.1K ﹤0.01% 6260
2025
Q4 		– Sell
-71,800
Closed -$143K – 9461
2025
Q3 		$143K Sell
71,800
-55,000
-43% -$96.7K ﹤0.01% 5337
2025
Q2 		$245K Buy
126,800
+79,000
+165% +$105K ﹤0.01% 4286
2025
Q1 		$38K Buy
+47,800
New +$95K ﹤0.01% 6051
2024
Q1 		– Sell
-1,500
Closed -$2K – 9442
2023
Q4 		$2K Hold
1,500
– – ﹤0.01% 8302
2023
Q3 		$4K Buy
+1,500
New +$4.66K ﹤0.01% 7784
2023
Q2 		– Sell
-1,200
Closed -$4K – 9551
2023
Q1 		$4K Sell
1,200
-12,900
-91% -$47.2K ﹤0.01% 8192
2022
Q4 		$55K Sell
14,100
-124,600
-90% -$656K ﹤0.01% 5757
2022
Q3 		$1.27M Buy
138,700
+137,800
+15,311% +$1.05M ﹤0.01% 2375
2022
Q2 		$5K Sell
900
-107,500
-99% -$661K ﹤0.01% 8841
2022
Q1 		$695K Buy
108,400
+107,600
+13,450% +$672K ﹤0.01% 3410
2021
Q4 		$5K Sell
800
-114,900
-99% -$688K ﹤0.01% 9534
2021
Q3 		$650K Hold
115,700
– – ﹤0.01% 3703
2021
Q2 		$636K Buy
115,700
+114,401
+8,807% +$649K ﹤0.01% 3789
2021
Q1 		$752K Buy
1,299
+1,267
+3,959% +$9.27K ﹤0.01% 2789
2020
Q4 		$21K Buy
+32
New +$214 ﹤0.01% 6943

Other funds holding MIST

RI
RTW Investments New York $10B AUM 135.35% 1-Year Est. Return
PBM
Propel Bio Management Los Angeles, California $159M AUM 60.94% 1-Year Est. Return
Two Sigma Investments
Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return
Goldman Sachs
Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return
Marshall Wace
Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return
SAM
Simplify Asset Management Las Vegas, Nevada $7.19B AUM 6.88% 1-Year Est. Return
Point72 Asset Management
Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return
Balyasny Asset Management
Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return
LPC
Lion Point Capital New York $16.7M AUM 119.35% 1-Year Est. Return

Simplex Trading's MIST Position: Q1 2026 in Review

Simplex Trading opened a new position in Milestone Pharmaceuticals (MIST) in Q1 2026: 149,291 shares worth $178K. The stake represents ﹤0.01% of the portfolio and ranks #4432 among its holdings. This is a return to the name: Simplex Trading previously reported a position in MIST as recently as Q3 2025.

Simplex Trading first reported a position in MIST in Q3 2020 and has held it in 10 quarters since. 85 funds tracked by Wall St. Rank hold MIST as of Q1 2026.

  • Simplex Trading held 149,291 shares of Milestone Pharmaceuticals worth $178K as of Q1 2026.
  • Milestone Pharmaceuticals was a new Simplex Trading position in Q1 2026.
  • Milestone Pharmaceuticals made up ﹤0.01% of Simplex Trading's portfolio in Q1 2026, its #4432 holding.
  • Simplex Trading first reported a position in Milestone Pharmaceuticals in Q3 2020 and has held it in 10 quarters since.
  • 85 funds tracked by Wall St. Rank held Milestone Pharmaceuticals as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.