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Milestone Pharmaceuticals
MIST

Overview Fund Activity

43 hedge funds and large institutions have $22.8M invested in Milestone Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 11 funds opening new positions, 9 increasing their positions, 9 reducing their positions, and 10 closing their positions.

Holders
43
Holders Change
–
Holders Change %
0%
% of All Funds
0.58%
Holding in Top 10
2
Holding in Top 10 Change
+2
Holding in Top 10 Change %
%
% of All Funds
0.03%
New
11
Increased
9
Reduced
9
Closed
10
Calls
$660K
Puts
$43K
Net Calls
+$617K
Net Calls Change
+$378K

Top Buyers

1
PBM
1
Propel Bio Management
California
$3.48M
2
UBS Group
2
UBS Group
Switzerland
$626K
3
SAM
3
Simplify Asset Management
Nevada
$1.92M
4
Goldman Sachs
4
Goldman Sachs
New York
$232K
5
VFA
5
Valeo Financial Advisors
Indiana
$254K

Top Sellers

1
Morgan Stanley
1
Morgan Stanley
New York
$1.59M
2
Millennium Management
2
Millennium Management
New York
$0
3
Group One Trading
3
Group One Trading
Illinois
$61.3K
4
SCM
4
Stonepine Capital Management
Oregon
$0
5
LPL Financial
5
LPL Financial
California
$21.4K
Name Market Value Shares Shares
Change 		Shares
Change %
RI
1
RTW Investments
New York
$4.86M 2,506,102 – –
PBM
2
Propel Bio Management
California
$3.48M 1,791,557 +340,000 +23%
AFA
3
Alta Fundamental Advisers
New York
$2.71M 1,398,977 -28,502 -2%
BCM
4
BML Capital Management
Indiana
$2.2M 1,136,091 – –
SAM
5
Simplify Asset Management
Nevada
$1.92M 990,000 +140,000 +16%
Morgan Stanley
6
Morgan Stanley
New York
$1.59M 820,421 -148,104 -15%
Toronto Dominion Bank
7
Toronto Dominion Bank
Ontario, Canada
$1.46M 750,000 – –
LPC
8
Lion Point Capital
New York
$1.06M 548,806 – –
BL
9
Bleichroeder LP
New York
$970K 500,000 – –
UBS Group
10
UBS Group
Switzerland
$626K 322,648 +211,125 +189%
XT
11
XTX Topco
Cayman Islands
$312K 160,963 +108,959 +210%
VFA
12
Valeo Financial Advisors
Indiana
$254K 130,699 +110,699 +553%
Goldman Sachs
13
Goldman Sachs
New York
$232K 119,449 +119,449 New
CCAM
14
Cascades Capital Asset Management
North Carolina
$130K 67,135 +67,135 New
Northern Trust
15
Northern Trust
Illinois
$103K 53,001 – –
Raymond James Financial
16
Raymond James Financial
Florida
$83.9K 43,235 +10,000 +30%
Focus Partners Wealth
17
Focus Partners Wealth
Massachusetts
$69.8K 36,000 +36,000 New
Royal Bank of Canada
18
Royal Bank of Canada
Ontario, Canada
$69K 35,600 +25,600 +256%
Jane Street
19
Jane Street
New York
$62K 31,933 +31,933 New
Group One Trading
20
Group One Trading
Illinois
$61.3K 31,616 -106,744 -77%
SIAG
21
Safeguard Investment Advisory Group
California
$48.6K 25,044 – –
Creative Planning
22
Creative Planning
Kansas
$45.4K 23,410 +10,000 +75%
SRL
23
Scientech Research LLC
New Jersey
$37K 19,064 -3,854 -17%
National Bank of Canada
24
National Bank of Canada
Quebec, Canada
$36.1K 18,700 – –
State Street
25
State Street
Massachusetts
$35.4K 18,246 -291 -2%
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