Milestone Pharmaceuticals
MIST
61 hedge funds and large institutions have $68.3M invested in Milestone Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 26 funds opening new positions, 18 increasing their positions, 4 reducing their positions, and 7 closing their positions.
350% more repeat investments, than reductions
Existing positions increased: 18 | Existing positions reduced: 4
271% more first-time investments, than exits
New positions opened: 26 | Existing positions closed: 7
198% more capital invested
Capital invested by funds: $22.9M → $68.3M (+$45.4M)
42% more funds holding
Funds holding: 43 → 61 (+18)
18.06% more ownership
Funds ownership: 22.1% → 40.17% (+18%)
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
34% less call options, than puts
Call options by funds: $423K | Put options by funds: $641K
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Adage Capital Partners
Boston,
Massachusetts
|
+$12.3M |
| 2 |
PBM
Propel Bio Management
Los Angeles,
California
|
+$5.86M |
| 3 |
O
OrbiMed
New York
|
+$5.67M |
| 4 |
Morgan Stanley
New York
|
+$3.78M |
| 5 |
SAM
Simplify Asset Management
Las Vegas,
Nevada
|
+$3.24M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
AFA
Alta Fundamental Advisers
New York
|
-$2.71M |
| 2 |
BCM
BML Capital Management
Zionsville,
Indiana
|
-$2.2M |
| 3 |
BL
Bleichroeder LP
New York
|
-$970K |
| 4 |
Group One Trading
Chicago,
Illinois
|
-$43.2K |
| 5 |
SRL
Scientech Research LLC
Jersey City,
New Jersey
|
-$37K |
MIST Hedge Fund Activity: Q3 2025 in Review
61 of the 7,645 institutional investors tracked by Wall St. Rank reported a position in Milestone Pharmaceuticals (MIST) for Q3 2025, worth a combined $68.3M — up 198% from $22.9M a quarter earlier.
Buyers outnumbered sellers: 26 funds opened new MIST positions and 7 closed out — a net gain of 19 holders — while 18 added to existing stakes and 4 trimmed.
The largest buyer was Adage Capital Partners, opening a new position worth an estimated $12.3M. The largest seller was Alta Fundamental Advisers, exiting entirely with an estimated $2.71M sold.
- 61 institutional investors held Milestone Pharmaceuticals (MIST) as of Q3 2025, up from 43 in Q2 2025.
- Funds reported $68.3M of Milestone Pharmaceuticals stock for Q3 2025, up 198% quarter-over-quarter.
- 26 funds opened new Milestone Pharmaceuticals positions in Q3 2025 and 7 closed out, a net change of +19 holders.
- The largest Milestone Pharmaceuticals buyer in Q3 2025 was Adage Capital Partners, an estimated $12.3M added.
- The largest Milestone Pharmaceuticals seller in Q3 2025 was Alta Fundamental Advisers, an estimated $2.71M sold.
Based on aggregated 13F filings for Q3 2025.