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Milestone Pharmaceuticals
MIST

28 hedge funds and large institutions have $133M invested in Milestone Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 4 funds opening new positions, 9 increasing their positions, 4 reducing their positions, and 3 closing their positions.

New
Increased
Maintained
Reduced
Closed

125% more repeat investments, than reductions

Existing positions increased: 9 | Existing positions reduced: 4

33% more first-time investments, than exits

New positions opened: 4 | Existing positions closed: 3

16% more capital invested

Capital invested by funds: $114M → $133M (+$18.6M)

4% more funds holding

Funds holding: 27 → 28 (+1)

0.92% more ownership

Funds ownership: 66.85% → 67.77% (+0.92%)

0% more funds holding in top 10

Funds holding in top 10: 1 → 1 (0)

Holders
28
Holders Change
+1
Holders Change %
+3.7%
% of All Funds
0.43%
Holding in Top 10
1
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.02%
New
4
Increased
9
Reduced
4
Closed
3
Calls
$6K
Puts
–
Net Calls
+$6K
Net Calls Change
-$2.56M

Top Buyers

1
Millennium Management
Millennium Management
New York
+$1.74M
2
BL
Bleichroeder LP
New York
+$1.5M
3
PVI
Pura Vida Investments
New York
+$486K
4
EP
Eversept Partners
New York
+$201K
5
Dimensional Fund Advisors
Dimensional Fund Advisors
Texas
+$42.3K

Top Sellers

1
BC
Boxer Capital
California
-$2M
2
Morgan Stanley
Morgan Stanley
New York
-$165K
3
Renaissance Technologies
Renaissance Technologies
New York
-$151K
4
Citadel Advisors
Citadel Advisors
Florida
-$60K
5
SFI
Susquehanna Fundamental Investments
Pennsylvania
-$47.7K
Name Holding Trade Value Shares
Change 		Change in
Stake
RI
1
RTW Investments
New York
$28.3M – – –
O
2
OrbiMed
New York
$16.9M – – –
NHAS
3
Novo Holdings A/S
Denmark
$16.6M – – –
RCM
4
RA Capital Management
Massachusetts
$14.7M – – –
BC
5
Boxer Capital
California
$14.7M -$2M -333,333 -13%
IC
6
Ikarian Capital
Texas
$11.5M – – –
Millennium Management
7
Millennium Management
New York
$6.46M +$1.74M +290,626 +42%
PVI
8
Pura Vida Investments
New York
$6.1M +$486K +81,199 +10%
SCM
9
Suvretta Capital Management
New York
$5.58M – – –
Morgan Stanley
10
Morgan Stanley
New York
$5.41M -$165K -27,566 -3%
BL
11
Bleichroeder LP
New York
$1.64M +$1.5M +250,000 New
Barclays
12
Barclays
United Kingdom
$1.33M +$13.9K +2,325 +1%
BFM
13
Boothbay Fund Management
New York
$1.14M – – –
EP
14
Eversept Partners
New York
$964K +$201K +33,568 +30%
Dimensional Fund Advisors
15
Dimensional Fund Advisors
Texas
$345K +$42.3K +7,061 +16%
SFI
16
Susquehanna Fundamental Investments
Pennsylvania
$209K -$47.7K -7,960 -20%
Royal Bank of Canada
17
Royal Bank of Canada
Ontario, Canada
$170K -$1.15K -192 -0.7%
State Street
18
State Street
Massachusetts
$136K +$2.3K +384 +2%
Geode Capital Management
19
Geode Capital Management
Massachusetts
$115K – – –
National Bank of Canada
20
National Bank of Canada
Quebec, Canada
$96K +$88.3K +14,742 New
Goldman Sachs
21
Goldman Sachs
New York
$79K – – –
Acadian Asset Management
22
Acadian Asset Management
Massachusetts
$79K +$28.7K +4,785 +63%
FDCDDQ
23
Federation des caisses Desjardins du Quebec
Quebec, Canada
$68.8K – – –
JP Morgan Chase
24
JP Morgan Chase
New York
$46K +$41.8K +6,974 New
Osaic Holdings
25
Osaic Holdings
Arizona
$17K +$4.25K +709 +39%
1
2

MIST Hedge Fund Activity: Q4 2021 in Review

28 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Milestone Pharmaceuticals (MIST) for Q4 2021, worth a combined $133M — up 16% from $114M a quarter earlier.

Buyers outnumbered sellers: 4 funds opened new MIST positions and 3 closed out — a net gain of 1 holder — while 9 added to existing stakes and 4 trimmed.

The largest buyer was Millennium Management, adding an estimated $1.74M. The largest seller was Boxer Capital, cutting an estimated $2M.

  • 28 institutional investors held Milestone Pharmaceuticals (MIST) as of Q4 2021, up from 27 in Q3 2021.
  • Funds reported $133M of Milestone Pharmaceuticals stock for Q4 2021, up 16% quarter-over-quarter.
  • 4 funds opened new Milestone Pharmaceuticals positions in Q4 2021 and 3 closed out, a net change of +1 holder.
  • The largest Milestone Pharmaceuticals buyer in Q4 2021 was Millennium Management, an estimated $1.74M added.
  • The largest Milestone Pharmaceuticals seller in Q4 2021 was Boxer Capital, an estimated $2M sold.

Based on aggregated 13F filings for Q4 2021.