Simplex Trading’s Structure Therapeutics GPCR Stock Holding History

Simplex Trading’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q3	$288K	Buy	9,200 +900	+11%	+$42.2K	﹤0.01%	4216
2026 Q2	$445K	Sell	8,300 -700	-8%	-$31K	﹤0.01%	3747
2026 Q1	$434K	Buy	9,000 +1,400	+18%	+$95.8K	﹤0.01%	3443
2025 Q4	$529K	Sell	7,600 -14,600	-66%	-$596K	﹤0.01%	3254
2025 Q3	$621K	Sell	22,200 -14,400	-39%	-$287K	﹤0.01%	3558
2025 Q2	$759K	Sell	36,600 -3,700	-9%	-$81.4K	﹤0.01%	3072
2025 Q1	$697K	Buy	40,300 +11,000	+38%	+$269K	﹤0.01%	3040
2024 Q4	$794K	Buy	29,300 +7,400	+34%	+$263K	﹤0.01%	3076
2024 Q3	$961K	Sell	21,900 -26,600	-55%	-$1.03M	﹤0.01%	2952
2024 Q2	$1.9M	Buy	48,500 +21,300	+78%	+$875K	﹤0.01%	2245
2024 Q1	$1.16M	Sell	27,200 -7,300	-21%	-$308K	﹤0.01%	2955
2023 Q4	$1.41M	Buy	+34,500	New	+$1.98M	﹤0.01%	2674

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $2.32T AUM 44.66% 1-Year Est. Return

Principal Financial Group Des Moines, Iowa $195B AUM 21.17% 1-Year Est. Return

Siren LLC Greenwich, Connecticut $4.23B AUM 121.47% 1-Year Est. Return

Aberdeen Group Edinburgh, United Kingdom $72.4B AUM 31.32% 1-Year Est. Return

Capitolis Liquid Global Markets New York $22.4B AUM 40.52% 1-Year Est. Return

Pacific Heights Asset Management San Francisco, California $3.1B AUM 37.54% 1-Year Est. Return

JP Morgan Chase New York $1.84T AUM 33.86% 1-Year Est. Return

UBS Group Zurich, Switzerland $765B AUM 28.39% 1-Year Est. Return

NEXTBio Capital Management Menlo Park, California $234M AUM 176.49% 1-Year Est. Return

American Century Companies Kansas City, Missouri $229B AUM 33.35% 1-Year Est. Return

Simplex Trading's GPCR Position: Q3 2026 in Review

Simplex Trading reduced its Structure Therapeutics (GPCR) stake by 68% in Q3 2026, selling an estimated $250K and leaving 2,535 shares worth $79.3K. The position accounts for ﹤0.01% of the portfolio, ranked #5696.

Simplex Trading first reported a position in GPCR in Q4 2023 and has held it in 11 quarters since. The position peaked at $6.45M in Q4 2025. 98 funds tracked by Wall St. Rank hold GPCR as of Q3 2026.

Simplex Trading held 2,535 shares of Structure Therapeutics worth $79.3K as of Q3 2026.
Simplex Trading sold 5,336 Structure Therapeutics shares in Q3 2026, an estimated $250K.
Structure Therapeutics made up ﹤0.01% of Simplex Trading's portfolio in Q3 2026, its #5696 holding.
Simplex Trading first reported a position in Structure Therapeutics in Q4 2023 and has held it in 11 quarters since.
Simplex Trading's Structure Therapeutics position peaked at $6.45M in Q4 2025.
98 funds tracked by Wall St. Rank held Structure Therapeutics as of Q3 2026.

Based on Simplex Trading's 13F filing for Q3 2026, filed 4 Nov 2026.