Simplex Trading
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Simplex Trading’s Structure Therapeutics GPCR Stock Holding History

Simplex Trading’s Portfolio GPCR Stock Details GPCR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$445K Sell
8,300
-700
-8% -$31K ﹤0.01% 3747
2026
Q1 		$434K Buy
9,000
+1,400
+18% +$95.8K ﹤0.01% 3443
2025
Q4 		$529K Sell
7,600
-14,600
-66% -$596K ﹤0.01% 3254
2025
Q3 		$621K Sell
22,200
-14,400
-39% -$287K ﹤0.01% 3558
2025
Q2 		$759K Sell
36,600
-3,700
-9% -$81.4K ﹤0.01% 3072
2025
Q1 		$697K Buy
40,300
+11,000
+38% +$269K ﹤0.01% 3040
2024
Q4 		$794K Buy
29,300
+7,400
+34% +$263K ﹤0.01% 3076
2024
Q3 		$961K Sell
21,900
-26,600
-55% -$1.03M ﹤0.01% 2952
2024
Q2 		$1.9M Buy
48,500
+21,300
+78% +$875K ﹤0.01% 2245
2024
Q1 		$1.17M Sell
27,200
-7,300
-21% -$308K ﹤0.01% 2955
2023
Q4 		$1.41M Buy
+34,500
New +$1.98M ﹤0.01% 2674

Other funds holding GPCR

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
DTC
Deep Track Capital Greenwich, Connecticut $6.87B AUM 205.24% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return

Simplex Trading's GPCR Position: Q2 2026 in Review

Simplex Trading opened a new position in Structure Therapeutics (GPCR) in Q2 2026: 7,871 shares worth $422K. The stake represents ﹤0.01% of the portfolio and ranks #3820 among its holdings. This is a return to the name: Simplex Trading previously reported a position in GPCR as recently as Q4 2025.

Simplex Trading first reported a position in GPCR in Q4 2023 and has held it in 10 quarters since. The position peaked at $6.45M in Q4 2025. 191 funds tracked by Wall St. Rank hold GPCR as of Q2 2026.

  • Simplex Trading held 7,871 shares of Structure Therapeutics worth $422K as of Q2 2026.
  • Structure Therapeutics was a new Simplex Trading position in Q2 2026.
  • Structure Therapeutics made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #3820 holding.
  • Simplex Trading first reported a position in Structure Therapeutics in Q4 2023 and has held it in 10 quarters since.
  • Simplex Trading's Structure Therapeutics position peaked at $6.45M in Q4 2025.
  • 191 funds tracked by Wall St. Rank held Structure Therapeutics as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.