Simplex Trading’s Structure Therapeutics GPCR Stock Holding History

Simplex Trading’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$434K	Buy	9,000 +1,400	+18%	+$95.8K	﹤0.01%	3443
2025 Q4	$529K	Sell	7,600 -14,600	-66%	-$596K	﹤0.01%	3254
2025 Q3	$621K	Sell	22,200 -14,400	-39%	-$287K	﹤0.01%	3558
2025 Q2	$759K	Sell	36,600 -3,700	-9%	-$81.4K	﹤0.01%	3072
2025 Q1	$697K	Buy	40,300 +11,000	+38%	+$269K	﹤0.01%	3040
2024 Q4	$794K	Buy	29,300 +7,400	+34%	+$263K	﹤0.01%	3076
2024 Q3	$961K	Sell	21,900 -26,600	-55%	-$1.03M	﹤0.01%	2952
2024 Q2	$1.9M	Buy	48,500 +21,300	+78%	+$875K	﹤0.01%	2245
2024 Q1	$1.17M	Sell	27,200 -7,300	-21%	-$308K	﹤0.01%	2955
2023 Q4	$1.41M	Buy	+34,500	New	+$1.98M	﹤0.01%	2674

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

DTC

Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return

BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Simplex Trading's GPCR Position: Q1 2026 in Review

Simplex Trading sold out of Structure Therapeutics (GPCR) in Q1 2026, closing a stake of 92,668 shares — an estimated $6.34M sold.

Simplex Trading first reported a position in GPCR in Q4 2023 and held it in 9 quarters. The position peaked at $6.45M in Q4 2025. 196 funds tracked by Wall St. Rank hold GPCR as of Q1 2026.

Simplex Trading reported no remaining Structure Therapeutics position as of Q1 2026 after selling out during the quarter.
Simplex Trading sold 92,668 Structure Therapeutics shares in Q1 2026, an estimated $6.34M.
Simplex Trading first reported a position in Structure Therapeutics in Q4 2023 and held it in 9 quarters.
Simplex Trading's Structure Therapeutics position peaked at $6.45M in Q4 2025.
196 funds tracked by Wall St. Rank held Structure Therapeutics as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.