Simplex Trading’s Structure Therapeutics GPCR Stock Holding History

Simplex Trading’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$930K	Buy	19,300 +6,500	+51%	+$445K	﹤0.01%	2577
2025 Q4	$890K	Sell	12,800 -700	-5%	-$28.6K	﹤0.01%	2748
2025 Q3	$378K	Buy	13,500 +7,200	+114%	+$143K	﹤0.01%	4172
2025 Q2	$130K	Sell	6,300 -9,500	-60%	-$209K	﹤0.01%	4970
2025 Q1	$273K	Sell	15,800 -9,000	-36%	-$220K	﹤0.01%	4005
2024 Q4	$672K	Buy	24,800 +16,800	+210%	+$596K	﹤0.01%	3246
2024 Q3	$351K	Sell	8,000 -58,700	-88%	-$2.27M	﹤0.01%	3969
2024 Q2	$2.62M	Buy	66,700 +1,700	+3%	+$69.8K	﹤0.01%	1964
2024 Q1	$2.79M	Buy	65,000 +54,100	+496%	+$2.28M	﹤0.01%	2091
2023 Q4	$444K	Buy	+10,900	New	+$625K	﹤0.01%	3822

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

DTC

Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return

BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

Principal Financial Group Des Moines, Iowa $187B AUM 18.48% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

Simplex Trading's GPCR Position: Q1 2026 in Review

Simplex Trading sold out of Structure Therapeutics (GPCR) in Q1 2026, closing a stake of 92,668 shares — an estimated $6.34M sold.

Simplex Trading first reported a position in GPCR in Q4 2023 and held it in 9 quarters. The position peaked at $6.45M in Q4 2025. 196 funds tracked by Wall St. Rank hold GPCR as of Q1 2026.

Simplex Trading reported no remaining Structure Therapeutics position as of Q1 2026 after selling out during the quarter.
Simplex Trading sold 92,668 Structure Therapeutics shares in Q1 2026, an estimated $6.34M.
Simplex Trading first reported a position in Structure Therapeutics in Q4 2023 and held it in 9 quarters.
Simplex Trading's Structure Therapeutics position peaked at $6.45M in Q4 2025.
196 funds tracked by Wall St. Rank held Structure Therapeutics as of Q1 2026.

Based on Simplex Trading's 13F filing for Q1 2026, filed 14 May 2026.