Simplex Trading’s Structure Therapeutics GPCR Stock Holding History

Simplex Trading’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$338K	Sell	6,300 -13,000	-67%	-$575K	﹤0.01%	4088
2026 Q1	$930K	Buy	19,300 +6,500	+51%	+$445K	﹤0.01%	2577
2025 Q4	$890K	Sell	12,800 -700	-5%	-$28.6K	﹤0.01%	2748
2025 Q3	$378K	Buy	13,500 +7,200	+114%	+$143K	﹤0.01%	4172
2025 Q2	$130K	Sell	6,300 -9,500	-60%	-$209K	﹤0.01%	4970
2025 Q1	$273K	Sell	15,800 -9,000	-36%	-$220K	﹤0.01%	4005
2024 Q4	$672K	Buy	24,800 +16,800	+210%	+$596K	﹤0.01%	3246
2024 Q3	$351K	Sell	8,000 -58,700	-88%	-$2.27M	﹤0.01%	3969
2024 Q2	$2.62M	Buy	66,700 +1,700	+3%	+$69.8K	﹤0.01%	1964
2024 Q1	$2.79M	Buy	65,000 +54,100	+496%	+$2.28M	﹤0.01%	2091
2023 Q4	$444K	Buy	+10,900	New	+$625K	﹤0.01%	3822

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return

Jupiter Topco New York $245B AUM

DTC

Deep Track Capital Greenwich, Connecticut $6.87B AUM 205.24% 1-Year Est. Return

BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return

Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return

OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return

Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return

American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return

Simplex Trading's GPCR Position: Q2 2026 in Review

Simplex Trading opened a new position in Structure Therapeutics (GPCR) in Q2 2026: 7,871 shares worth $422K. The stake represents ﹤0.01% of the portfolio and ranks #3820 among its holdings. This is a return to the name: Simplex Trading previously reported a position in GPCR as recently as Q4 2025.

Simplex Trading first reported a position in GPCR in Q4 2023 and has held it in 10 quarters since. The position peaked at $6.45M in Q4 2025. 191 funds tracked by Wall St. Rank hold GPCR as of Q2 2026.

Simplex Trading held 7,871 shares of Structure Therapeutics worth $422K as of Q2 2026.
Structure Therapeutics was a new Simplex Trading position in Q2 2026.
Structure Therapeutics made up ﹤0.01% of Simplex Trading's portfolio in Q2 2026, its #3820 holding.
Simplex Trading first reported a position in Structure Therapeutics in Q4 2023 and has held it in 10 quarters since.
Simplex Trading's Structure Therapeutics position peaked at $6.45M in Q4 2025.
191 funds tracked by Wall St. Rank held Structure Therapeutics as of Q2 2026.

Based on Simplex Trading's 13F filing for Q2 2026, filed 12 Aug 2026.