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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+4.46%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$6.63B
AUM Growth
+$3.92M
Cap. Flow
+$439M
Cap. Flow %
6.62%
Top 10 Hldgs %
41.1%
Holding
130
New
17
Increased
26
Reduced
9
Closed
10

Top Buys

Rank Stock Value
1
TMO icon
Thermo Fisher Scientific
TMO
+$228M
2
PEN icon
Penumbra
PEN
+$104M
3
TNYA icon
Tenaya Therapeutics
TNYA
+$52.8M
4
SGHT icon
Sight Sciences
SGHT
+$42.2M
5
MGNX icon
MacroGenics
MGNX
+$34.4M

Top Sells

Rank Stock Value
1
QDEL icon
QuidelOrtho
QDEL
+$113M
2
PTGX icon
Protagonist Therapeutics
PTGX
+$74.8M
3
SPY icon
State Street SPDR S&P 500 ETF Trust
SPY
+$54.3M
4
MDXG icon
MiMedx Group
MDXG
+$27.1M
5
TRIL
Trillium Therapeutics Inc.
TRIL
+$20.3M

Sector Composition

Rank Sector Weight
1 Healthcare 91.48%
2 Financials 0.49%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
PNT
101
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$3.77M 0.06%
490,000
– –
MXCT icon
102
MaxCyte
MXCT
$126M
$3.36M 0.05%
+275,000
New +$4.15M
MAAC
103
DELISTED
Montes Archimedes Acquisition Corp. Class A Common Stock
MAAC
$3.16M 0.05%
+400,000
New +$3.97M
WGS icon
104
GeneDx Holdings
WGS
$2.3B
$2.94M 0.04%
+12,121
New +$4.16M
MSAC
105
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$2.92M 0.04%
300,000
– –
CVRX icon
106
CVRx
CVRX
$63.4M
$2.48M 0.04%
150,000
– –
TBIO
107
DELISTED
Telesis Bio, Inc. Common Stock
TBIO
$2.23M 0.03%
11,111
– –
TWST icon
108
Twist Bioscience
TWST
$7.25B
$1.98M 0.03%
18,473
– –
MIRO
109
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
$1.95M 0.03%
280,000
– –
RXST icon
110
RxSight
RXST
$260M
$1.9M 0.03%
+150,000
New +$2.06M
MDXG icon
111
MiMedx Group
MDXG
$633M
$1.79M 0.03%
295,748
-2,404,572
-89% -$27.1M
PROF
112
Profound Medical
PROF
$269M
$1.79M 0.03%
122,098
– –
BOLT icon
113
Bolt Biotherapeutics
BOLT
$7.78M
$1.6M 0.02%
6,318
– –
AKYA
114
DELISTED
Akoya BioSciences
AKYA
$1.4M 0.02%
100,000
– –
MASS icon
115
908 Devices
MASS
$364M
$1.3M 0.02%
40,000
– –
OMIC
116
DELISTED
Singular Genomics Systems, Inc. Common Stock
OMIC
$1.12M 0.02%
3,333
– –
ZY
117
DELISTED
Zymergen Inc. Common Stock
ZY
$922K 0.01%
70,000
– –
BNR
118
Burning Rock Biotech
BNR
$92.9M
$536K 0.01%
3,000
– –
RCOR.WS
119
DELISTED
Renovacor, Inc. Warrants, entitling the holder thereof to purchase one-half (1/2) of a share of common stock at a price of $11. 50 per whole share
RCOR.WS
$224K ﹤0.01%
+350,000
New +$273K
MSACW
120
DELISTED
Medicus Sciences Acquisition Corp. Warrant
MSACW
$24K ﹤0.01%
33,331
– –
BDSX icon
121
Biodesix
BDSX
$248M
– –
-6,250
Closed -$1.65M
ELUT icon
122
Elutia
ELUT
$37.6M
– –
-125,000
Closed -$1.2M
MRVI icon
123
Maravai LifeSciences
MRVI
$919M
– –
-70,000
Closed -$2.92M
PSNL icon
124
Personalis
PSNL
$1.51B
– –
-127,501
Closed -$3.23M
QDEL icon
125
QuidelOrtho
QDEL
$838M
– –
-878,533
Closed -$113M
2 3 4
5
6

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RTW Investments's Q3 2021 Portfolio in Review

As of Q3 2021, RTW Investments held 130 positions worth $6.63B, up 0.06% from $6.63B the previous quarter. Its ten largest holdings account for 41% of the portfolio.

RTW Investments deployed $439M of net new capital in Q3 2021, opening 17 new positions and adding to 26 existing holdings. Its largest new stake was Thermo Fisher Scientific: 416,000 shares worth $238M.

By sector, the portfolio is most concentrated in Healthcare at 91% of assets, up from 88% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was Protagonist Therapeutics, an estimated $74.8M trimmed.

  • RTW Investments's largest Q3 2021 buy was Thermo Fisher Scientific: 416,000 shares worth $238M.
  • RTW Investments added most to MacroGenics in Q3 2021, an estimated $34.4M increase.
  • RTW Investments's biggest Q3 2021 reduction was Protagonist Therapeutics, cutting an estimated $74.8M.
  • RTW Investments fully exited QuidelOrtho in Q3 2021, selling an estimated $113M.
  • RTW Investments's ten largest holdings make up 41% of its $6.63B portfolio in Q3 2021.
  • RTW Investments opened 17 new positions and closed 10 in Q3 2021.
  • RTW Investments's portfolio value rose 0.06% quarter-over-quarter to $6.63B.

Based on RTW Investments's 13F filing for Q3 2021, filed 15 Nov 2021.