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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+9.72%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$6.63B
AUM Growth
+$221M
Cap. Flow
-$85.5M
Cap. Flow %
-1.29%
Top 10 Hldgs %
45.03%
Holding
125
New
14
Increased
22
Reduced
8
Closed
12

Top Buys

Rank Stock Value
1
EPIX
ESSA Pharma
EPIX
+$80.5M
2
MASI
Masimo
MASI
+$52.8M
3
RGNX icon
Regenxbio
RGNX
+$48M
4
GHRS icon
GH Research
GHRS
+$44.3M
5
GH icon
Guardant Health
GH
+$41.5M

Top Sells

Rank Stock Value
1
CERN
Cerner Corp
CERN
+$128M
2
ARVN icon
Arvinas
ARVN
+$107M
3
IMVT icon
Immunovant
IMVT
+$102M
4
TBIO
Translate Bio, Inc. Common Stock
TBIO
+$72.3M
5
CRIS icon
Curis
CRIS
+$41M

Sector Composition

Rank Sector Weight
1 Healthcare 88.48%
2 Financials 0.38%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
ARGX icon
76
argenx
ARGX
$55.2B
$9.56M 0.14%
31,752
– –
CTMX icon
77
CytomX Therapeutics
CTMX
$731M
$8.87M 0.13%
1,400,939
-132,819
-9% -$1.03M
CNTB
78
Connect Biopharma Holdings
CNTB
$138M
$8.79M 0.13%
450,000
– –
RCOR
79
DELISTED
Renovacor, Inc.
RCOR
$8.3M 0.13%
837,540
– –
MLTX icon
80
MoonLake Immunotherapeutics
MLTX
$1.55B
$7.76M 0.12%
750,000
– –
AFIB
81
DELISTED
Acutus Medical Inc
AFIB
$7.67M 0.12%
451,834
– –
TNGX icon
82
Tango Therapeutics
TNGX
$4.43B
$6.83M 0.1%
600,000
– –
RACB
83
DELISTED
Research Alliance Corp. II Class A Common Stock
RACB
$6.46M 0.1%
637,000
– –
BLSA
84
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$6.45M 0.1%
612,500
– –
ITMR
85
DELISTED
Itamar Medical Ltd. American Depository Shares
ITMR
$6.33M 0.1%
268,609
– –
APVO icon
86
Aptevo Therapeutics
APVO
$5.15M
– –
0
– –
RCEL icon
87
Avita Medical
RCEL
$229M
$5.75M 0.09%
280,000
– –
ARYD
88
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
$5.36M 0.08%
500,000
– –
PNT
89
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$5.03M 0.08%
490,000
– –
SMIHU
90
DELISTED
Summit Healthcare Acquisition Corp. Units
SMIHU
$5M 0.08%
+500,000
New +$5M
SRRK icon
91
Scholar Rock
SRRK
$6.2B
$4.67M 0.07%
161,612
– –
TBIO
92
DELISTED
Telesis Bio, Inc. Common Stock
TBIO
$4.4M 0.07%
+11,111
New +$3.93M
CVRX icon
93
CVRx
CVRX
$66.6M
$4.2M 0.06%
+150,000
New +$4.2M
IMTX icon
94
Immatics
IMTX
$1.3B
$4.06M 0.06%
350,000
– –
FVAM
95
DELISTED
5:01 Acquisition Corp
FVAM
$3.91M 0.06%
392,000
– –
CHAQ.U
96
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
$3.64M 0.06%
350,000
– –
MIRO
97
DELISTED
Miromatrix Medical Inc. Common Stock
MIRO
$3.26M 0.05%
+280,000
New +$3.6M
PSNL icon
98
Personalis
PSNL
$1.47B
$3.23M 0.05%
127,501
– –
MRVI icon
99
Maravai LifeSciences
MRVI
$872M
$2.92M 0.04%
70,000
– –
MSAC
100
DELISTED
Medicus Sciences Acquisition Corp. Class A Ordinary Share
MSAC
$2.9M 0.04%
+300,000
New +$2.93M
1 2 3
4
5

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RTW Investments's Q2 2021 Portfolio in Review

As of Q2 2021, RTW Investments held 125 positions worth $6.63B, up 3.5% from $6.41B the previous quarter. Its ten largest holdings account for 45% of the portfolio.

RTW Investments's Q2 2021 filing shows 14 new, 22 increased, 8 reduced and 12 closed positions. Its largest new stake was GH Research: 2,168,957 shares worth $42.7M. The largest sale was Cerner Corp, an estimated $128M.

By sector, the portfolio is most concentrated in Healthcare at 88% of assets, up from 88% a quarter earlier, followed by Financials.

  • RTW Investments's largest Q2 2021 buy was GH Research: 2,168,957 shares worth $42.7M.
  • RTW Investments added most to ESSA Pharma in Q2 2021, an estimated $80.5M increase.
  • RTW Investments's biggest Q2 2021 reduction was Rocket Pharmaceuticals, cutting an estimated $31.5M.
  • RTW Investments fully exited Cerner Corp in Q2 2021, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 45% of its $6.63B portfolio in Q2 2021.
  • RTW Investments opened 14 new positions and closed 12 in Q2 2021.
  • RTW Investments's portfolio value rose 3.5% quarter-over-quarter to $6.63B.

Based on RTW Investments's 13F filing for Q2 2021, filed 13 Aug 2021.