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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+60.02%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$5.96B
AUM Growth
+$1.81B
Cap. Flow
+$286M
Cap. Flow %
4.79%
Top 10 Hldgs %
47.57%
Holding
116
New
25
Increased
35
Reduced
12
Closed
14

Top Buys

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$94.3M
2
TARS icon
Tarsus Pharmaceuticals
TARS
+$70.2M
3
CCCC icon
C4 Therapeutics
CCCC
+$62.3M
4
ARVN icon
Arvinas
ARVN
+$61.8M
5
ILMN icon
Illumina
ILMN
+$61.2M

Sector Composition

Rank Sector Weight
1 Healthcare 94%
2 Financials 0.18%
3 Materials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
SNCE
76
DELISTED
Science 37 Holdings, Inc. Common Stock
SNCE
$6.94M 0.12%
+32,500
New +$6.76M
TNGX icon
77
Tango Therapeutics
TNGX
$4.41B
$6.86M 0.12%
600,000
BLSA
78
DELISTED
BCLS Acquisition Corp. Class A Ordinary Shares
BLSA
$6.82M 0.11%
+612,500
New +$6.57M
PNT
79
DELISTED
POINT Biopharma Global Inc. Common Stock
PNT
$6.82M 0.11%
490,000
INMD icon
80
InMode
INMD
$880M
$5.93M 0.1%
249,998
-250,002
-50% -$5.28M
NAUT icon
81
Nautilus Biotechnolgy
NAUT
$115M
$5.42M 0.09%
500,000
PSNL icon
82
Personalis
PSNL
$1.51B
$4.67M 0.08%
127,501
-127,499
-50% -$3.85M
ITMR
83
DELISTED
Itamar Medical Ltd. American Depository Shares
ITMR
$4.54M 0.08%
228,609
-228,609
-50% -$4.57M
FVAM
84
DELISTED
5:01 Acquisition Corp
FVAM
$3.99M 0.07%
+392,000
New +$3.96M
PHGE icon
85
BiomX
PHGE
$1.85M
$3.83M 0.06%
3,158
PANA.U
86
DELISTED
Panacea Acquisition Corp. Units, each consisting of one share of Class A common stock and one-third
PANA.U
$3.83M 0.06%
300,000
IMTX icon
87
Immatics
IMTX
$1.32B
$3.78M 0.06%
350,000
CHAQ.U
88
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
$3.71M 0.06%
350,000
TWST icon
89
Twist Bioscience
TWST
$7.25B
$2.61M 0.04%
18,473
BDSX icon
90
Biodesix
BDSX
$248M
$2.52M 0.04%
+6,250
New +$1.95M
PROF
91
Profound Medical
PROF
$269M
$2.51M 0.04%
122,098
-122,095
-50% -$2.25M
MASS icon
92
908 Devices
MASS
$364M
$2.28M 0.04%
+40,000
New +$2.34M
MRVI icon
93
Maravai LifeSciences
MRVI
$919M
$1.96M 0.03%
+70,000
New +$1.95M
OSUR icon
94
OraSure Technologies
OSUR
$279M
$1.95M 0.03%
184,000
-1,891,082
-91% -$24.8M
ELUT icon
95
Elutia
ELUT
$37.6M
$1.7M 0.03%
+125,000
New +$1.56M
VINCW
96
DELISTED
Vincerx Pharma, Inc. Warrant
VINCW
$1.65M 0.03%
+500,000
New +$1.66M
CEREW
97
DELISTED
Cerevel Therapeutics Holdings, Inc. Warrant
CEREW
$942K 0.02%
+166,666
New +$672K
BNR
98
Burning Rock Biotech
BNR
$92.9M
$693K 0.01%
3,000
BIOR
99
DELISTED
Biora Therapeutics, Inc. Common Stock
BIOR
$531K 0.01%
400
-700
-64% -$1.03M
PHGE.WS
100
DELISTED
BiomX Inc. Warrants to purchase one-half of a share of Common Stock
PHGE.WS
$480K 0.01%
600,000

Similar funds

RTW Investments's Q4 2020 Portfolio in Review

As of Q4 2020, RTW Investments held 116 positions worth $5.96B, up 44% from $4.15B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $286M of net new capital in Q4 2020, opening 25 new positions and adding to 35 existing holdings. Its largest new stake was Globus Medical: 1,640,859 shares worth $107M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 93% a quarter earlier, followed by Financials and Materials.

On the sell side, the largest reduction was OraSure Technologies, an estimated $24.8M trimmed.

  • RTW Investments's largest Q4 2020 buy was Globus Medical: 1,640,859 shares worth $107M.
  • RTW Investments added most to Illumina in Q4 2020, an estimated $61.2M increase.
  • RTW Investments's biggest Q4 2020 reduction was OraSure Technologies, cutting an estimated $24.8M.
  • RTW Investments fully exited MyoKardia, Inc. Common Stock in Q4 2020, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 48% of its $5.96B portfolio in Q4 2020.
  • RTW Investments opened 25 new positions and closed 14 in Q4 2020.
  • RTW Investments's portfolio value rose 44% quarter-over-quarter to $5.96B.

Based on RTW Investments's 13F filing for Q4 2020, filed 16 Feb 2021.