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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+52.01%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$3.55B
AUM Growth
+$1.23B
Cap. Flow
+$396M
Cap. Flow %
11.15%
Top 10 Hldgs %
48.38%
Holding
82
New
17
Increased
31
Reduced
8
Closed
5

Sector Composition

Rank Sector Weight
1 Healthcare 91.43%
2 Materials 0.35%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
ABUS icon
51
Arbutus Biopharma
ABUS
$915M
$12.5M 0.35%
6,869,281
AMRS
52
DELISTED
Amyris Inc.
AMRS
$12.4M 0.35%
+3,103,535
New +$10.3M
RGNX icon
53
Regenxbio
RGNX
$708M
$11.6M 0.33%
316,028
+2,422
+0.8% +$90.3K
LJPC
54
DELISTED
La Jolla Pharmaceutical Company
LJPC
$10.1M 0.28%
2,374,952
+20,218
+0.9% +$123K
TMDX icon
55
Transmedics
TMDX
$2.91B
$9.02M 0.25%
503,266
ITMR
56
DELISTED
Itamar Medical Ltd. American Depository Shares
ITMR
$8.5M 0.24%
457,218
CLSD
57
DELISTED
Clearside Biomedical
CLSD
$7.37M 0.21%
261,175
+2,276
+0.9% +$67K
ARGX icon
58
argenx
ARGX
$54.1B
$7.15M 0.2%
31,752
QURE icon
59
uniQure
QURE
$3.22B
$7.09M 0.2%
157,282
+1,206
+0.8% +$71.2K
INMD icon
60
InMode
INMD
$880M
$7.08M 0.2%
500,000
RPTX
61
DELISTED
Repare Therapeutics
RPTX
$6.98M 0.2%
+225,000
New +$7.22M
BWAY
62
Brainsway
BWAY
$622M
$6.56M 0.18%
2,214,840
ARVN icon
63
Arvinas
ARVN
$572M
$5.84M 0.16%
174,118
-170,819
-50% -$7.25M
ARYBU
64
DELISTED
ARYA Sciences Acquisition Corp II Unit
ARYBU
$5.8M 0.16%
+500,000
New +$5.5M
LSACU
65
DELISTED
LifeSci Acquisition Corp. Unit 1 COM & 1 WT
LSACU
$5.5M 0.15%
500,000
CHAQ.U
66
DELISTED
Chardan Healthcare Acquisition 2 Corp. Units, each consisting of one share of Common Stock, and one
CHAQ.U
$3.67M 0.1%
+350,000
New +$3.51M
PHGE icon
67
BiomX
PHGE
$1.85M
$3.31M 0.09%
3,158
PSNL icon
68
Personalis
PSNL
$1.51B
$3.31M 0.09%
255,000
PROF
69
Profound Medical
PROF
$269M
$2.95M 0.08%
174,193
BIOR
70
DELISTED
Biora Therapeutics, Inc. Common Stock
BIOR
$2.48M 0.07%
+1,100
New +$3M
NARI
71
DELISTED
Inari Medical, Inc. Common Stock
NARI
$2.17M 0.06%
+44,860
New +$2.14M
FLGT icon
72
Fulgent Genetics
FLGT
$527M
$1.2M 0.03%
75,000
MOTS
73
DELISTED
Motus GI Holdings, Inc. Common Stock
MOTS
$1.02M 0.03%
2,585
TWST icon
74
Twist Bioscience
TWST
$7.25B
$837K 0.02%
18,473
+3,149
+21% +$113K
BNR
75
Burning Rock Biotech
BNR
$92.9M
$810K 0.02%
+3,000
New +$822K

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RTW Investments's Q2 2020 Portfolio in Review

As of Q2 2020, RTW Investments held 82 positions worth $3.55B, up 53% from $2.32B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $396M of net new capital in Q2 2020, opening 17 new positions and adding to 31 existing holdings. Its largest new stake was Avidity Biosciences: 3,995,000 shares worth $104M.

By sector, the portfolio is most concentrated in Healthcare at 91% of assets, down from 94% a quarter earlier, followed by Materials.

On the sell side, the largest reduction was STAAR Surgical, an estimated $15M trimmed.

  • RTW Investments's largest Q2 2020 buy was Avidity Biosciences: 3,995,000 shares worth $104M.
  • RTW Investments added most to Axsome Therapeutics in Q2 2020, an estimated $46.6M increase.
  • RTW Investments's biggest Q2 2020 reduction was STAAR Surgical, cutting an estimated $15M.
  • RTW Investments fully exited Bristol-Myers Squibb in Q2 2020, selling an estimated $94M.
  • RTW Investments's ten largest holdings make up 48% of its $3.55B portfolio in Q2 2020.
  • RTW Investments opened 17 new positions and closed 5 in Q2 2020.
  • RTW Investments's portfolio value rose 53% quarter-over-quarter to $3.55B.

Based on RTW Investments's 13F filing for Q2 2020, filed 14 Aug 2020.