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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-24.91%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$1.09B
AUM Growth
-$580M
Cap. Flow
-$124M
Cap. Flow %
-11.41%
Top 10 Hldgs %
62.53%
Holding
60
New
14
Increased
22
Reduced
10
Closed
12

Top Buys

Rank Stock Value
1
QTTB icon
Q32 Bio
QTTB
+$25.2M
2
ADVM
Adverum Biotechnologies
ADVM
+$24.7M
3
SAGE
Sage Therapeutics
SAGE
+$19M
4
RCKT icon
Rocket Pharmaceuticals
RCKT
+$17.7M
5
ASMB icon
Assembly Biosciences
ASMB
+$16.6M

Top Sells

Rank Stock Value
1
PRQR icon
ProQR Therapeutics
PRQR
+$60.4M
2
PTCT icon
PTC Therapeutics
PTCT
+$48.7M
3
CORI
Corium International, Inc.
CORI
+$34.3M
4
ARWR icon
Arrowhead Research
ARWR
+$31.3M
5
ILMN icon
Illumina
ILMN
+$30.3M

Sector Composition

Rank Sector Weight
1 Healthcare 91.62%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NVAX icon
51
Novavax
NVAX
$1.27B
– –
-138,551
Closed -$5.21M
PACB icon
52
Pacific Biosciences
PACB
$404M
– –
-2,237,607
Closed -$12.1M
QGEN icon
53
Qiagen
QGEN
$8.65B
– –
-731,174
Closed -$29.4M
RMD icon
54
ResMed
RMD
$32.5B
– –
-147,400
Closed -$17M
VKTX icon
55
Viking Therapeutics
VKTX
$3.91B
– –
-500,000
Closed -$8.71M
BLCM
56
DELISTED
Bellicum Pharmaceuticals, Inc.
BLCM
– –
-15,749
Closed -$970K
NVTR
57
DELISTED
Nuvectra Corporation Common Stock
NVTR
– –
-251,329
Closed -$5.52M
CORI
58
DELISTED
Corium International, Inc.
CORI
– –
-3,610,632
Closed -$34.3M
1 2
3

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RTW Investments's Q4 2018 Portfolio in Review

As of Q4 2018, RTW Investments held 60 positions worth $1.09B, down 35% from $1.67B the previous quarter. Its ten largest holdings account for 63% of the portfolio.

RTW Investments withdrew a net $124M in Q4 2018, closing 12 positions and reducing 10 holdings. Its most notable exit was Corium International, Inc., an estimated $34.3M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, down from 93% a quarter earlier.

Against the trend, RTW Investments opened a new position in Sage Therapeutics worth $15.9M.

  • RTW Investments's largest Q4 2018 buy was Sage Therapeutics: 165,990 shares worth $15.9M.
  • RTW Investments added most to Q32 Bio in Q4 2018, an estimated $25.2M increase.
  • RTW Investments's biggest Q4 2018 reduction was ProQR Therapeutics, cutting an estimated $60.4M.
  • RTW Investments fully exited Corium International, Inc. in Q4 2018, selling an estimated $34.3M.
  • RTW Investments's ten largest holdings make up 63% of its $1.09B portfolio in Q4 2018.
  • RTW Investments opened 14 new positions and closed 12 in Q4 2018.
  • RTW Investments's portfolio value fell 35% quarter-over-quarter to $1.09B.

Based on RTW Investments's 13F filing for Q4 2018, filed 14 Feb 2019.