RI

RTW Investments Portfolio holdings

AUM $7.02B
1-Year Return 28.16%
This Quarter Return
+18.13%
1 Year Return
+28.16%
3 Year Return
+245.48%
5 Year Return
+425.65%
10 Year Return
+5,642.23%
AUM
$4.9B
AUM Growth
+$561M
Cap. Flow
+$300M
Cap. Flow %
6.12%
Top 10 Hldgs %
55.22%
Holding
87
New
1
Increased
20
Reduced
10
Closed
10

Top Buys

1
AXSM icon
Axsome Therapeutics
AXSM
$84.7M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
$79.8M
3
RARE icon
Ultragenyx Pharmaceutical
RARE
$74.4M
4
IMCR icon
Immunocore
IMCR
$63.2M
5
RCKT icon
Rocket Pharmaceuticals
RCKT
$36.9M

Top Sells

1
ISEE
IVERIC bio, Inc. Common Stock
ISEE
$60M
2
TSVT
2seventy bio
TSVT
$17.9M
3
TNDM icon
Tandem Diabetes Care
TNDM
$15.4M
4
GH icon
Guardant Health
GH
$8.02M
5
RCOR
Renovacor, Inc.
RCOR
$7.56M

Sector Composition

1 Healthcare 99.63%
2 Financials 0.27%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
AVDL
26
Avadel Pharmaceuticals
AVDL
$1.46B
$41.1M 0.84%
5,741,939
– –
PTGX icon
27
Protagonist Therapeutics
PTGX
$3.71B
$39.2M 0.8%
3,591,986
-584,851
-14% -$6.38M
ACET icon
28
Adicet Bio
ACET
$59.4M
$37.9M 0.77%
4,241,472
– –
PMVP icon
29
PMV Pharmaceuticals
PMVP
$76.3M
$37.9M 0.77%
4,356,920
– –
TARS icon
30
Tarsus Pharmaceuticals
TARS
$2.42B
$37.4M 0.76%
2,548,125
+524,946
+26% +$7.7M
BCYC
31
Bicycle Therapeutics
BCYC
$483M
$37.3M 0.76%
1,258,587
-17,689
-1% -$524K
FULC icon
32
Fulcrum Therapeutics
FULC
$372M
$36.4M 0.74%
4,993,279
+1,007,369
+25% +$7.33M
STOK icon
33
Stoke Therapeutics
STOK
$1.08B
$35.7M 0.73%
3,870,981
+219,158
+6% +$2.02M
TXG icon
34
10x Genomics
TXG
$1.69B
$31.8M 0.65%
872,592
+232,938
+36% +$8.49M
OYST
35
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$25.7M 0.53%
2,304,977
+260,665
+13% +$2.91M
OLK
36
DELISTED
Olink Holding AB (publ) American Depositary Shares
OLK
$24.9M 0.51%
981,918
– –
OM icon
37
Outset Medical
OM
$237M
$23.5M 0.48%
60,643
– –
GHRS icon
38
GH Research
GHRS
$872M
$21.1M 0.43%
2,168,957
– –
ISEE
39
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$17.6M 0.36%
821,288
-2,803,712
-77% -$60M
MIST icon
40
Milestone Pharmaceuticals
MIST
$151M
$17.1M 0.35%
4,315,102
– –
CINC
41
DELISTED
CinCor Pharma, Inc. Common Stock
CINC
$17.1M 0.35%
1,389,705
– –
CCCC icon
42
C4 Therapeutics
CCCC
$190M
$16.6M 0.34%
2,819,472
– –
ALLK
43
DELISTED
Allakos
ALLK
$13.8M 0.28%
1,643,500
– –
CSTL icon
44
Castle Biosciences
CSTL
$670M
$12.2M 0.25%
516,995
– –
GH icon
45
Guardant Health
GH
$7.65B
$11.7M 0.24%
430,887
-295,000
-41% -$8.02M
TERN icon
46
Terns Pharmaceuticals
TERN
$618M
$10.2M 0.21%
+1,000,000
New +$10.2M
OBIO icon
47
Orchestra BioMed
OBIO
$148M
$9.98M 0.2%
1,000,000
– –
WHWK
48
Whitehawk Therapeutics, Inc. Common Stock
WHWK
$85.3M
$9.81M 0.2%
764,701
– –
GLUE icon
49
Monte Rosa Therapeutics
GLUE
$303M
$9.24M 0.19%
1,214,572
– –
SGHT icon
50
Sight Sciences
SGHT
$195M
$8.12M 0.17%
665,323
– –
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