We are live on ! Find out more
RI

RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+60.02%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$5.96B
AUM Growth
+$1.81B
Cap. Flow
+$286M
Cap. Flow %
4.79%
Top 10 Hldgs %
47.57%
Holding
116
New
25
Increased
35
Reduced
12
Closed
14

Top Buys

Rank Stock Value
1
GMED icon
Globus Medical
GMED
+$94.3M
2
TARS icon
Tarsus Pharmaceuticals
TARS
+$70.2M
3
CCCC icon
C4 Therapeutics
CCCC
+$62.3M
4
ARVN icon
Arvinas
ARVN
+$61.8M
5
ILMN icon
Illumina
ILMN
+$61.2M

Top Sells

Rank Stock Value
1
MYOK
MyoKardia, Inc. Common Stock
MYOK
+$128M
2
BAX icon
Baxter International
BAX
+$86.6M
3
INCY icon
Incyte
INCY
+$30M
4
QTTB icon
Q32 Bio
QTTB
+$26.9M
5
OSUR icon
OraSure Technologies
OSUR
+$24.8M

Sector Composition

Rank Sector Weight
1 Healthcare 94%
2 Financials 0.18%
3 Materials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
LUNG icon
26
Pulmonx
LUNG
$87.6M
$74.8M 1.26%
+1,129,600
New +$55.3M
PTGX icon
27
Protagonist Therapeutics
PTGX
$9.44B
$73.6M 1.23%
3,650,069
+241,108
+7% +$5.19M
CCCC icon
28
C4 Therapeutics
CCCC
$412M
$68.7M 1.15%
+2,149,228
New +$62.3M
TNDM icon
29
Tandem Diabetes Care
TNDM
$1.56B
$63.2M 1.06%
660,982
+57,501
+10% +$5.93M
CLDX icon
30
Celldex Therapeutics
CLDX
$3.28B
$60M 1.01%
3,422,855
+302,718
+10% +$5.45M
KURA icon
31
Kura Oncology
KURA
$850M
$55.6M 0.93%
+1,701,781
New +$59.8M
TBIO
32
DELISTED
Translate Bio, Inc. Common Stock
TBIO
$54.9M 0.92%
2,978,427
-766,859
-20% -$13.7M
NSTG
33
DELISTED
NanoString Technologies, Inc.
NSTG
$53.8M 0.9%
804,029
-143,105
-15% -$7.18M
CSTL icon
34
Castle Biosciences
CSTL
$979M
$53.7M 0.9%
799,009
+55,367
+7% +$3M
RLMD icon
35
Relmada Therapeutics
RLMD
$527M
$48.5M 0.81%
1,512,673
+1,336
+0.1% +$45.9K
ISEE
36
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$46.5M 0.78%
6,722,624
+59,185
+0.9% +$379K
FPRX
37
DELISTED
Five Prime Therapeutics, Inc.
FPRX
$42.8M 0.72%
+2,515,788
New +$31.5M
CYTK icon
38
Cytokinetics
CYTK
$10.4B
$41.3M 0.69%
2,000,000
– –
AGEN
39
Agenus
AGEN
$290M
$40.9M 0.69%
655,455
– –
OYST
40
DELISTED
Oyster Point Pharma, Inc. Common Stock
OYST
$36.2M 0.61%
1,925,594
+1,701
+0.1% +$36.7K
AVDL
41
DELISTED
Avadel Pharmaceuticals
AVDL
$36M 0.6%
5,387,513
+20,808
+0.4% +$130K
ITOS
42
DELISTED
iTeos Therapeutics
ITOS
$36M 0.6%
1,074,166
+171,311
+19% +$4.54M
OM icon
43
Outset Medical
OM
$90.8M
$33.3M 0.56%
39,005
+12,005
+44% +$9.25M
TRIL
44
DELISTED
Trillium Therapeutics Inc.
TRIL
$31.9M 0.53%
2,165,197
+4,397
+0.2% +$63.4K
PMVP icon
45
PMV Pharmaceuticals
PMVP
$63.5M
$30.8M 0.52%
500,882
+882
+0.2% +$34.6K
CRIS icon
46
Curis
CRIS
$7.83M
$30.5M 0.51%
+9,318
New +$11.2M
CELL
47
DELISTED
PhenomeX Inc. Common Stock
CELL
$29M 0.49%
324,734
+24,396
+8% +$2.05M
MIST icon
48
Milestone Pharmaceuticals
MIST
$152M
$28.9M 0.49%
4,315,102
– –
MGNX icon
49
MacroGenics
MGNX
$257M
$28.7M 0.48%
1,256,409
+1,110
+0.1% +$25.6K
IDYA icon
50
IDEAYA Biosciences
IDYA
$3.56B
$25.9M 0.43%
+1,846,843
New +$25M
1
2
3 4 5

Similar funds

HRCM
Hood River Capital Management Palm Beach Gardens, Florida $9.98B AUM 145.42% 1-Year Est. Return
RA
Royce & Associates New York $10.1B AUM 42.88% 1-Year Est. Return
GI
GAMCO Investors Greenwich, Connecticut $10.2B AUM 30.27% 1-Year Est. Return
IIM
INTECH Investment Management West Palm Beach, Florida $10.2B AUM 28.14% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
VPIM
Vanguard Personalized Indexing Management Oakland, California $10.2B AUM 34.45% 1-Year Est. Return
HI
HBK Investments Dallas, Texas $9.85B AUM 55.6% 1-Year Est. Return
MF
Magnetar Financial Evanston, Illinois $9.84B AUM 190.63% 1-Year Est. Return

RTW Investments's Q4 2020 Portfolio in Review

As of Q4 2020, RTW Investments held 116 positions worth $5.96B, up 44% from $4.15B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $286M of net new capital in Q4 2020, opening 25 new positions and adding to 35 existing holdings. Its largest new stake was Globus Medical: 1,640,859 shares worth $107M.

By sector, the portfolio is most concentrated in Healthcare at 94% of assets, up from 93% a quarter earlier, followed by Financials and Materials.

On the sell side, the largest reduction was OraSure Technologies, an estimated $24.8M trimmed.

  • RTW Investments's largest Q4 2020 buy was Globus Medical: 1,640,859 shares worth $107M.
  • RTW Investments added most to Illumina in Q4 2020, an estimated $61.2M increase.
  • RTW Investments's biggest Q4 2020 reduction was OraSure Technologies, cutting an estimated $24.8M.
  • RTW Investments fully exited MyoKardia, Inc. Common Stock in Q4 2020, selling an estimated $128M.
  • RTW Investments's ten largest holdings make up 48% of its $5.96B portfolio in Q4 2020.
  • RTW Investments opened 25 new positions and closed 14 in Q4 2020.
  • RTW Investments's portfolio value rose 44% quarter-over-quarter to $5.96B.

Based on RTW Investments's 13F filing for Q4 2020, filed 16 Feb 2021.