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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
+52.01%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$3.55B
AUM Growth
+$1.23B
Cap. Flow
+$396M
Cap. Flow %
11.15%
Top 10 Hldgs %
48.38%
Holding
82
New
17
Increased
31
Reduced
8
Closed
5

Top Buys

Rank Stock Value
1
RNAM
Avidity Biosciences
RNAM
+$115M
2
BAX icon
Baxter International
BAX
+$84.4M
3
CERN
Cerner Corp
CERN
+$81.3M
4
AXSM icon
Axsome Therapeutics
AXSM
+$46.6M
5
TXG icon
10x Genomics
TXG
+$34.7M

Top Sells

Rank Stock Value
1
BMY icon
Bristol-Myers Squibb
BMY
+$94M
2
ZBH icon
Zimmer Biomet
ZBH
+$67.9M
3
SRPT icon
Sarepta Therapeutics
SRPT
+$51.8M
4
GBT
Global Blood Therapeutics, Inc.
GBT
+$36.8M
5
STAA icon
STAAR Surgical
STAA
+$15M

Sector Composition

Rank Sector Weight
1 Healthcare 91.43%
2 Materials 0.35%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
AGEN
26
Agenus
AGEN
$312M
$50.6M 1.42%
655,455
-11,818
-2% -$708K
KRRO icon
27
Korro Bio
KRRO
$178M
$50.3M 1.41%
43,230
+1,806
+4% +$1.63M
ESTA icon
28
Establishment Labs
ESTA
$2.33B
$43.3M 1.22%
2,319,138
– –
AVDL
29
DELISTED
Avadel Pharmaceuticals
AVDL
$42.9M 1.21%
5,306,570
+690,000
+15% +$6.08M
DMTK
30
DELISTED
DermTech, Inc. Common Stock
DMTK
$37.8M 1.06%
2,855,765
+255,036
+10% +$3.32M
MGNX icon
31
MacroGenics
MGNX
$255M
$34.8M 0.98%
+1,245,816
New +$21.6M
CLDX icon
32
Celldex Therapeutics
CLDX
$3.26B
$33.9M 0.95%
+2,610,000
New +$11.6M
ISEE
33
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
$33.6M 0.95%
+6,596,536
New +$27.5M
CSTL icon
34
Castle Biosciences
CSTL
$931M
$30.3M 0.85%
803,510
+105,392
+15% +$3.6M
PRQR icon
35
ProQR Therapeutics
PRQR
$268M
$29.8M 0.84%
4,902,785
+123,650
+3% +$668K
NSTG
36
DELISTED
NanoString Technologies, Inc.
NSTG
$27.8M 0.78%
947,134
-112,487
-11% -$3.35M
ADAP
37
DELISTED
Adaptimmune Therapeutics
ADAP
$26M 0.73%
+2,600,000
New +$16.3M
WVE icon
38
Wave Life Sciences
WVE
$1.19B
$24.9M 0.7%
2,390,496
-999,437
-29% -$9.4M
ODT
39
DELISTED
Odonate Therapeutics, Inc. Common Stock
ODT
$20.4M 0.57%
481,027
+114,942
+31% +$3.72M
STAA icon
40
STAAR Surgical
STAA
$1.15B
$19M 0.53%
308,904
-366,746
-54% -$15M
APYX icon
41
Apyx Medical
APYX
$175M
$18.8M 0.53%
3,391,279
– –
OSUR icon
42
OraSure Technologies
OSUR
$275M
$17.9M 0.5%
+1,540,972
New +$20M
JNJ icon
43
Johnson & Johnson
JNJ
$619B
$17.8M 0.5%
126,858
+10,000
+9% +$1.46M
TELA icon
44
TELA Bio
TELA
$38.5M
$17.7M 0.5%
1,364,358
+225,000
+20% +$2.96M
MIST icon
45
Milestone Pharmaceuticals
MIST
$147M
$16.3M 0.46%
4,315,102
– –
XGN icon
46
Exagen
XGN
$160M
$15.6M 0.44%
1,255,131
-509
-0% -$6.89K
MDXG icon
47
MiMedx Group
MDXG
$609M
$14.6M 0.41%
2,700,320
– –
NEO icon
48
NeoGenomics
NEO
$2B
$13.8M 0.39%
+445,000
New +$12.3M
GNMK
49
DELISTED
GenMark Diagnostics, Inc
GNMK
$13.8M 0.39%
+935,206
New +$9.5M
CTMX icon
50
CytomX Therapeutics
CTMX
$734M
$12.6M 0.35%
1,514,476
+447,685
+42% +$4.16M
1
2
3 4

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RTW Investments's Q2 2020 Portfolio in Review

As of Q2 2020, RTW Investments held 82 positions worth $3.55B, up 53% from $2.32B the previous quarter. Its ten largest holdings account for 48% of the portfolio.

RTW Investments deployed $396M of net new capital in Q2 2020, opening 17 new positions and adding to 31 existing holdings. Its largest new stake was Avidity Biosciences: 3,995,000 shares worth $104M.

By sector, the portfolio is most concentrated in Healthcare at 91% of assets, down from 94% a quarter earlier, followed by Materials.

On the sell side, the largest reduction was STAAR Surgical, an estimated $15M trimmed.

  • RTW Investments's largest Q2 2020 buy was Avidity Biosciences: 3,995,000 shares worth $104M.
  • RTW Investments added most to Axsome Therapeutics in Q2 2020, an estimated $46.6M increase.
  • RTW Investments's biggest Q2 2020 reduction was STAAR Surgical, cutting an estimated $15M.
  • RTW Investments fully exited Bristol-Myers Squibb in Q2 2020, selling an estimated $94M.
  • RTW Investments's ten largest holdings make up 48% of its $3.55B portfolio in Q2 2020.
  • RTW Investments opened 17 new positions and closed 5 in Q2 2020.
  • RTW Investments's portfolio value rose 53% quarter-over-quarter to $3.55B.

Based on RTW Investments's 13F filing for Q2 2020, filed 14 Aug 2020.