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RTW Investments Portfolio holdings

AUM $10B
1-Year Est. Return 135.35%
This Fund
S&P 500
This Quarter Est. Return
-18.55%
1 Year Est. Return
+135.35%
3 Year Est. Return
+383.62%
5 Year Est. Return
+523.94%
10 Year Est. Return
+15,981.64%
AUM
$322M
AUM Growth
-$21.7M
Cap. Flow
+$85.5M
Cap. Flow %
26.57%
Top 10 Hldgs %
71.05%
Holding
50
New
17
Increased
16
Reduced
6
Closed
5

Top Buys

Rank Stock Value
1
LJPC
La Jolla Pharmaceutical Company
LJPC
+$25.1M
2
MRTX
Mirati Therapeutics, Inc. Common Stock
MRTX
+$14.6M
3
ALNY icon
Alnylam Pharmaceuticals
ALNY
+$13.6M
4
ATRA icon
Atara Biotherapeutics
ATRA
+$12.8M
5
INCY icon
Incyte
INCY
+$12.1M

Top Sells

Rank Stock Value
1
DYAX
DYAX CORPORATION
DYAX
+$10.6M
2
TLT icon
iShares 20+ Year Treasury Bond ETF
TLT
+$3.88M
3
LUMO
Lumos Pharma, Inc. Common Stock
LUMO
+$3.5M
4
ARWR icon
Arrowhead Research
ARWR
+$2.91M
5
USO icon
United States Oil Fund
USO
+$2.53M

Sector Composition

Rank Sector Weight
1 Healthcare 84.35%
2 Financials 0%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
GYRE icon
26
Gyre Therapeutics
GYRE
$686M
$1.77M 0.55%
3,385
– –
RPRX
27
DELISTED
Repros Therapeutics Inc.
RPRX
$1.73M 0.54%
232,830
+3,466
+2% +$26.5K
VBIV
28
DELISTED
VBI Vaccines, Inc. New Common Stock (Canada)
VBIV
$1.72M 0.53%
+21,667
New +$1.72M
OSUR icon
29
OraSure Technologies
OSUR
$287M
$1.43M 0.45%
+322,996
New +$1.69M
CYTR
30
DELISTED
CytRx Corp
CYTR
$1.07M 0.33%
75,578
+1,126
+2% +$19.1K
LUMO
31
DELISTED
Lumos Pharma, Inc. Common Stock
LUMO
$1.01M 0.32%
3,143
-7,968
-72% -$3.5M
MASI
32
DELISTED
Masimo
MASI
$999K 0.31%
+25,900
New +$1.06M
MDRX
33
DELISTED
Veradigm Inc. Common Stock
MDRX
$595K 0.18%
+48,000
New +$661K
BCRX icon
34
CALL
BioCryst Pharmaceuticals
BCRX
$2.29B
$431K 0.13%
+2,000
New +$26.7K
ALPN
35
DELISTED
Alpine Immune Sciences Inc
ALPN
$389K 0.12%
7,500
– –
TMBR
36
DELISTED
Timber Pharmaceuticals, Inc.
TMBR
$382K 0.12%
25
– –
NTRA icon
37
Natera
NTRA
$39.4B
$344K 0.11%
+31,693
New +$537K
GHDX
38
DELISTED
Genomic Health, Inc.
GHDX
$317K 0.1%
+15,000
New +$387K
ELGX
39
DELISTED
Endologix Inc
ELGX
$184K 0.06%
+1,500
New +$204K
VCYT icon
40
Veracyte
VCYT
$3.73B
$117K 0.04%
+25,000
New +$238K
ADAP
41
DELISTED
Adaptimmune Therapeutics
ADAP
$84K 0.03%
7,028
-12,972
-65% -$183K
VIVO
42
CALL
DELISTED
Meridian Bioscience Inc
VIVO
$50K 0.02%
+1,252
New +$22.9K
USO icon
43
CALL
United States Oil Fund
USO
$1.81B
$42K 0.01%
+1,731
New +$213K
BRK.B icon
44
Berkshire Hathaway Class B
BRK.B
$1.12T
$7K ﹤0.01%
50
– –
BHC icon
45
CALL
Bausch Health
BHC
$2.41B
– –
0
– -$78K
FBIO icon
46
Fortress Biotech
FBIO
$90.4M
– –
-794
Closed -$40K
TLT icon
47
iShares 20+ Year Treasury Bond ETF
TLT
$41.7B
– –
-33,000
Closed -$3.88M
USO icon
48
United States Oil Fund
USO
$1.81B
– –
-20,625
Closed -$2.53M
ZGNX
49
DELISTED
Zogenix, Inc.
ZGNX
– –
-14,266
Closed -$192K
1
2

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RTW Investments's Q3 2015 Portfolio in Review

As of Q3 2015, RTW Investments held 50 positions worth $322M, down 6.3% from $344M the previous quarter. Its ten largest holdings account for 71% of the portfolio.

RTW Investments deployed $85.5M of net new capital in Q3 2015, opening 17 new positions and adding to 16 existing holdings. Its largest new stake was Mirati Therapeutics, Inc. Common Stock: 482,069 shares worth $16.6M.

By sector, the portfolio is most concentrated in Healthcare at 84% of assets, up from 72% a quarter earlier, followed by Financials.

On the sell side, the largest reduction was DYAX CORPORATION, an estimated $10.6M trimmed.

  • RTW Investments's largest Q3 2015 buy was Mirati Therapeutics, Inc. Common Stock: 482,069 shares worth $16.6M.
  • RTW Investments added most to La Jolla Pharmaceutical Company in Q3 2015, an estimated $25.1M increase.
  • RTW Investments's biggest Q3 2015 reduction was DYAX CORPORATION, cutting an estimated $10.6M.
  • RTW Investments fully exited iShares 20+ Year Treasury Bond ETF in Q3 2015, selling an estimated $3.88M.
  • RTW Investments's ten largest holdings make up 71% of its $322M portfolio in Q3 2015.
  • RTW Investments opened 17 new positions and closed 5 in Q3 2015.
  • RTW Investments's portfolio value fell 6.3% quarter-over-quarter to $322M.

Based on RTW Investments's 13F filing for Q3 2015, filed 13 Nov 2015.