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PAI

Palo Alto Investors Portfolio holdings

AUM $654M
1-Year Est. Return 77.8%
This Fund
S&P 500
This Quarter Est. Return
+32.15%
1 Year Est. Return
+77.8%
3 Year Est. Return
+127.05%
5 Year Est. Return
+199.24%
10 Year Est. Return
+2,229.57%
AUM
$2.4B
AUM Growth
+$519M
Cap. Flow
+$109M
Cap. Flow %
4.53%
Top 10 Hldgs %
68.89%
Holding
38
New
2
Increased
14
Reduced
2
Closed
1

Sector Composition

Rank Sector Weight
1 Healthcare 89.23%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
GILD icon
26
Gilead Sciences
GILD
$168B
$11.4M 0.48%
175,900
RIGL icon
27
Rigel Pharmaceuticals
RIGL
$782M
$10.2M 0.43%
398,595
DRNA
28
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$7.34M 0.31%
500,913
ALIM
29
DELISTED
Alimera Sciences
ALIM
$3.19M 0.13%
200,920
ZGNX
30
DELISTED
Zogenix, Inc.
ZGNX
$1.62M 0.07%
29,500
VIRX
31
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$1.41M 0.06%
33,214
CYTK icon
32
Cytokinetics
CYTK
$10.5B
$1M 0.04%
123,686
MRNS
33
DELISTED
Marinus Pharmaceuticals, Inc
MRNS
$477K 0.02%
+28,555
New +$411K
SPHS
34
DELISTED
Sophiris Bio, Inc.
SPHS
$245K 0.01%
247,000
ACGN
35
DELISTED
Aceragen Inc
ACGN
$196K 0.01%
4,537
MLNT
36
DELISTED
Melinta Therapeutics, Inc. Common Stock
MLNT
$36K ﹤0.01%
10,137
-1
-0% -$5
OCGN icon
37
Ocugen
OCGN
$475M
$35K ﹤0.01%
5,049
SHPG
38
DELISTED
Shire pic
SHPG
-47,938
Closed -$8.34M

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Palo Alto Investors's Q1 2019 Portfolio in Review

As of Q1 2019, Palo Alto Investors held 38 positions worth $2.4B, up 28% from $1.88B the previous quarter. Its ten largest holdings account for 69% of the portfolio.

Palo Alto Investors deployed $109M of net new capital in Q1 2019, opening 2 new positions and adding to 14 existing holdings. Its largest new stake was Kaleido Biosciences, Inc. Common Stock: 866,666 shares worth $12.6M.

By sector, the portfolio is most concentrated in Healthcare at 89% of assets, down from 91% a quarter earlier.

On the sell side, the largest reduction was Celgene Corp, an estimated $23.3M trimmed.

  • Palo Alto Investors's largest Q1 2019 buy was Kaleido Biosciences, Inc. Common Stock: 866,666 shares worth $12.6M.
  • Palo Alto Investors added most to Aimmune Therapeutics in Q1 2019, an estimated $55.6M increase.
  • Palo Alto Investors's biggest Q1 2019 reduction was Celgene Corp, cutting an estimated $23.3M.
  • Palo Alto Investors fully exited Shire pic in Q1 2019, selling an estimated $8.34M.
  • Palo Alto Investors's ten largest holdings make up 69% of its $2.4B portfolio in Q1 2019.
  • Palo Alto Investors opened 2 new positions and closed 1 in Q1 2019.
  • Palo Alto Investors's portfolio value rose 28% quarter-over-quarter to $2.4B.

Based on Palo Alto Investors's 13F filing for Q1 2019, filed 15 May 2019.