PAI
Palo Alto Investors Portfolio holdings
AUM
$470M
This Quarter Return
-15.62%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$1.19B
AUM Growth
+$1.19B
(-34%)
Cap. Flow
-$255M
Cap. Flow
% of AUM
-21.34%
Top 10 Holdings %
Top 10 Hldgs %
72.62%
Holding
40
New
3
Increased
3
Reduced
19
Closed
3
Top Buys
| 1 |
RVNC
Revance Therapeutics, Inc.
RVNC
|
$7.8M |
| 2 |
Syndax Pharmaceuticals
SNDX
|
$725K |
| 3 |
Travere Therapeutics
TVTX
|
$686K |
| 4 |
UroGen Pharma
URGN
|
$437K |
| 5 |
Puma Biotechnology
PBYI
|
$397K |
Top Sells
| 1 |
WMGI
Wright Medical Group Inc
WMGI
|
$63.6M |
| 2 |
BioMarin Pharmaceuticals
BMRN
|
$40.3M |
| 3 |
United Therapeutics
UTHR
|
$39.1M |
| 4 |
ALXN
Alexion Pharmaceuticals Inc
ALXN
|
$21.2M |
| 5 |
STAAR Surgical
STAA
|
$16.1M |
Sector Composition
| 1 | Healthcare | 87.96% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
|
1
BioMarin Pharmaceuticals
BMRN
$11.2B
| $130M | 10.93% | 1,544,163 -476,973 | -24% | -$40.3M |
|
|
2
STAAR Surgical
STAA
$1.36B
| $106M | 8.86% | 3,278,523 -500,415 | -13% | -$16.1M |
|
3
Insmed
INSM
$28.8B
| $97.1M | 8.13% | 6,055,623 -793,137 | -12% | -$12.7M |
|
|
EPZM
4
DELISTED
Epizyme, Inc
EPZM
| $86.1M | 7.21% | 5,551,803 -594,142 | -10% | -$9.22M |
|
|
5
United Therapeutics
UTHR
$13.8B
| $83.1M | 6.96% | 876,575 -412,327 | -32% | -$39.1M |
|
6
Karyopharm Therapeutics
KPTI
$61.7M
| $82.6M | 6.92% | 4,299,901 -295,100 | -6% | -$5.67M |
|
|
ABMD
7
DELISTED
Abiomed Inc
ABMD
| $73M | 6.11% | 502,745 -61,423 | -11% | -$8.92M |
|
|
IMMU
8
DELISTED
Immunomedics Inc
IMMU
| $71.3M | 5.97% | 5,290,746 -632,449 | -11% | -$8.53M |
|
9
Acadia Pharmaceuticals
ACAD
$4.38B
| $68.9M | 5.77% | 1,631,524 -273,850 | -14% | -$11.6M |
|
10
Amicus Therapeutics
FOLD
$2.34B
| $68.8M | 5.76% | 7,447,618 +33,698 | +0.5% | +$311K |
|
|
ALXN
11
DELISTED
Alexion Pharmaceuticals Inc
ALXN
| $57.7M | 4.83% | 642,491 -235,609 | -27% | -$21.2M |
|
|
AIMT
12
DELISTED
Aimmune Therapeutics, Inc.
AIMT
| $47.5M | 3.98% | 3,295,712 -84,729 | -3% | -$1.22M |
|
13
Vanda Pharmaceuticals
VNDA
$279M
| $42.8M | 3.59% | 4,134,846 -390,630 | -9% | -$4.05M |
|
|
MNTA
14
DELISTED
Momenta Pharmaceuticals, Inc.
MNTA
| $41.6M | 3.48% | 1,527,956 -157,416 | -9% | -$4.28M |
|
|
CLVS
15
DELISTED
Clovis Oncology, Inc.
CLVS
| $29.5M | 2.47% | 4,635,789 -420,497 | -8% | -$2.67M |
|
|
AMAG
16
DELISTED
AMAG Pharmaceuticals, Inc.
AMAG
| $18.6M | 1.55% | 3,002,748 -41,626 | -1% | -$257K |
|
|
SAGE
17
DELISTED
Sage Therapeutics
SAGE
| $16.8M | 1.41% | 586,674 -66,920 | -10% | -$1.92M |
|
18
Align Technology
ALGN
$10.3B
| $13.3M | 1.11% | 76,205 -51,300 | -40% | -$8.92M |
|
|
19
Puma Biotechnology
PBYI
$254M
| $11.8M | 0.99% | 1,396,163 +46,983 | +3% | +$397K |
|
|
RVNC
20
DELISTED
Revance Therapeutics, Inc.
RVNC
| $9.11M | 0.76% | 615,705 +527,115 | +595% | +$7.8M |
|
21
Prothena Corp
PRTA
$441M
| $8.3M | 0.69% | 775,296 -217,453 | -22% | -$2.33M |
|
|
WMGI
22
DELISTED
Wright Medical Group Inc
WMGI
| $6.96M | 0.58% | 242,940 -2,220,115 | -90% | -$63.6M |
|
|
DRNA
23
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
| $6.1M | 0.51% | 331,813 | – | – |
|
24
Rigel Pharmaceuticals
RIGL
$697M
| $5.53M | 0.46% | 3,542,551 | – | – |
|
|
KLDO
25
DELISTED
Kaleido Biosciences, Inc. Common Stock
KLDO
| $4.85M | 0.41% | 787,999 | – | – |
|