PAI
Palo Alto Investors Portfolio holdings
AUM $470M
1-Year Return
2.57%
This Quarter Return
-9.48%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$2.06B
AUM Growth
-$340M
(-14%)
Cap. Flow
-$49.1M
Cap. Flow
% of AUM
-2.38%
Top 10 Holdings %
Top 10 Hldgs %
68.62%
Holding
39
New
2
Increased
10
Reduced
9
Closed
–
Top Buys
| 1 |
Insmed
INSM
|
+$6.07M |
| 2 |
IMMU
Immunomedics Inc
IMMU
|
+$4.09M |
| 3 |
Puma Biotechnology
PBYI
|
+$2.86M |
| 4 |
Amicus Therapeutics
FOLD
|
+$2.2M |
| 5 |
ABMD
Abiomed Inc
ABMD
|
+$2.01M |
Top Sells
| 1 |
ALXN
Alexion Pharmaceuticals Inc
ALXN
|
+$26.9M |
| 2 |
CELG
Celgene Corp
CELG
|
+$14.7M |
| 3 |
SAGE
Sage Therapeutics
SAGE
|
+$11.5M |
| 4 |
United Therapeutics
UTHR
|
+$6.18M |
| 5 |
Align Technology
ALGN
|
+$4.9M |
Sector Composition
| 1 | Healthcare | 89.7% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
1
BioMarin Pharmaceuticals
BMRN
$10.2B
| $223M | 10.85% |
2,606,485
-35,000
| -1% | -$3M |
|
|
2
Insmed
INSM
$30.3B
| $202M | 9.82% |
7,890,917
+237,300
| +3% | +$6.07M |
|
|
ABMD
3
DELISTED
Abiomed Inc
ABMD
| $184M | 8.95% |
706,354
+7,700
| +1% | +$2.01M |
|
|
SAGE
4
DELISTED
Sage Therapeutics
SAGE
| $146M | 7.08% |
795,031
-62,650
| -7% | -$11.5M |
|
|
ALXN
5
DELISTED
Alexion Pharmaceuticals Inc
ALXN
| $134M | 6.52% |
1,023,780
-205,250
| -17% | -$26.9M |
|
6
STAAR Surgical
STAA
$1.37B
| $124M | 6.05% |
4,237,051
+18,149
| +0.4% | +$533K |
|
|
7
United Therapeutics
UTHR
$18B
| $121M | 5.89% |
1,552,792
-79,233
| -5% | -$6.18M |
|
|
8
Amicus Therapeutics
FOLD
$2.47B
| $97.3M | 4.73% |
7,796,299
+176,466
| +2% | +$2.2M |
|
|
IMMU
9
DELISTED
Immunomedics Inc
IMMU
| $92.6M | 4.5% |
6,676,755
+295,200
| +5% | +$4.09M |
|
|
EPZM
10
DELISTED
Epizyme, Inc
EPZM
| $87M | 4.23% |
6,935,074
| – | – |
|
|
WMGI
11
DELISTED
Wright Medical Group Inc
WMGI
| $82.6M | 4.02% |
2,771,394
| – | – |
|
|
AIMT
12
DELISTED
Aimmune Therapeutics, Inc.
AIMT
| $79.7M | 3.88% |
3,828,564
+79,625
| +2% | +$1.66M |
|
|
CLVS
13
DELISTED
Clovis Oncology, Inc.
CLVS
| $76.5M | 3.72% |
5,141,304
-98,000
| -2% | -$1.46M |
|
14
Vanda Pharmaceuticals
VNDA
$259M
| $71.2M | 3.46% |
5,055,050
| – | – |
|
15
Acadia Pharmaceuticals
ACAD
$4.16B
| $61.7M | 3% |
2,308,803
+60,400
| +3% | +$1.61M |
|
|
16
Align Technology
ALGN
$9.56B
| $40.4M | 1.96% |
147,505
-17,900
| -11% | -$4.9M |
|
17
Exact Sciences
EXAS
$10B
| $37.2M | 1.81% |
314,889
| – | – |
|
|
AMAG
18
DELISTED
AMAG Pharmaceuticals, Inc.
AMAG
| $33.7M | 1.64% |
3,375,506
-45,800
| -1% | -$458K |
|
19
Karyopharm Therapeutics
KPTI
$54.3M
| $31.5M | 1.53% |
350,818
| – | – |
|
|
MNTA
20
DELISTED
Momenta Pharmaceuticals, Inc.
MNTA
| $23.9M | 1.16% |
1,919,313
+77,700
| +4% | +$967K |
|
|
ALDR
21
DELISTED
Alder Biopharmaceuticals, Inc.
ALDR
| $21.9M | 1.07% |
1,861,630
| – | – |
|
|
22
Puma Biotechnology
PBYI
$234M
| $17.9M | 0.87% |
1,405,680
+224,900
| +19% | +$2.86M |
|
23
Gilead Sciences
GILD
$140B
| $11.9M | 0.58% |
175,900
| – | – |
|
24
Prothena Corp
PRTA
$439M
| $11.7M | 0.57% |
1,108,510
| – | – |
|
25
Rigel Pharmaceuticals
RIGL
$627M
| $10.4M | 0.51% |
398,595
| – | – |
|