PAI
Palo Alto Investors Portfolio holdings
AUM
$470M
This Quarter Return
+2.91%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$1.76B
AUM Growth
+$1.76B
(-8%)
Cap. Flow
-$48.3M
Cap. Flow
% of AUM
-2.75%
Top 10 Holdings %
Top 10 Hldgs %
72.57%
Holding
43
New
2
Increased
20
Reduced
8
Closed
1
Top Buys
| 1 |
eHealth
EHTH
|
$34.3M |
| 2 |
Biogen
BIIB
|
$30.5M |
| 3 |
GRTS
Gritstone bio, Inc. Common Stock
GRTS
|
$21.7M |
| 4 |
Amicus Therapeutics
FOLD
|
$18.7M |
| 5 |
RVNC
Revance Therapeutics, Inc.
RVNC
|
$14.8M |
Top Sells
| 1 |
STAAR Surgical
STAA
|
$109M |
| 2 |
ALXN
Alexion Pharmaceuticals Inc
ALXN
|
$41M |
| 3 |
United Therapeutics
UTHR
|
$16.4M |
| 4 |
Insmed
INSM
|
$9.59M |
| 5 |
Vanda Pharmaceuticals
VNDA
|
$6.59M |
Sector Composition
| 1 | Healthcare | 95.1% |
| 2 | Financials | 4.39% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
|
1
Insmed
INSM
$28.8B
| $198M | 11.3% | 5,824,507 -281,473 | -5% | -$9.59M |
|
|
2
STAAR Surgical
STAA
$1.36B
| $191M | 10.89% | 1,813,911 -1,035,437 | -36% | -$109M |
|
|
ABMD
3
DELISTED
Abiomed Inc
ABMD
| $183M | 10.45% | 575,233 +18,600 | +3% | +$5.93M |
|
4
BioMarin Pharmaceuticals
BMRN
$11.2B
| $167M | 9.49% | 2,205,750 +50,700 | +2% | +$3.83M |
|
|
5
United Therapeutics
UTHR
$13.8B
| $115M | 6.55% | 687,206 -98,200 | -13% | -$16.4M |
|
|
6
Amicus Therapeutics
FOLD
$2.34B
| $96.4M | 5.49% | 9,761,043 +1,893,929 | +24% | +$18.7M |
|
|
7
Biogen
BIIB
$19.4B
| $96M | 5.47% | 343,200 +108,900 | +46% | +$30.5M |
|
|
RVNC
8
DELISTED
Revance Therapeutics, Inc.
RVNC
| $89.5M | 5.1% | 3,201,866 +528,553 | +20% | +$14.8M |
|
|
9
eHealth
EHTH
$118M
| $77M | 4.39% | 1,058,370 +471,371 | +80% | +$34.3M |
|
10
Acadia Pharmaceuticals
ACAD
$4.38B
| $60.3M | 3.44% | 2,337,877 +36,400 | +2% | +$939K |
|
|
EPZM
11
DELISTED
Epizyme, Inc
EPZM
| $59.7M | 3.4% | 6,856,513 +117,600 | +2% | +$1.02M |
|
|
12
Vanda Pharmaceuticals
VNDA
$279M
| $57M | 3.25% | 3,791,805 -438,743 | -10% | -$6.59M |
|
13
Karyopharm Therapeutics
KPTI
$61.7M
| $56.4M | 3.22% | 5,363,652 +96,000 | +2% | +$1.01M |
|
|
SAGE
14
DELISTED
Sage Therapeutics
SAGE
| $44.9M | 2.56% | 600,500 +10,300 | +2% | +$771K |
|
15
Prothena Corp
PRTA
$441M
| $43.8M | 2.49% | 1,742,505 +50,700 | +3% | +$1.27M |
|
|
ALXN
16
DELISTED
Alexion Pharmaceuticals Inc
ALXN
| $36M | 2.05% | 235,276 -268,153 | -53% | -$41M |
|
|
CLVS
17
DELISTED
Clovis Oncology, Inc.
CLVS
| $31.5M | 1.79% | 4,484,411 +15,000 | +0.3% | +$105K |
|
18
Align Technology
ALGN
$10.3B
| $30M | 1.71% | 55,405 -12,100 | -18% | -$6.55M |
|
|
GRTS
19
DELISTED
Gritstone bio, Inc. Common Stock
GRTS
| $21.7M | 1.23% | +2,298,382 | New | +$21.7M |
|
20
Gossamer Bio
GOSS
$562M
| $16.4M | 0.93% | 1,772,950 +33,900 | +2% | +$314K |
|
21
Puma Biotechnology
PBYI
$254M
| $13.5M | 0.77% | 1,392,997 +19,100 | +1% | +$186K |
|
22
AnaptysBio
ANAB
$569M
| $9.41M | 0.54% | 436,592 +20,300 | +5% | +$437K |
|
23
Alkermes
ALKS
$4.78B
| $9.1M | 0.52% | 487,100 +336,502 | +223% | +$6.29M |
|
|
DRNA
24
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
| $8.51M | 0.48% | 332,713 +900 | +0.3% | +$23K |
|
|
KLDO
25
DELISTED
Kaleido Biosciences, Inc. Common Stock
KLDO
| $6.37M | 0.36% | 786,400 | – | – |
|