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PAI

Palo Alto Investors Portfolio holdings

AUM $654M
1-Year Est. Return 77.8%
This Fund
S&P 500
This Quarter Est. Return
+25.06%
1 Year Est. Return
+77.8%
3 Year Est. Return
+127.05%
5 Year Est. Return
+199.24%
10 Year Est. Return
+2,229.57%
AUM
$1.21B
AUM Growth
+$138M
Cap. Flow
-$5.83M
Cap. Flow %
-0.48%
Top 10 Hldgs %
71.65%
Holding
41
New
7
Increased
11
Reduced
13
Closed
2
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
ITMN
1
DELISTED
INTERMUNE INC
ITMN
$148M 12.22%
4,418,662
+599,056
+16% +$13.3M
AUXL
2
DELISTED
AUXILIUM PHARAMCEUTICALS INC
AUXL
$132M 10.88%
4,842,031
-41,848
-0.9% -$1.11M
CYBX
3
DELISTED
CYBERONICS INC
CYBX
$112M 9.23%
1,711,730
-239,851
-12% -$16.1M
UTHR icon
4
United Therapeutics
UTHR
$23.1B
$104M 8.56%
1,101,028
+5,600
+0.5% +$573K
CBST
5
DELISTED
CUBIST PHARMACEUTICALS INC
CBST
$100M 8.28%
1,369,211
+33,075
+2% +$2.47M
QCOR
6
DELISTED
QUESTCOR PHARMA INC
QCOR
$62.9M 5.2%
969,495
+5,500
+0.6% +$351K
ABMD
7
DELISTED
Abiomed Inc
ABMD
$57.3M 4.74%
2,202,289
-485,058
-18% -$13.4M
VNDA icon
8
Vanda Pharmaceuticals
VNDA
$302M
$52.3M 4.32%
3,215,424
-23,200
-0.7% -$330K
BMRN icon
9
BioMarin Pharmaceuticals
BMRN
$12.4B
$50.9M 4.2%
745,687
+4,600
+0.6% +$339K
STAA icon
10
STAAR Surgical
STAA
$1.21B
$48.8M 4.03%
2,593,653
-620,600
-19% -$10M
KYTH
11
DELISTED
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
$36M 2.97%
905,259
+4,700
+0.5% +$210K
ANAC
12
DELISTED
ANACOR PHARMACEUTICALS INC COM
ANAC
$31.5M 2.6%
1,572,078
-31,200
-2% -$605K
AMAG
13
DELISTED
AMAG Pharmaceuticals
AMAG
$31.2M 2.58%
1,614,536
-146,796
-8% -$3.12M
ALIM
14
DELISTED
Alimera Sciences
ALIM
$28.7M 2.37%
242,332
ARIA
15
DELISTED
Ariad Pharmaceuticals Inc
ARIA
$27.9M 2.3%
3,458,624
+17,300
+0.5% +$135K
SQNM
16
DELISTED
SEQUENOM INC NEW
SQNM
$24M 1.98%
9,788,442
+393,815
+4% +$939K
PRTA icon
17
Prothena Corp
PRTA
$450M
$20.4M 1.69%
532,918
-4,500
-0.8% -$145K
RIGL icon
18
Rigel Pharmaceuticals
RIGL
$750M
$20.1M 1.66%
516,930
-4,770
-0.9% -$170K
EIGR
19
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$17.8M 1.47%
+3,314
New +$15.7M
MNTA
20
DELISTED
Momenta Pharmaceuticals, Inc.
MNTA
$15.3M 1.27%
1,314,976
+157,700
+14% +$2.67M
NPSP
21
DELISTED
NPS PHARMACEUTICALS INC
NPSP
$13M 1.08%
435,200
-3,900
-0.9% -$134K
CLVS
22
DELISTED
Clovis Oncology, Inc.
CLVS
$12.9M 1.07%
186,900
QLTI
23
DELISTED
QLT Inc
QLTI
$11.3M 0.94%
2,041,043
-12,268
-0.6% -$76K
EXAS
24
DELISTED
Exact Sciences
EXAS
$11M 0.91%
777,676
-8,100
-1% -$109K
OREX
25
DELISTED
Orexigen Therapeutics, Inc.
OREX
$10.8M 0.9%
+166,902
New +$11.3M

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Palo Alto Investors's Q1 2014 Portfolio in Review

As of Q1 2014, Palo Alto Investors held 41 positions worth $1.21B, up 13% from $1.07B the previous quarter. Its ten largest holdings account for 72% of the portfolio.

Palo Alto Investors's Q1 2014 filing shows 7 new, 11 increased, 13 reduced and 2 closed positions. Its largest new stake was Eiger BioPharmaceuticals, Inc.: 3,314 shares worth $17.8M. The largest sale was CYBERONICS INC, an estimated $16.1M.

By sector, the portfolio is most concentrated in Healthcare at 42% of assets, down from 44% a quarter earlier.

  • Palo Alto Investors's largest Q1 2014 buy was Eiger BioPharmaceuticals, Inc.: 3,314 shares worth $17.8M.
  • Palo Alto Investors added most to INTERMUNE INC in Q1 2014, an estimated $13.3M increase.
  • Palo Alto Investors's biggest Q1 2014 reduction was CYBERONICS INC, cutting an estimated $16.1M.
  • Palo Alto Investors fully exited VIROPHARMA INC in Q1 2014, selling an estimated $14.5M.
  • Palo Alto Investors's ten largest holdings make up 72% of its $1.21B portfolio in Q1 2014.
  • Palo Alto Investors opened 7 new positions and closed 2 in Q1 2014.
  • Palo Alto Investors's portfolio value rose 13% quarter-over-quarter to $1.21B.

Based on Palo Alto Investors's 13F filing for Q1 2014, filed 15 May 2014.