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PAI

Palo Alto Investors Portfolio holdings

AUM $654M
1-Year Est. Return 77.8%
This Fund
S&P 500
This Quarter Est. Return
+21.7%
1 Year Est. Return
+77.8%
3 Year Est. Return
+127.05%
5 Year Est. Return
+199.24%
10 Year Est. Return
+2,229.57%
AUM
$1.7B
AUM Growth
+$365M
Cap. Flow
+$98.8M
Cap. Flow %
5.8%
Top 10 Hldgs %
66.83%
Holding
48
New
5
Increased
24
Reduced
10
Closed
2
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
UTHR icon
1
United Therapeutics
UTHR
$23.1B
$182M 10.67%
1,403,128
+104,300
+8% +$13.4M
AUXL
2
DELISTED
AUXILIUM PHARAMCEUTICALS INC
AUXL
$169M 9.92%
4,915,931
+61,300
+1% +$2M
CBST
3
DELISTED
CUBIST PHARMACEUTICALS INC
CBST
$131M 7.7%
1,303,668
-540,020
-29% -$42M
CLVS
4
DELISTED
Clovis Oncology, Inc.
CLVS
$118M 6.91%
2,102,857
+381,100
+22% +$20M
BMRN icon
5
BioMarin Pharmaceuticals
BMRN
$12.4B
$118M 6.91%
1,302,197
+37,800
+3% +$3.14M
ABMD
6
DELISTED
Abiomed Inc
ABMD
$93.6M 5.5%
2,460,124
+30,600
+1% +$965K
CYBX
7
DELISTED
CYBERONICS INC
CYBX
$89.5M 5.26%
1,608,101
-13,000
-0.8% -$680K
AMAG
8
DELISTED
AMAG Pharmaceuticals
AMAG
$85M 4.99%
1,994,200
+379,664
+24% +$13.7M
ANAC
9
DELISTED
ANACOR PHARMACEUTICALS INC COM
ANAC
$81.3M 4.77%
2,521,822
+405,157
+19% +$12.2M
INSM icon
10
Insmed
INSM
$28.6B
$71.6M 4.2%
4,625,648
+733,449
+19% +$10.4M
WMGI
11
DELISTED
Wright Medical Group Inc
WMGI
$54.8M 3.22%
2,039,751
+1,207,022
+145% +$35.3M
VNDA icon
12
Vanda Pharmaceuticals
VNDA
$302M
$54.2M 3.18%
3,786,908
+503,784
+15% +$5.96M
NPSP
13
DELISTED
NPS PHARMACEUTICALS INC
NPSP
$42.6M 2.5%
1,190,263
-509,299
-30% -$15.2M
KYTH
14
DELISTED
KYTHERA BIOPHARMACEUTICALS, INC COM
KYTH
$38.9M 2.28%
1,121,884
+19,703
+2% +$688K
SQNM
15
DELISTED
SEQUENOM INC NEW
SQNM
$36.7M 2.16%
9,925,742
+115,300
+1% +$374K
EIGR
16
DELISTED
Eiger BioPharmaceuticals, Inc.
EIGR
$27.4M 1.61%
3,120
-118
-4% -$685K
CELG
17
DELISTED
Celgene Corp
CELG
$24.1M 1.42%
215,500
+43,900
+26% +$4.63M
STAA icon
18
STAAR Surgical
STAA
$1.21B
$24M 1.41%
2,629,622
+30,069
+1% +$291K
GILD icon
19
Gilead Sciences
GILD
$165B
$22.1M 1.3%
234,600
+67,100
+40% +$6.94M
SHPG
20
DELISTED
Shire pic
SHPG
$18.2M 1.07%
85,600
+21,900
+34% +$4.65M
MNTA
21
DELISTED
Momenta Pharmaceuticals, Inc.
MNTA
$17.5M 1.03%
1,455,176
ALIM
22
DELISTED
Alimera Sciences
ALIM
$16.7M 0.98%
200,920
-1,764
-0.9% -$143K
FOLD
23
DELISTED
Amicus Therapeutics
FOLD
$16.3M 0.96%
1,956,376
MDVN
24
DELISTED
MEDIVATION, INC.
MDVN
$16.1M 0.94%
322,600
+62,400
+24% +$3.24M
ARIA
25
DELISTED
Ariad Pharmaceuticals Inc
ARIA
$15.3M 0.9%
2,231,717

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Palo Alto Investors's Q4 2014 Portfolio in Review

As of Q4 2014, Palo Alto Investors held 48 positions worth $1.7B, up 27% from $1.34B the previous quarter. Its ten largest holdings account for 67% of the portfolio.

Palo Alto Investors deployed $98.8M of net new capital in Q4 2014, opening 5 new positions and adding to 24 existing holdings. Its largest new stake was SALIX PHARMACEUTICALS LTD DEL: 76,700 shares worth $8.82M.

By sector, the portfolio is most concentrated in Healthcare at 58% of assets, up from 56% a quarter earlier.

On the sell side, the largest reduction was CUBIST PHARMACEUTICALS INC, an estimated $42M trimmed.

  • Palo Alto Investors's largest Q4 2014 buy was SALIX PHARMACEUTICALS LTD DEL: 76,700 shares worth $8.82M.
  • Palo Alto Investors added most to Wright Medical Group Inc in Q4 2014, an estimated $35.3M increase.
  • Palo Alto Investors's biggest Q4 2014 reduction was CUBIST PHARMACEUTICALS INC, cutting an estimated $42M.
  • Palo Alto Investors fully exited Geron in Q4 2014, selling an estimated $2.32M.
  • Palo Alto Investors's ten largest holdings make up 67% of its $1.7B portfolio in Q4 2014.
  • Palo Alto Investors opened 5 new positions and closed 2 in Q4 2014.
  • Palo Alto Investors's portfolio value rose 27% quarter-over-quarter to $1.7B.

Based on Palo Alto Investors's 13F filing for Q4 2014, filed 17 Feb 2015.