PAI
Palo Alto Investors Portfolio holdings
AUM
$470M
This Quarter Return
+28.06%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$1.82B
AUM Growth
+$1.82B
(+9.4%)
Cap. Flow
-$61.4M
Cap. Flow
% of AUM
-3.37%
Top 10 Holdings %
Top 10 Hldgs %
79.73%
Holding
45
New
4
Increased
25
Reduced
6
Closed
2
Top Buys
| 1 |
BioMarin Pharmaceuticals
BMRN
|
$24.8M |
| 2 |
eHealth
EHTH
|
$22.2M |
| 3 |
Karyopharm Therapeutics
KPTI
|
$12.7M |
| 4 |
Acadia Pharmaceuticals
ACAD
|
$11M |
| 5 |
Gossamer Bio
GOSS
|
$10.8M |
Top Sells
| 1 |
AIMT
Aimmune Therapeutics, Inc.
AIMT
|
$114M |
| 2 |
MNTA
Momenta Pharmaceuticals, Inc.
MNTA
|
$49.2M |
| 3 |
IMMU
Immunomedics Inc
IMMU
|
$28.1M |
| 4 |
Rigel Pharmaceuticals
RIGL
|
$5.66M |
| 5 |
STAAR Surgical
STAA
|
$1.67M |
Sector Composition
| 1 | Healthcare | 74.2% |
| 2 | Financials | 1.22% |
| Name | Market Value | Portfolio Weight | Shares or Principal |
Shares Change % | Capital Flow | |
|---|---|---|---|---|---|---|
|
IMMU
1
DELISTED
Immunomedics Inc
IMMU
| $413M | 22.65% | 4,852,383 -330,600 | -6% | -$28.1M |
|
2
Insmed
INSM
$28.8B
| $194M | 10.64% | 6,032,956 +30,667 | +0.5% | +$986K |
|
|
3
STAAR Surgical
STAA
$1.36B
| $158M | 8.67% | 2,791,693 -29,461 | -1% | -$1.67M |
|
|
ABMD
4
DELISTED
Abiomed Inc
ABMD
| $140M | 7.67% | 504,033 +11,700 | +2% | +$3.24M |
|
|
5
BioMarin Pharmaceuticals
BMRN
$11.2B
| $132M | 7.23% | 1,732,550 +326,600 | +23% | +$24.8M |
|
6
Amicus Therapeutics
FOLD
$2.34B
| $111M | 6.1% | 7,867,114 +532,400 | +7% | +$7.52M |
|
7
United Therapeutics
UTHR
$13.8B
| $79.3M | 4.35% | 785,406 +19,000 | +2% | +$1.92M |
|
|
EPZM
8
DELISTED
Epizyme, Inc
EPZM
| $76.4M | 4.19% | 6,403,600 +889,924 | +16% | +$10.6M |
|
|
9
Acadia Pharmaceuticals
ACAD
$4.38B
| $75.6M | 4.15% | 1,832,300 +267,400 | +17% | +$11M |
|
|
10
Karyopharm Therapeutics
KPTI
$61.7M
| $74.3M | 4.08% | 5,086,152 +866,700 | +21% | +$12.7M |
|
|
ALXN
11
DELISTED
Alexion Pharmaceuticals Inc
ALXN
| $52.4M | 2.87% | 457,529 +12,900 | +3% | +$1.48M |
|
|
RVNC
12
DELISTED
Revance Therapeutics, Inc.
RVNC
| $50.2M | 2.75% | 1,994,905 +290,533 | +17% | +$7.3M |
|
13
Vanda Pharmaceuticals
VNDA
$279M
| $40.3M | 2.21% | 4,170,281 +53,733 | +1% | +$519K |
|
|
SAGE
14
DELISTED
Sage Therapeutics
SAGE
| $36.1M | 1.98% | 590,200 +15,000 | +3% | +$917K |
|
|
AMAG
15
DELISTED
AMAG Pharmaceuticals, Inc.
AMAG
| $28.2M | 1.55% | 3,003,875 +44,288 | +1% | +$416K |
|
|
CLVS
16
DELISTED
Clovis Oncology, Inc.
CLVS
| $26.1M | 1.43% | 4,469,411 +108,000 | +2% | +$630K |
|
|
17
eHealth
EHTH
$118M
| $22.2M | 1.22% | +280,438 | New | +$22.2M |
|
18
Align Technology
ALGN
$10.3B
| $22.1M | 1.21% | 67,505 | – | – |
|
19
Puma Biotechnology
PBYI
$254M
| $13.8M | 0.76% | 1,368,317 +24,420 | +2% | +$246K |
|
|
20
Gossamer Bio
GOSS
$562M
| $13.4M | 0.73% | 1,077,200 +872,986 | +427% | +$10.8M |
|
21
Prothena Corp
PRTA
$441M
| $13.3M | 0.73% | 1,328,734 +557,669 | +72% | +$5.57M |
|
|
KLDO
22
DELISTED
Kaleido Biosciences, Inc. Common Stock
KLDO
| $8.71M | 0.48% | 786,400 | – | – |
|
|
DRNA
23
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
| $5.97M | 0.33% | 331,813 | – | – |
|
24
AnaptysBio
ANAB
$569M
| $5.44M | 0.3% | +368,722 | New | +$5.44M |
|
|
ATNX
25
DELISTED
Athenex, Inc. Common Stock
ATNX
| $3.11M | 0.17% | 256,800 +71,600 | +39% | +$866K |
|