Palo Alto Investors’s Sophiris Bio, Inc. SPHS Stock Holding History

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Shares Change %	Capital Flow	Portfolio Weight	Portfolio Position
2020 Q1	–	Sell	-247,000	Closed	-$91K	–	40
2019 Q4	$91K	Hold	247,000	–	–	0.01%	36
2019 Q3	$144K	Hold	247,000	–	–	0.01%	36
2019 Q2	$209K	Hold	247,000	–	–	0.01%	35
2019 Q1	$245K	Hold	247,000	–	–	0.01%	34
2018 Q4	$205K	Hold	247,000	–	–	0.01%	34
2018 Q3	$689K	Hold	247,000	–	–	0.03%	33
2018 Q2	$694K	Hold	247,000	–	–	0.03%	34
2018 Q1	$496K	Hold	247,000	–	–	0.02%	35
2017 Q4	$561K	Hold	247,000	–	–	0.02%	36
2017 Q3	$530K	Hold	247,000	–	–	0.02%	38
2017 Q2	$543K	Hold	247,000	–	–	0.03%	34
2017 Q1	$699K	Hold	247,000	–	–	0.03%	35
2016 Q4	$692K	Hold	247,000	–	–	0.04%	34
2016 Q3	$768K	Sell	247,000 -247,000	-50%	-$768K	0.04%	37
2016 Q2	$1.06M	Hold	494,000	–	–	0.08%	39
2016 Q1	$711K	Hold	494,000	–	–	0.06%	41
2015 Q4	$879K	Buy	494,000 +302,400	+158%	+$538K	0.05%	40
2015 Q3	$163K	Hold	191,600	–	–	0.01%	47
2015 Q2	$150K	Hold	191,600	–	–	0.01%	45
2015 Q1	$111K	Hold	191,600	–	–	0.01%	46
2014 Q4	$103K	Sell	191,600 -101,300	-35%	-$54.5K	0.01%	46
2014 Q3	$858K	Hold	292,900	–	–	0.06%	41
2014 Q2	$656K	Hold	292,900	–	–	0.05%	40
2014 Q1	$975K	Hold	292,900	–	–	0.08%	35
2013 Q4	$1.08M	Buy	292,900 +237,900	+433%	+$880K	0.1%	32
2013 Q3	$257K	Buy	+55,000	New	+$257K	0.03%	33