PAI

Palo Alto Investors Portfolio holdings

AUM $470M
1-Year Return 2.57%
This Quarter Return
+15.71%
1 Year Return
+2.57%
3 Year Return
+93.77%
5 Year Return
+190.64%
10 Year Return
+955.02%
AUM
$2.12B
AUM Growth
+$363M
Cap. Flow
+$173M
Cap. Flow %
8.18%
Top 10 Hldgs %
72.29%
Holding
40
New
2
Increased
23
Reduced
1
Closed
1

Top Buys

1
ALXN
Alexion Pharmaceuticals Inc
ALXN
+$38M
2
BMRN icon
BioMarin Pharmaceuticals
BMRN
+$37.1M
3
EPZM
Epizyme, Inc
EPZM
+$30.1M
4
ALGN icon
Align Technology
ALGN
+$21.2M
5
ZLTQ
ZELTIQ Aesthetics, Inc.
ZLTQ
+$17.3M

Top Sells

1
ARIA
Ariad Pharmaceuticals Inc
ARIA
+$33.4M
2
PGEN icon
Precigen
PGEN
+$7.47K

Sector Composition

1 Healthcare 95.15%
Name Market Value Portfolio Weight Shares or Principal Shares
Change % 		Capital Flow
VIRX
26
DELISTED
Viracta Therapeutics, Inc. Common Stock
VIRX
$4.77M 0.23%
33,214
– –
ALIM
27
DELISTED
Alimera Sciences, Inc.
ALIM
$4.22M 0.2%
200,920
– –
TLPH icon
28
Talphera
TLPH
$19.3M
$3.25M 0.15%
51,636
– –
DRNA
29
DELISTED
Dicerna Pharmaceuticals, Inc.
DRNA
$1.64M 0.08%
481,519
+323,240
+204% +$1.1M
CYTK icon
30
Cytokinetics
CYTK
$5.69B
$1.59M 0.08%
123,686
– –
ACGN
31
DELISTED
Aceragen, Inc. Common Stock
ACGN
$1.52M 0.07%
4,537
– –
CEMP
32
DELISTED
Cempra, Inc.
CEMP
$1.28M 0.06%
340,320
– –
TRVN
33
DELISTED
Trevena, Inc.
TRVN
$1.25M 0.06%
+546
New +$1.25M
PGEN icon
34
Precigen
PGEN
$1.14B
$830K 0.04%
41,900
-377
-0.9% -$7.47K
SPHS
35
DELISTED
Sophiris Bio, Inc.
SPHS
$699K 0.03%
247,000
– –
OCGN icon
36
Ocugen
OCGN
$412M
$524K 0.02%
5,049
– –
ZGNX
37
DELISTED
Zogenix, Inc.
ZGNX
$320K 0.02%
29,500
– –
ARCT icon
38
Arcturus Therapeutics
ARCT
$490M
$311K 0.01%
38,970
– –
SLNO icon
39
Soleno Therapeutics
SLNO
$2.71B
$301K 0.01%
+5,650
New +$301K
ARIA
40
DELISTED
Ariad Pharmaceuticals Inc
ARIA
– –
-2,682,017
Closed -$33.4M
1
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