Jane Street’s Blueprint Medicines BPMC Stock Holding History
Bought
Maintained
Sold
| Quarter | Market Value | Status | Shares |
Change in Stake | Trade Value | Portfolio Weight | Portfolio Position | |
|---|---|---|---|---|---|---|---|---|
|
2025
Q3 | – | Sell |
-214,394
| Closed | -$27.5M | – | 10812 |
|
|
2025
Q2 | $27.5M | Sell |
214,394
-161,424
| -43% | -$16.8M | 0.01% | 1161 |
|
|
2025
Q1 | $33.3M | Sell |
375,818
-32,404
| -8% | -$3.16M | 0.01% | 927 |
|
|
2024
Q4 | $35.6M | Buy |
408,222
+219,085
| +116% | +$20.1M | 0.01% | 876 |
|
|
2024
Q3 | $17.5M | Buy |
189,137
+46,780
| +33% | +$4.65M | ﹤0.01% | 1350 |
|
|
2024
Q2 | $15.3M | Sell |
142,357
-25,349
| -15% | -$2.54M | ﹤0.01% | 1554 |
|
|
2024
Q1 | $15.9M | Buy |
167,706
+67,334
| +67% | +$5.77M | ﹤0.01% | 1378 |
|
|
2023
Q4 | $9.26M | Buy |
100,372
+83,273
| +487% | +$5.4M | ﹤0.01% | 2047 |
|
|
2023
Q3 | $859K | Sell |
17,099
-57,243
| -77% | -$3.06M | ﹤0.01% | 5425 |
|
|
2023
Q2 | $4.7M | Buy |
74,342
+9,702
| +15% | +$527K | ﹤0.01% | 2832 |
|
|
2023
Q1 | $2.91M | Sell |
64,640
-8,213
| -11% | -$370K | ﹤0.01% | 3196 |
|
|
2022
Q4 | $3.19M | Buy |
72,853
+49,852
| +217% | +$2.39M | ﹤0.01% | 3127 |
|
|
2022
Q3 | $1.52M | Sell |
23,001
-8,229
| -26% | -$529K | ﹤0.01% | 4667 |
|
|
2022
Q2 | $1.58M | Buy |
31,230
+27,613
| +763% | +$1.62M | ﹤0.01% | 4613 |
|
|
2022
Q1 | $231K | Sell |
3,617
-3,340
| -48% | -$240K | ﹤0.01% | 8811 |
|
|
2021
Q4 | $745K | Sell |
6,957
-27,270
| -80% | -$2.85M | ﹤0.01% | 6505 |
|
|
2021
Q3 | $3.52M | Buy |
34,227
+19,049
| +126% | +$1.77M | ﹤0.01% | 3357 |
|
|
2021
Q2 | $1.34M | Buy |
+15,178
| New | +$1.39M | ﹤0.01% | 5189 |
|
|
2021
Q1 | – | Sell |
-20,747
| Closed | -$2.07M | – | 9094 |
|
|
2020
Q4 | $2.33M | Sell |
20,747
-8,168
| -28% | -$861K | ﹤0.01% | 3229 |
|
|
2020
Q3 | $2.68M | Buy |
28,915
+22,426
| +346% | +$1.73M | ﹤0.01% | 2594 |
|
|
2020
Q2 | $506K | Sell |
6,489
-3,501
| -35% | -$237K | ﹤0.01% | 5069 |
|
|
2020
Q1 | $584K | Sell |
9,990
-66,570
| -87% | -$4.28M | ﹤0.01% | 3453 |
|
|
2019
Q4 | $6.13M | Buy |
76,560
+45,133
| +144% | +$3.38M | 0.01% | 927 |
|
|
2019
Q3 | $2.31M | Sell |
31,427
-993
| -3% | -$85.8K | ﹤0.01% | 1653 |
|
|
2019
Q2 | $3.06M | Buy |
32,420
+19,542
| +152% | +$1.61M | 0.01% | 1461 |
|
|
2019
Q1 | $1.03M | Buy |
+12,878
| New | +$952K | ﹤0.01% | 2762 |
|
|
2018
Q3 | – | Sell |
-3,246
| Closed | -$206K | – | 5089 |
|
|
2018
Q2 | $206K | Buy |
+3,246
| New | +$258K | ﹤0.01% | 4531 |
|
|
2017
Q4 | – | Sell |
-17,204
| Closed | -$1.2M | – | 4573 |
|
|
2017
Q3 | $1.2M | Buy |
+17,204
| New | +$919K | ﹤0.01% | 2106 |
|
|
2017
Q2 | – | Sell |
-12,635
| Closed | -$505K | – | 4329 |
|
|
2017
Q1 | $505K | Buy |
+12,635
| New | +$452K | ﹤0.01% | 2861 |
|
Other funds holding BPMC
IA
HNB
Jane Street's BPMC Position: Q3 2025 in Review
Jane Street sold out of Blueprint Medicines (BPMC) in Q3 2025, closing a stake of 214,394 shares — an estimated $27.5M sold.
Jane Street first reported a position in BPMC in Q1 2017 and held it in 28 quarters. The position peaked at $35.6M in Q4 2024. 5 funds tracked by Wall St. Rank hold BPMC as of Q3 2025.
- Jane Street reported no remaining Blueprint Medicines position as of Q3 2025 after selling out during the quarter.
- Jane Street sold 214,394 Blueprint Medicines shares in Q3 2025, an estimated $27.5M.
- Jane Street first reported a position in Blueprint Medicines in Q1 2017 and held it in 28 quarters.
- Jane Street's Blueprint Medicines position peaked at $35.6M in Q4 2024.
- 5 funds tracked by Wall St. Rank held Blueprint Medicines as of Q3 2025.
Based on Jane Street's 13F filing for Q3 2025, filed 14 Nov 2025.