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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

248 hedge funds and large institutions have $3.74B invested in Blueprint Medicines in 2022 Q1 according to their latest regulatory filings, with 34 funds opening new positions, 85 increasing their positions, 91 reducing their positions, and 64 closing their positions.

New
Increased
Maintained
Reduced
Closed

59% more call options, than puts

Call options by funds: $11.6M | Put options by funds: $7.29M

0.66% more ownership

Funds ownership: 100.38%101.04% (+0.66%)

7% less repeat investments, than reductions

Existing positions increased: 85 | Existing positions reduced: 91

11% less funds holding

Funds holding: 280248 (-32)

17% less funds holding in top 10

Funds holding in top 10: 65 (-1)

41% less capital invested

Capital invested by funds: $6.29B → $3.74B (-$2.55B)

47% less first-time investments, than exits

New positions opened: 34 | Existing positions closed: 64

Holders
248
Holders Change
-32
Holders Change %
-11.43%
% of All Funds
3.91%
Holding in Top 10
5
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-16.67%
% of All Funds
0.08%
New
34
Increased
85
Reduced
91
Closed
64
Calls
$11.6M
Puts
$7.29M
Net Calls
+$4.33M
Net Calls Change
+$6.7M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$353M -$625K -8,711 -0.2%
BlackRock
2
BlackRock
New York
$344M +$3.32M +46,264 +0.9%
Fidelity Investments
3
Fidelity Investments
Massachusetts
$341M +$214M +2,984,929 +127%
T. Rowe Price Associates
4
T. Rowe Price Associates
Maryland
$315M +$27.5M +382,586 +8%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$250M +$31M +431,619 +12%
State Street
6
State Street
Massachusetts
$145M +$38.4M +535,424 +31%
CCM
7
Cadian Capital Management
New York
$123M +$106M +1,470,690 +326%
JP Morgan Chase
8
JP Morgan Chase
New York
$107M +$2.22M +30,963 +2%
CC
9
Casdin Capital
New York
$99M
AllianceBernstein
10
AllianceBernstein
Tennessee
$96.5M +$735K +10,246 +0.7%
FCM
11
Farallon Capital Management
California
$86.7M +$39.1M +545,240 +67%
Westfield Capital Management
12
Westfield Capital Management
Massachusetts
$75M +$5.36M +74,730 +7%
Alkeon Capital Management
13
Alkeon Capital Management
New York
$73.1M -$9.23M -128,601 -10%
William Blair Investment Management
14
William Blair Investment Management
Illinois
$69.3M -$47.5M -662,205 -38%
Geode Capital Management
15
Geode Capital Management
Massachusetts
$66.2M +$479K +6,677 +0.6%
RSCM
16
Rock Springs Capital Management
Maryland
$60.5M +$6.31M +87,960 +10%
Brown Advisory
17
Brown Advisory
Maryland
$60.4M +$5.02M +70,000 +8%
Norges Bank
18
Norges Bank
Norway
$52.3M +$881K +12,269 +2%
ACM
19
Aquilo Capital Management
California
$49.9M +$9.76M +136,000 +21%
American Century Companies
20
American Century Companies
Missouri
$48.3M -$7.76M -108,056 -12%
PAMS
21
Pictet Asset Management (Switzerland)
Switzerland
$42.6M -$28.7M -399,620 -37%
EAM
22
Eventide Asset Management
Massachusetts
$37.8M +$14.1M +196,700 +50%
Northern Trust
23
Northern Trust
Illinois
$37M -$7.59M -105,722 -15%
Dimensional Fund Advisors
24
Dimensional Fund Advisors
Texas
$35.4M +$7M +97,557 +21%
BC
25
Boxer Capital
California
$32.4M

BPMC Hedge Fund Activity: Q1 2022 in Review

248 of the 6,340 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q1 2022, worth a combined $3.74B — down 41% from $6.29B a quarter earlier.

Sellers outnumbered buyers: 64 funds closed out of BPMC and 34 opened new positions — a net loss of 30 holders — while 91 trimmed existing stakes and 85 added.

The largest buyer was Fidelity Investments, adding an estimated $214M. The largest seller was TimesSquare Capital Management, cutting an estimated $82.1M.

  • 248 institutional investors held Blueprint Medicines (BPMC) as of Q1 2022, down from 280 in Q4 2021.
  • Funds reported $3.74B of Blueprint Medicines stock for Q1 2022, down 41% quarter-over-quarter.
  • 34 funds opened new Blueprint Medicines positions in Q1 2022 and 64 closed out, a net change of -30 holders.
  • The largest Blueprint Medicines buyer in Q1 2022 was Fidelity Investments, an estimated $214M added.
  • The largest Blueprint Medicines seller in Q1 2022 was TimesSquare Capital Management, an estimated $82.1M sold.

Based on aggregated 13F filings for Q1 2022.