William Blair Investment Management
BPMC

William Blair Investment Management’s Blueprint Medicines BPMC Stock Holding History

William Blair Investment Management’s Portfolio BPMC Stock Details BPMC Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q3 		– Sell
-8,574
Closed -$1.1M – 419
2025
Q2 		$1.1M Sell
8,574
-1,421,094
-99% -$148M ﹤0.01% 368
2025
Q1 		$127M Sell
1,429,668
-515,027
-26% -$50.2M 0.36% 78
2024
Q4 		$170M Buy
1,944,695
+269,896
+16% +$24.7M 0.41% 77
2024
Q3 		$155M Buy
1,674,799
+80,883
+5% +$8.03M 0.38% 92
2024
Q2 		$172M Sell
1,593,916
-114,132
-7% -$11.4M 0.45% 70
2024
Q1 		$162M Sell
1,708,048
-19,797
-1% -$1.7M 0.42% 75
2023
Q4 		$159M Buy
1,727,845
+271,216
+19% +$17.6M 0.46% 75
2023
Q3 		$73.2M Sell
1,456,629
-17,861
-1% -$954K 0.24% 115
2023
Q2 		$93.2M Buy
1,474,490
+392,041
+36% +$21.3M 0.3% 100
2023
Q1 		$48.7M Buy
1,082,449
+57,835
+6% +$2.61M 0.17% 127
2022
Q4 		$44.9M Sell
1,024,614
-49,670
-5% -$2.38M 0.17% 125
2022
Q3 		$70.8M Buy
1,074,284
+9,156
+0.9% +$588K 0.28% 104
2022
Q2 		$53.8M Sell
1,065,128
-20,388
-2% -$1.19M 0.2% 125
2022
Q1 		$69.3M Sell
1,085,516
-662,205
-38% -$47.5M 0.21% 132
2021
Q4 		$187M Buy
1,747,721
+30,557
+2% +$3.2M 0.51% 72
2021
Q3 		$177M Buy
1,717,164
+681,246
+66% +$63.4M 0.5% 68
2021
Q2 		$91.1M Sell
1,035,918
-23,353
-2% -$2.14M 0.29% 113
2021
Q1 		$103M Buy
1,059,271
+76,457
+8% +$7.63M 0.33% 101
2020
Q4 		$110M Buy
+982,814
New +$104M 0.37% 98

Other funds holding BPMC

DekaBank Deutsche Girozentrale
DekaBank Deutsche Girozentrale Frankfurt, Germany $59.2B AUM 26.02% 1-Year Est. Return
VanEck Associates
VanEck Associates New York $133B AUM 72.99% 1-Year Est. Return
IA
IFP Advisors Tampa, Florida $5.54B AUM 27.43% 1-Year Est. Return
Osaic Holdings
Osaic Holdings Scottsdale, Arizona $68.3B AUM 20.5% 1-Year Est. Return
HNB
Huntington National Bank Columbus, Ohio $18.1B AUM 24.69% 1-Year Est. Return

William Blair Investment Management's BPMC Position: Q3 2025 in Review

William Blair Investment Management sold out of Blueprint Medicines (BPMC) in Q3 2025, closing a stake of 8,574 shares — an estimated $1.1M sold.

William Blair Investment Management first reported a position in BPMC in Q4 2020 and held it in 19 quarters. The position peaked at $187M in Q4 2021. 5 funds tracked by Wall St. Rank hold BPMC as of Q3 2025.

  • William Blair Investment Management reported no remaining Blueprint Medicines position as of Q3 2025 after selling out during the quarter.
  • William Blair Investment Management sold 8,574 Blueprint Medicines shares in Q3 2025, an estimated $1.1M.
  • William Blair Investment Management first reported a position in Blueprint Medicines in Q4 2020 and held it in 19 quarters.
  • William Blair Investment Management's Blueprint Medicines position peaked at $187M in Q4 2021.
  • 5 funds tracked by Wall St. Rank held Blueprint Medicines as of Q3 2025.

Based on William Blair Investment Management's 13F filing for Q3 2025, filed 12 Nov 2025.