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BPMC

Blueprint Medicines
BPMC

Delisted

BPMC was delisted on the 17th of July, 2025.

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288 hedge funds and large institutions have $6.12B invested in Blueprint Medicines in 2021 Q3 according to their latest regulatory filings, with 40 funds opening new positions, 99 increasing their positions, 94 reducing their positions, and 29 closing their positions.

New
Increased
Maintained
Reduced
Closed

95% more call options, than puts

Call options by funds: $36.7M | Put options by funds: $18.9M

60% more funds holding in top 10

Funds holding in top 10: 5 → 8 (+3)

38% more first-time investments, than exits

New positions opened: 40 | Existing positions closed: 29

19% more capital invested

Capital invested by funds: $5.14B → $6.12B (+$981M)

2% more funds holding

Funds holding: 281 → 288 (+7)

1.59% more ownership

Funds ownership: 100.24% → 101.83% (+1.6%)

5% more repeat investments, than reductions

Existing positions increased: 99 | Existing positions reduced: 94

Holders
288
Holders Change
+7
Holders Change %
+2.49%
% of All Funds
5.04%
Holding in Top 10
8
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+60%
% of All Funds
0.14%
New
40
Increased
99
Reduced
94
Closed
29
Calls
$36.7M
Puts
$18.9M
Net Calls
+$17.8M
Net Calls Change
+$23.6M

Top Buyers

1
Wellington Management Group
Wellington Management Group
Massachusetts
+$110M
2
William Blair Investment Management
William Blair Investment Management
Illinois
+$63.4M
3
BC
Boxer Capital
California
+$39.6M
4
MWNA
Marshall Wace North America
New York
+$36M
5
Fisher Asset Management
Fisher Asset Management
Washington
+$29.4M

Top Sellers

1
Fidelity Investments
Fidelity Investments
Massachusetts
-$96.7M
2
HA
HHLR Advisors
Cayman Islands
-$55.9M
3
Victory Capital Management
Victory Capital Management
Texas
-$48.5M
4
Morgan Stanley
Morgan Stanley
New York
-$37.3M
5
CCM
Cadian Capital Management
New York
-$25.1M
Name Holding Trade Value Shares
Change 		Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$574M +$1.64M +17,589 +0.3%
BlackRock
2
BlackRock
New York
$534M +$1.13M +12,096 +0.2%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$449M +$10.2M +109,714 +3%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$330M -$96.7M -1,038,167 -24%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$329M +$110M +1,182,979 +59%
William Blair Investment Management
6
William Blair Investment Management
Illinois
$177M +$63.4M +681,246 +66%
State Street
7
State Street
Massachusetts
$174M +$3.64M +39,138 +2%
CC
8
Casdin Capital
New York
$159M – – –
JP Morgan Chase
9
JP Morgan Chase
New York
$156M -$4.85M -52,085 -3%
TCM
10
TimesSquare Capital Management
New York
$151M -$9.92M -106,550 -7%
AllianceBernstein
11
AllianceBernstein
Tennessee
$143M -$748K -8,035 -0.6%
Macquarie Group
12
Macquarie Group
Australia
$133M +$12.6M +134,967 +12%
Alkeon Capital Management
13
Alkeon Capital Management
New York
$131M +$18.6M +200,000 +19%
Westfield Capital Management
14
Westfield Capital Management
Massachusetts
$125M +$3.28M +35,234 +3%
CCM
15
Cadian Capital Management
New York
$108M -$25.1M -269,110 -20%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$104M -$852K -9,151 -0.9%
FCM
17
Farallon Capital Management
California
$97.1M -$16.8M -180,597 -16%
PAMS
18
Pictet Asset Management (Switzerland)
Switzerland
$95.7M +$86.7M +931,016 New
American Century Companies
19
American Century Companies
Missouri
$89M +$5.89M +63,302 +8%
RSCM
20
Rock Springs Capital Management
Maryland
$87.4M +$3.8M +40,799 +5%
Brown Advisory
21
Brown Advisory
Maryland
$87.3M +$4.97M +53,317 +7%
APM
22
Avidity Partners Management
Texas
$85.5M +$25M +268,800 +48%
Norges Bank
23
Norges Bank
Norway
$75.8M +$5.98M +64,184 +10%
Northern Trust
24
Northern Trust
Illinois
$72.5M -$967K -10,388 -1%
Bank of New York Mellon
25
Bank of New York Mellon
New York
$70.6M -$788K -8,461 -1%
1
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BPMC Hedge Fund Activity: Q3 2021 in Review

288 of the 5,712 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q3 2021, worth a combined $6.12B — up 19% from $5.14B a quarter earlier.

Buyers outnumbered sellers: 40 funds opened new BPMC positions and 29 closed out — a net gain of 11 holders — while 99 added to existing stakes and 94 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $110M. The largest seller was Fidelity Investments, cutting an estimated $96.7M.

  • 288 institutional investors held Blueprint Medicines (BPMC) as of Q3 2021, up from 281 in Q2 2021.
  • Funds reported $6.12B of Blueprint Medicines stock for Q3 2021, up 19% quarter-over-quarter.
  • 40 funds opened new Blueprint Medicines positions in Q3 2021 and 29 closed out, a net change of +11 holders.
  • The largest Blueprint Medicines buyer in Q3 2021 was Wellington Management Group, an estimated $110M added.
  • The largest Blueprint Medicines seller in Q3 2021 was Fidelity Investments, an estimated $96.7M sold.

Based on aggregated 13F filings for Q3 2021.