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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

281 hedge funds and large institutions have $5.14B invested in Blueprint Medicines in 2021 Q2 according to their latest regulatory filings, with 54 funds opening new positions, 109 increasing their positions, 72 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

54% more first-time investments, than exits

New positions opened: 54 | Existing positions closed: 35

51% more repeat investments, than reductions

Existing positions increased: 109 | Existing positions reduced: 72

7% more funds holding

Funds holding: 263281 (+18)

0.71% less ownership

Funds ownership: 100.96%100.24% (-0.71%)

10% less capital invested

Capital invested by funds: $5.69B → $5.14B (-$550M)

29% less funds holding in top 10

Funds holding in top 10: 75 (-2)

39% less call options, than puts

Call options by funds: $8.99M | Put options by funds: $14.8M

Holders
281
Holders Change
+18
Holders Change %
+6.84%
% of All Funds
4.89%
Holding in Top 10
5
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-28.57%
% of All Funds
0.09%
New
54
Increased
109
Reduced
72
Closed
35
Calls
$8.99M
Puts
$14.8M
Net Calls
-$5.78M
Net Calls Change
+$2.96M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$490M +$4.74M +51,714 +0.9%
BlackRock
2
BlackRock
New York
$456M +$13.3M +145,232 +3%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$375M +$19.5M +212,840 +5%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$374M -$2.15M -23,485 -0.5%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$177M +$62.4M +680,785 +51%
State Street
6
State Street
Massachusetts
$145M +$12.1M +131,741 +9%
TCM
7
TimesSquare Capital Management
New York
$139M +$13.4M +146,025 +10%
JP Morgan Chase
8
JP Morgan Chase
New York
$138M +$2.98M +32,553 +2%
CC
9
Casdin Capital
New York
$136M
AllianceBernstein
10
AllianceBernstein
Tennessee
$123M +$263K +2,870 +0.2%
CCM
11
Cadian Capital Management
New York
$116M +$37.3M +407,611 +45%
Westfield Capital Management
12
Westfield Capital Management
Massachusetts
$104M +$4.73M +51,632 +5%
Macquarie Group
13
Macquarie Group
Australia
$102M +$29.2M +318,833 +38%
FCM
14
Farallon Capital Management
California
$99M +$39.4M +430,209 +62%
Alkeon Capital Management
15
Alkeon Capital Management
New York
$94.3M +$9.16M +100,000 +10%
William Blair Investment Management
16
William Blair Investment Management
Illinois
$91.1M -$2.14M -23,353 -2%
Geode Capital Management
17
Geode Capital Management
Massachusetts
$89.9M +$5.1M +55,705 +6%
RSCM
18
Rock Springs Capital Management
Maryland
$71.1M +$5.69M +62,128 +8%
American Century Companies
19
American Century Companies
Missouri
$70.5M -$2.81M -30,640 -4%
Brown Advisory
20
Brown Advisory
Maryland
$70M +$3.58M +39,049 +5%
PAMU
21
Pictet Asset Management (UK)
United Kingdom
$65.6M +$4.26M +46,461 +7%
Northern Trust
22
Northern Trust
Illinois
$63M +$6.48M +70,700 +11%
Bank of New York Mellon
23
Bank of New York Mellon
New York
$61.2M +$2.2M +23,977 +4%
Norges Bank
24
Norges Bank
Norway
$59.2M -$3.38M -36,935 -5%
HA
25
HHLR Advisors
Cayman Islands
$55.9M -$11.3M -123,389 -16%

BPMC Hedge Fund Activity: Q2 2021 in Review

281 of the 5,745 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q2 2021, worth a combined $5.14B — down 9.7% from $5.69B a quarter earlier.

Buyers outnumbered sellers: 54 funds opened new BPMC positions and 35 closed out — a net gain of 19 holders — while 109 added to existing stakes and 72 trimmed.

The largest buyer was Wellington Management Group, adding an estimated $62.4M. The largest seller was Lone Pine Capital, exiting entirely with an estimated $263M sold.

  • 281 institutional investors held Blueprint Medicines (BPMC) as of Q2 2021, up from 263 in Q1 2021.
  • Funds reported $5.14B of Blueprint Medicines stock for Q2 2021, down 9.7% quarter-over-quarter.
  • 54 funds opened new Blueprint Medicines positions in Q2 2021 and 35 closed out, a net change of +19 holders.
  • The largest Blueprint Medicines buyer in Q2 2021 was Wellington Management Group, an estimated $62.4M added.
  • The largest Blueprint Medicines seller in Q2 2021 was Lone Pine Capital, an estimated $263M sold.

Based on aggregated 13F filings for Q2 2021.