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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

280 hedge funds and large institutions have $6.29B invested in Blueprint Medicines in 2021 Q4 according to their latest regulatory filings, with 30 funds opening new positions, 98 increasing their positions, 108 reducing their positions, and 35 closing their positions.

New
Increased
Maintained
Reduced
Closed

3% more capital invested

Capital invested by funds: $6.12B → $6.29B (+$172M)

9% less repeat investments, than reductions

Existing positions increased: 98 | Existing positions reduced: 108

1.45% less ownership

Funds ownership: 101.83%100.38% (-1.5%)

3% less funds holding

Funds holding: 288280 (-8)

14% less first-time investments, than exits

New positions opened: 30 | Existing positions closed: 35

20% less call options, than puts

Call options by funds: $9.29M | Put options by funds: $11.7M

25% less funds holding in top 10

Funds holding in top 10: 86 (-2)

Holders
280
Holders Change
-8
Holders Change %
-2.78%
% of All Funds
4.31%
Holding in Top 10
6
Holding in Top 10 Change
-2
Holding in Top 10 Change %
-25%
% of All Funds
0.09%
New
30
Increased
98
Reduced
108
Closed
35
Calls
$9.29M
Puts
$11.7M
Net Calls
-$2.37M
Net Calls Change
-$20.2M
Name Holding Trade Value Shares
Change
Change in
Stake
Vanguard Group
1
Vanguard Group
Pennsylvania
$593M -$5.16M -49,361 -0.9%
BlackRock
2
BlackRock
New York
$572M +$14.5M +138,860 +3%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$487M +$18.7M +178,711 +4%
Wellington Management Group
4
Wellington Management Group
Massachusetts
$372M +$29.1M +278,284 +9%
Fidelity Investments
5
Fidelity Investments
Massachusetts
$252M -$90.3M -863,512 -27%
William Blair Investment Management
6
William Blair Investment Management
Illinois
$187M +$3.2M +30,557 +2%
State Street
7
State Street
Massachusetts
$185M +$4.51M +43,086 +3%
JP Morgan Chase
8
JP Morgan Chase
New York
$176M +$13.2M +126,350 +8%
CC
9
Casdin Capital
New York
$166M
AllianceBernstein
10
AllianceBernstein
Tennessee
$161M +$11.1M +106,541 +8%
TCM
11
TimesSquare Capital Management
New York
$149M -$8.5M -81,215 -6%
Macquarie Group
12
Macquarie Group
Australia
$137M -$1.95M -18,656 -1%
Alkeon Capital Management
13
Alkeon Capital Management
New York
$136M
Westfield Capital Management
14
Westfield Capital Management
Massachusetts
$118M -$12.2M -116,662 -10%
PAMS
15
Pictet Asset Management (Switzerland)
Switzerland
$114M +$14.2M +135,596 +15%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$110M +$1.77M +16,881 +2%
APM
17
Avidity Partners Management
Texas
$107M +$17.1M +163,000 +20%
Marshall Wace
18
Marshall Wace
United Kingdom
$102M +$96.6M +923,577 +3,407%
Brown Advisory
19
Brown Advisory
Maryland
$93.9M +$2.83M +27,080 +3%
American Century Companies
20
American Century Companies
Missouri
$92.6M -$46.3K -443 -0.1%
RSCM
21
Rock Springs Capital Management
Maryland
$92.1M +$1.06M +10,096 +1%
FCM
22
Farallon Capital Management
California
$86.9M -$13.9M -132,656 -14%
Norges Bank
23
Norges Bank
Norway
$86.4M +$7.22M +69,031 +9%
Northern Trust
24
Northern Trust
Illinois
$73.4M -$2.08M -19,903 -3%
ACM
25
Aquilo Capital Management
California
$69.1M +$13M +123,866 +24%

BPMC Hedge Fund Activity: Q4 2021 in Review

280 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2021, worth a combined $6.29B — up 2.8% from $6.12B a quarter earlier.

Sellers outnumbered buyers: 35 funds closed out of BPMC and 30 opened new positions — a net loss of 5 holders — while 108 trimmed existing stakes and 98 added.

The largest buyer was Marshall Wace, adding an estimated $96.6M. The largest seller was Fidelity Investments, cutting an estimated $90.3M.

  • 280 institutional investors held Blueprint Medicines (BPMC) as of Q4 2021, down from 288 in Q3 2021.
  • Funds reported $6.29B of Blueprint Medicines stock for Q4 2021, up 2.8% quarter-over-quarter.
  • 30 funds opened new Blueprint Medicines positions in Q4 2021 and 35 closed out, a net change of -5 holders.
  • The largest Blueprint Medicines buyer in Q4 2021 was Marshall Wace, an estimated $96.6M added.
  • The largest Blueprint Medicines seller in Q4 2021 was Fidelity Investments, an estimated $90.3M sold.

Based on aggregated 13F filings for Q4 2021.