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BPMC

Blueprint Medicines

Delisted

BPMC was delisted on the 17th of July, 2025.

259 hedge funds and large institutions have $6.02B invested in Blueprint Medicines in 2023 Q4 according to their latest regulatory filings, with 60 funds opening new positions, 67 increasing their positions, 98 reducing their positions, and 17 closing their positions.

New
Increased
Maintained
Reduced
Closed

253% more first-time investments, than exits

New positions opened: 60 | Existing positions closed: 17

85% more capital invested

Capital invested by funds: $3.25B → $6.02B (+$2.77B)

67% more funds holding in top 10

Funds holding in top 10: 35 (+2)

28% more call options, than puts

Call options by funds: $131M | Put options by funds: $102M

18% more funds holding

Funds holding: 220259 (+39)

0.65% more ownership

Funds ownership: 106.69%107.34% (+0.65%)

32% less repeat investments, than reductions

Existing positions increased: 67 | Existing positions reduced: 98

Holders
259
Holders Change
+39
Holders Change %
+17.73%
% of All Funds
3.78%
Holding in Top 10
5
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+66.67%
% of All Funds
0.07%
New
60
Increased
67
Reduced
98
Closed
17
Calls
$131M
Puts
$102M
Net Calls
+$29M
Net Calls Change
+$56.1M
Name Holding Trade Value Shares
Change
Change in
Stake
BlackRock
1
BlackRock
New York
$607M -$234K -3,608 -0.1%
Vanguard Group
2
Vanguard Group
Pennsylvania
$564M +$9.58M +147,827 +2%
T. Rowe Price Associates
3
T. Rowe Price Associates
Maryland
$501M -$4.38M -67,622 -1%
Fidelity Investments
4
Fidelity Investments
Massachusetts
$401M -$113M -1,736,944 -29%
Wellington Management Group
5
Wellington Management Group
Massachusetts
$394M -$52.1M -804,188 -16%
RSCM
6
Rock Springs Capital Management
Maryland
$266M +$12.7M +196,273 +7%
State Street
7
State Street
Massachusetts
$224M -$13.1M -201,427 -8%
Morgan Stanley
8
Morgan Stanley
New York
$215M +$128M +1,968,917 +537%
Pictet Asset Management
9
Pictet Asset Management
Switzerland
$162M +$64.6M +997,219 +132%
William Blair Investment Management
10
William Blair Investment Management
Illinois
$159M +$17.6M +271,216 +19%
T. Rowe Price Investment Management
11
T. Rowe Price Investment Management
Maryland
$147M -$55.7M -859,380 -35%
Macquarie Group
12
Macquarie Group
Australia
$145M -$706K -10,895 -0.7%
JP Morgan Chase
13
JP Morgan Chase
New York
$140M -$11.3M -174,509 -10%
Lord, Abbett & Co
14
Lord, Abbett & Co
New Jersey
$134M +$93.9M +1,449,414 New
AllianceBernstein
15
AllianceBernstein
Tennessee
$125M -$9.02M -139,271 -9%
Geode Capital Management
16
Geode Capital Management
Massachusetts
$122M +$3.94M +60,759 +5%
PCH
17
Polar Capital Holdings
United Kingdom
$79.8M -$11.3M -175,000 -17%
WP
18
Woodline Partners
California
$75.1M +$13.8M +212,446 +35%
American Century Companies
19
American Century Companies
Missouri
$65.7M +$2.64M +40,762 +6%
Brown Advisory
20
Brown Advisory
Maryland
$62.7M +$2.52M +38,881 +6%
Alkeon Capital Management
21
Alkeon Capital Management
New York
$59.4M -$19.4M -300,000 -32%
APM
22
Avidity Partners Management
Texas
$56.7M -$8.85M -136,600 -18%
Norges Bank
23
Norges Bank
Norway
$55.9M +$1.29M +19,955 +3%
Goldman Sachs
24
Goldman Sachs
New York
$53.3M +$15.1M +233,337 +68%
Northern Trust
25
Northern Trust
Illinois
$52.9M -$969K -14,960 -3%

BPMC Hedge Fund Activity: Q4 2023 in Review

259 of the 6,859 institutional investors tracked by Wall St. Rank reported a position in Blueprint Medicines (BPMC) for Q4 2023, worth a combined $6.02B — up 85% from $3.25B a quarter earlier.

Buyers outnumbered sellers: 60 funds opened new BPMC positions and 17 closed out — a net gain of 43 holders — while 67 added to existing stakes and 98 trimmed.

The largest buyer was Morgan Stanley, adding an estimated $128M. The largest seller was Fidelity Investments, cutting an estimated $113M.

  • 259 institutional investors held Blueprint Medicines (BPMC) as of Q4 2023, up from 220 in Q3 2023.
  • Funds reported $6.02B of Blueprint Medicines stock for Q4 2023, up 85% quarter-over-quarter.
  • 60 funds opened new Blueprint Medicines positions in Q4 2023 and 17 closed out, a net change of +43 holders.
  • The largest Blueprint Medicines buyer in Q4 2023 was Morgan Stanley, an estimated $128M added.
  • The largest Blueprint Medicines seller in Q4 2023 was Fidelity Investments, an estimated $113M sold.

Based on aggregated 13F filings for Q4 2023.