Group One Trading’s Upstream Bio Inc UPB Stock Holding History

Group One Trading’s Portfolio UPB Stock Details UPB Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-1,305	Closed	-$32.5K	–	9385
2025 Q3	$24.5K	Buy	+1,305	New	+$20.3K	﹤0.01%	6541

Other funds holding UPB

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return

Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return

VCM

Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM

YIH

Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return

Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Group One Trading's UPB Position: Q4 2025 in Review

Group One Trading sold out of Upstream Bio Inc (UPB) in Q4 2025, closing a stake of 1,305 shares — an estimated $32.5K sold.

Group One Trading first reported a position in UPB in Q3 2025 and held it in 1 quarter. The position peaked at $24.5K in Q3 2025. 133 funds tracked by Wall St. Rank hold UPB as of Q4 2025.

Group One Trading reported no remaining Upstream Bio Inc position as of Q4 2025 after selling out during the quarter.
Group One Trading sold 1,305 Upstream Bio Inc shares in Q4 2025, an estimated $32.5K.
Group One Trading first reported a position in Upstream Bio Inc in Q3 2025 and held it in 1 quarter.
Group One Trading's Upstream Bio Inc position peaked at $24.5K in Q3 2025.
133 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q4 2025.

Based on Group One Trading's 13F filing for Q4 2025, filed 12 Feb 2026.