Group One Trading
UPB

Group One Trading’s Upstream Bio Inc UPB Stock Holding History

Group One Trading’s Portfolio UPB Stock Details UPB Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$89.1K Buy
9,900
+9,600
+3,200% +$173K ﹤0.01% 4835
2025
Q4 		$8.14K Sell
300
-100
-25% -$2.49K ﹤0.01% 6927
2025
Q3 		$7.52K Buy
+400
New +$6.21K ﹤0.01% 7336

Other funds holding UPB

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
O
OrbiMed New York $5.05B AUM 125.28% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DC
Decheng Capital Menlo Park, California $661M AUM 299.97% 1-Year Est. Return
ES
Enavate Sciences Menlo Park, California $352M AUM 220.14% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
YIH
Y-Intercept (HK) Hong Kong $5.05B AUM 17.89% 1-Year Est. Return
Federated Hermes
Federated Hermes Pittsburgh, Pennsylvania $61.5B AUM 30.7% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Group One Trading's UPB Position: Q4 2025 in Review

Group One Trading sold out of Upstream Bio Inc (UPB) in Q4 2025, closing a stake of 1,305 shares — an estimated $32.5K sold.

Group One Trading first reported a position in UPB in Q3 2025 and held it in 1 quarter. The position peaked at $24.5K in Q3 2025. 133 funds tracked by Wall St. Rank hold UPB as of Q4 2025.

  • Group One Trading reported no remaining Upstream Bio Inc position as of Q4 2025 after selling out during the quarter.
  • Group One Trading sold 1,305 Upstream Bio Inc shares in Q4 2025, an estimated $32.5K.
  • Group One Trading first reported a position in Upstream Bio Inc in Q3 2025 and held it in 1 quarter.
  • Group One Trading's Upstream Bio Inc position peaked at $24.5K in Q3 2025.
  • 133 funds tracked by Wall St. Rank held Upstream Bio Inc as of Q4 2025.

Based on Group One Trading's 13F filing for Q4 2025, filed 12 Feb 2026.