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EcoR1 Capital Portfolio holdings

AUM $2.36B
1-Year Est. Return 204.53%
This Fund
S&P 500
This Quarter Est. Return
-0.77%
1 Year Est. Return
+204.53%
3 Year Est. Return
+306.25%
5 Year Est. Return
+490.45%
10 Year Est. Return
+14,115.48%
AUM
$3.11B
AUM Growth
-$180M
Cap. Flow
-$9.91M
Cap. Flow %
-0.32%
Top 10 Hldgs %
73.57%
Holding
71
New
5
Increased
9
Reduced
9
Closed
13

Top Buys

Rank Stock Value
1
JANX icon
Janux Therapeutics
JANX
+$40.2M
2
RVMD icon
Revolution Medicines
RVMD
+$22M
3
ZYME icon
Zymeworks
ZYME
+$22M
4
LKFT
Lakefront Biotherapeutics American Depositary Shares
LKFT
+$21.1M
5
ARVN icon
Arvinas
ARVN
+$18.8M

Top Sells

Rank Stock Value
1
ZLAB icon
Zai Lab
ZLAB
+$66.2M
2
VTYX
Ventyx Biosciences
VTYX
+$13.1M
3
TSVT
2seventy bio
TSVT
+$10.7M
4
GERN icon
Geron
GERN
+$9.75M
5
AVEO
AVEO Pharmaceuticals, Inc.
AVEO
+$9.72M

Sector Composition

Rank Sector Weight
1 Healthcare 99.82%
2 Financials 0.07%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
NAMSW icon
51
NewAmsterdam Pharma Warrant
NAMSW
$81.7M
$884K 0.03%
66,665
– –
EUCRW
52
DELISTED
Eucrates Biomedical Acquisition Corp. Warrant
EUCRW
$676K 0.02%
66,666
– –
KRON
53
DELISTED
Kronos Bio
KRON
$477K 0.02%
326,780
– –
RNAC icon
54
Cartesian Therapeutics
RNAC
$218M
$278K 0.01%
6,667
-110,000
-94% -$5.17M
CMAXW
55
DELISTED
CareMax, Inc. Warrant
CMAXW
$267K 0.01%
100,000
– –
CYT
56
DELISTED
Cyteir Therapeutics, Inc. Common Stock
CYT
$79.8K ﹤0.01%
+43,823
New +$71.2K
SRZNW icon
57
Surrozen Inc Warrant
SRZNW
$36.6K
$40.1K ﹤0.01%
66,665
– –
ITOS
58
DELISTED
iTeos Therapeutics
ITOS
$17.7K ﹤0.01%
1,300
-39,180
-97% -$702K
ABEO icon
59
Abeona Therapeutics
ABEO
$356M
– –
-1,086,956
Closed -$3.35M
BCAB icon
60
BioAtla
BCAB
$5.34M
– –
-22,489
Closed -$9.28M
DSGN icon
61
Design Therapeutics
DSGN
$751M
– –
-884,903
Closed -$9.08M
DTIL icon
62
Precision BioSciences
DTIL
$178M
– –
-167,866
Closed -$5.99M
GERN icon
63
Geron
GERN
$911M
– –
-4,028,507
Closed -$9.75M
IMTX icon
64
Immatics
IMTX
$1.23B
– –
-743,000
Closed -$6.47M
OBIO icon
65
Orchestra BioMed
OBIO
$228M
– –
-400,000
Closed -$3.99M
PRAX icon
66
Praxis Precision Medicines
PRAX
$8.13B
– –
-105,688
Closed -$3.77M
TSVT
67
DELISTED
2seventy bio
TSVT
– –
-1,143,494
Closed -$10.7M
VTYX
68
DELISTED
Ventyx Biosciences
VTYX
– –
-400,000
Closed -$13.1M
ZLAB icon
69
Zai Lab
ZLAB
$2.07B
– –
-2,157,686
Closed -$66.2M
ARYD
70
DELISTED
ARYA Sciences Acquisition Corp IV Class A Odinary Shares
ARYD
– –
-150,000
Closed -$1.51M
AVEO
71
DELISTED
AVEO Pharmaceuticals, Inc.
AVEO
– –
-650,489
Closed -$9.72M
1 2
3

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EcoR1 Capital's Q1 2023 Portfolio in Review

As of Q1 2023, EcoR1 Capital held 71 positions worth $3.11B, down 5.5% from $3.29B the previous quarter. Its ten largest holdings account for 74% of the portfolio.

EcoR1 Capital's Q1 2023 filing shows 5 new, 9 increased, 9 reduced and 13 closed positions. Its largest new stake was Generation Bio: 195,658 shares worth $8.41M. The largest sale was Zai Lab, an estimated $66.2M.

By sector, the portfolio is most concentrated in Healthcare at 100% of assets, up from 100% a quarter earlier, followed by Financials.

  • EcoR1 Capital's largest Q1 2023 buy was Generation Bio: 195,658 shares worth $8.41M.
  • EcoR1 Capital added most to Janux Therapeutics in Q1 2023, an estimated $40.2M increase.
  • EcoR1 Capital's biggest Q1 2023 reduction was Cullinan Oncology, cutting an estimated $8.69M.
  • EcoR1 Capital fully exited Zai Lab in Q1 2023, selling an estimated $66.2M.
  • EcoR1 Capital's ten largest holdings make up 74% of its $3.11B portfolio in Q1 2023.
  • EcoR1 Capital opened 5 new positions and closed 13 in Q1 2023.
  • EcoR1 Capital's portfolio value fell 5.5% quarter-over-quarter to $3.11B.

Based on EcoR1 Capital's 13F filing for Q1 2023, filed 15 May 2023.