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EcoR1 Capital Portfolio holdings

AUM $2.06B Turnover 46.34%
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+4.73%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$1.11B
AUM Growth
+$59.7M
Cap. Flow
+$37M
Cap. Flow %
3.34%
Top 10 Hldgs %
63.03%
Holding
52
New
19
Increased
6
Reduced
15
Closed
2
Avg Time Held Equity + Options
0.6 years
Top 10 Avg Time Held Equity + Options
1.3 years
Top 20 Avg Time Held Equity + Options
0.8 years
Avg Time Held Equity only
0.6 years
Top 10 Avg Time Held Equity only
1.3 years
Top 20 Avg Time Held Equity only
0.8 years

Top Buys

Rank Stock Value
1
ONCE
Spark Therapeutics, Inc. Common Stock
ONCE
+$57.2M
2
CRSP icon
CRISPR Therapeutics
CRSP
+$26.2M
3
AKCA
Akcea Therapeutics Inc
AKCA
+$22.8M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
+$20.7M
5
RUBY
Rubius Therapeutics, Inc
RUBY
+$13.5M

Top Sells

Rank Stock Value
1
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$55.8M
2
ASND icon
Ascendis Pharma A/S
ASND
+$25.9M
3
IRWD icon
Ironwood Pharmaceuticals
IRWD
+$20.9M
4
SGMO icon
SANGAMO THERAPEUTICS INC
SGMO
+$17.7M
5
WVE icon
Wave Life Sciences
WVE
+$16.6M

Sector Composition

Rank Sector Weight
1 Healthcare 87.05%
2 Miscellaneous 12.95%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow Held Since
DBVT icon
51
DBV Technologies S.A. American Depositary Shares
DBVT
$569M
– –
-29,810
Closed -$5.75M –
MDGL icon
52
Madrigal Pharmaceuticals
MDGL
$10.4B
– –
-199,500
Closed -$55.8M –
1 2
3

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ABTD
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CFA
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DWT
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RMC
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SIC
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FWTB
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EcoR1 Capital's Q3 2018 Portfolio in Review

As of Q3 2018, EcoR1 Capital held 52 positions worth $1.11B, up 5.7% from $1.05B the previous quarter. Its ten largest holdings account for 63% of the portfolio.

EcoR1 Capital deployed $37M of net new capital in Q3 2018, opening 19 new positions and adding to 6 existing holdings. Its largest new stake was Spark Therapeutics, Inc. Common Stock: 837,048 shares worth $45.7M.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, down from 87% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Ascendis Pharma A/S, an estimated $25.9M trimmed.

  • EcoR1 Capital's largest Q3 2018 buy was Spark Therapeutics, Inc. Common Stock: 837,048 shares worth $45.7M.
  • EcoR1 Capital added most to Dicerna Pharmaceuticals, Inc. in Q3 2018, an estimated $12.2M increase.
  • EcoR1 Capital's biggest Q3 2018 reduction was Ascendis Pharma A/S, cutting an estimated $25.9M.
  • EcoR1 Capital fully exited Madrigal Pharmaceuticals in Q3 2018, selling an estimated $55.8M.
  • EcoR1 Capital's ten largest holdings make up 63% of its $1.11B portfolio in Q3 2018.
  • EcoR1 Capital opened 19 new positions and closed 2 in Q3 2018.
  • EcoR1 Capital's portfolio value rose 5.7% quarter-over-quarter to $1.11B.

Based on EcoR1 Capital's 13F filing for Q3 2018, filed 14 Nov 2018.