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EcoR1 Capital Portfolio holdings

AUM $2.06B
1-Year Est. Return 215.32%
This Fund
S&P 500
This Quarter Est. Return
+4.73%
1 Year Est. Return
+215.32%
3 Year Est. Return
+310.3%
5 Year Est. Return
+497.45%
10 Year Est. Return
+14,692.23%
AUM
$1.11B
AUM Growth
+$59.7M
Cap. Flow
+$37M
Cap. Flow %
3.34%
Top 10 Hldgs %
63.03%
Holding
52
New
19
Increased
6
Reduced
15
Closed
2

Top Buys

Rank Stock Value
1
ONCE
Spark Therapeutics, Inc. Common Stock
ONCE
+$57.2M
2
CRSP icon
CRISPR Therapeutics
CRSP
+$26.2M
3
AKCA
Akcea Therapeutics Inc
AKCA
+$22.8M
4
RARE icon
Ultragenyx Pharmaceutical
RARE
+$20.7M
5
RUBY
Rubius Therapeutics, Inc
RUBY
+$13.5M

Top Sells

Rank Stock Value
1
MDGL icon
Madrigal Pharmaceuticals
MDGL
+$55.8M
2
ASND icon
Ascendis Pharma A/S
ASND
+$25.9M
3
IRWD icon
Ironwood Pharmaceuticals
IRWD
+$20.9M
4
SGMO
SANGAMO THERAPEUTICS INC
SGMO
+$17.7M
5
WVE icon
Wave Life Sciences
WVE
+$16.6M

Sector Composition

Rank Sector Weight
1 Healthcare 87.05%
2 Miscellaneous 12.95%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
DBVT
51
DBV Technologies
DBVT
$851M
– –
-29,810
Closed -$5.75M
MDGL icon
52
Madrigal Pharmaceuticals
MDGL
$12.3B
– –
-199,500
Closed -$55.8M
1 2
3

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EcoR1 Capital's Q3 2018 Portfolio in Review

As of Q3 2018, EcoR1 Capital held 52 positions worth $1.11B, up 5.7% from $1.05B the previous quarter. Its ten largest holdings account for 63% of the portfolio.

EcoR1 Capital deployed $37M of net new capital in Q3 2018, opening 19 new positions and adding to 6 existing holdings. Its largest new stake was Spark Therapeutics, Inc. Common Stock: 837,048 shares worth $45.7M.

By sector, the portfolio is most concentrated in Healthcare at 87% of assets, down from 87% a quarter earlier, followed by Miscellaneous.

On the sell side, the largest reduction was Ascendis Pharma A/S, an estimated $25.9M trimmed.

  • EcoR1 Capital's largest Q3 2018 buy was Spark Therapeutics, Inc. Common Stock: 837,048 shares worth $45.7M.
  • EcoR1 Capital added most to Dicerna Pharmaceuticals, Inc. in Q3 2018, an estimated $12.2M increase.
  • EcoR1 Capital's biggest Q3 2018 reduction was Ascendis Pharma A/S, cutting an estimated $25.9M.
  • EcoR1 Capital fully exited Madrigal Pharmaceuticals in Q3 2018, selling an estimated $55.8M.
  • EcoR1 Capital's ten largest holdings make up 63% of its $1.11B portfolio in Q3 2018.
  • EcoR1 Capital opened 19 new positions and closed 2 in Q3 2018.
  • EcoR1 Capital's portfolio value rose 5.7% quarter-over-quarter to $1.11B.

Based on EcoR1 Capital's 13F filing for Q3 2018, filed 14 Nov 2018.