EC
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EcoR1 Capital’s Madrigal Pharmaceuticals MDGL Stock Holding History

EcoR1 Capital’s Portfolio MDGL Stock Details MDGL Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q4 		– Sell
-75,000
Closed -$34.4M – 35
2025
Q3 		$34.4M Hold
75,000
– – 1.65% 15
2025
Q2 		$22.7M Hold
75,000
– – 1.35% 17
2025
Q1 		$24.8M Hold
75,000
– – 1.48% 14
2024
Q4 		$23.1M Hold
75,000
– – 0.92% 24
2024
Q3 		$15.9M Hold
75,000
– – 0.55% 39
2024
Q2 		$21M Hold
75,000
– – 0.64% 34
2024
Q1 		$20M Buy
+75,000
New +$17.7M 0.51% 36
2018
Q3 		– Sell
-199,500
Closed -$55.8M – 53
2018
Q2 		$55.8M Buy
+199,500
New +$35M 6.1% 6
2018
Q1 		– Sell
-35,000
Closed -$3.21M – 33
2017
Q4 		$3.21M Buy
+35,000
New +$2M 0.43% 26

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ACA
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PC
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BlackRock
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Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
State Street
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Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return