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Madrigal Pharmaceuticals

352 hedge funds and large institutions have $10.7B invested in Madrigal Pharmaceuticals in 2025 Q3 according to their latest regulatory filings, with 87 funds opening new positions, 107 increasing their positions, 107 reducing their positions, and 37 closing their positions.

New
Increased
Maintained
Reduced
Closed

135% more first-time investments, than exits

New positions opened: 87 | Existing positions closed: 37

50% more capital invested

Capital invested by funds: $7.13B → $10.7B (+$3.6B)

27% more call options, than puts

Call options by funds: $326M | Put options by funds: $258M

17% more funds holding in top 10

Funds holding in top 10: 1214 (+2)

15% more funds holding

Funds holding: 305352 (+47)

0% more repeat investments, than reductions

Existing positions increased: 107 | Existing positions reduced: 107

0.74% less ownership

Funds ownership: 106.08%105.34% (-0.74%)

Holders
352
Holders Change
+47
Holders Change %
+15.41%
% of All Funds
4.62%
Holding in Top 10
14
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+16.67%
% of All Funds
0.18%
New
87
Increased
107
Reduced
107
Closed
37
Calls
$326M
Puts
$258M
Net Calls
+$68.8M
Net Calls Change
-$69.9M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$982M +$61.8M +165,683 +8%
RI
2
RTW Investments
New York
$914M
PC
3
Paulson & Co
New York
$875M -$67.9M -182,000 -9%
Janus Henderson Group
4
Janus Henderson Group
United Kingdom
$845M -$130M -349,063 -16%
ACA
5
Avoro Capital Advisors
New York
$841M -$15.7M -42,000 -2%
Vanguard Group
6
Vanguard Group
Pennsylvania
$831M -$24.3M -65,227 -3%
BlackRock
7
BlackRock
New York
$715M +$45.1M +120,988 +8%
State Street
8
State Street
Massachusetts
$302M -$12.2M -32,618 -5%
Geode Capital Management
9
Geode Capital Management
Massachusetts
$205M +$11.9M +31,841 +8%
William Blair Investment Management
10
William Blair Investment Management
Illinois
$189M +$22.9M +61,513 +18%
Wellington Management Group
11
Wellington Management Group
Massachusetts
$186M +$148M +397,076 +5,381%
Fidelity Investments
12
Fidelity Investments
Massachusetts
$184M -$16.5M -44,203 -10%
Goldman Sachs
13
Goldman Sachs
New York
$177M +$73.2M +196,260 +103%
T. Rowe Price Associates
14
T. Rowe Price Associates
Maryland
$162M -$58.2M -155,944 -31%
Invesco
15
Invesco
Georgia
$137M +$37M +99,209 +50%
PCH
16
Polar Capital Holdings
United Kingdom
$122M +$14.8M +39,744 +18%
Morgan Stanley
17
Morgan Stanley
New York
$115M +$629K +1,685 +0.7%
Bank of America
18
Bank of America
North Carolina
$112M -$12.3M -32,929 -12%
HRCM
19
Hood River Capital Management
Florida
$111M -$720K -1,930 -0.8%
UBS Group
20
UBS Group
Switzerland
$99.7M -$108M -288,371 -57%
Charles Schwab
21
Charles Schwab
California
$98M +$22.6M +60,567 +40%
Artisan Partners
22
Artisan Partners
Wisconsin
$94.6M +$1.75M +4,683 +2%
EAM
23
Erste Asset Management
Austria
$89.1M
Pictet Asset Management
24
Pictet Asset Management
Switzerland
$87.7M -$6.14M -16,470 -8%
American Century Companies
25
American Century Companies
Missouri
$76M -$809K -2,169 -1%