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Madrigal Pharmaceuticals

378 hedge funds and large institutions have $12.4B invested in Madrigal Pharmaceuticals in 2026 Q1 according to their latest regulatory filings, with 62 funds opening new positions, 130 increasing their positions, 129 reducing their positions, and 63 closing their positions.

New
Increased
Maintained
Reduced
Closed

96% more call options, than puts

Call options by funds: $397M | Put options by funds: $203M

1% more repeat investments, than reductions

Existing positions increased: 130 | Existing positions reduced: 129

0.14% less ownership

Funds ownership: 103.78%103.63% (-0.14%)

2% less first-time investments, than exits

New positions opened: 62 | Existing positions closed: 63

2% less funds holding

Funds holding: 387378 (-9)

9% less capital invested

Capital invested by funds: $13.7B → $12.4B (-$1.28B)

38% less funds holding in top 10

Funds holding in top 10: 138 (-5)

Holders
378
Holders Change
-9
Holders Change %
-2.33%
% of All Funds
4.66%
Holding in Top 10
8
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-38.46%
% of All Funds
0.1%
New
62
Increased
130
Reduced
129
Closed
63
Calls
$397M
Puts
$203M
Net Calls
+$195M
Net Calls Change
+$142M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
1
Baker Bros. Advisors
New York
$1.12B
Janus Henderson Group
2
Janus Henderson Group
United Kingdom
$1.05B +$207M +433,804 +27%
RI
3
RTW Investments
New York
$1.04B
ACA
4
Avoro Capital Advisors
New York
$952M +$5.1M +10,681 +0.6%
BlackRock
5
BlackRock
New York
$817M -$40.5M -84,785 -5%
PC
6
Paulson & Co
New York
$729M -$151M -315,334 -18%
VPM
7
Vanguard Portfolio Management
Pennsylvania
$440M +$402M +841,145 New
VCM
8
Vanguard Capital Management
Pennsylvania
$433M +$395M +827,144 New
Wellington Management Group
9
Wellington Management Group
Massachusetts
$364M +$112M +233,556 +51%
State Street
10
State Street
Massachusetts
$319M +$12.7M +26,522 +5%
Fidelity Investments
11
Fidelity Investments
Massachusetts
$268M +$34.6M +72,330 +16%
Geode Capital Management
12
Geode Capital Management
Massachusetts
$239M +$1.97M +4,127 +0.9%
Citadel Advisors
13
Citadel Advisors
Florida
$238M +$200M +417,709 +1,156%
William Blair Investment Management
14
William Blair Investment Management
Illinois
$178M -$6.55M -13,701 -4%
Invesco
15
Invesco
Georgia
$172M -$17.1M -35,795 -10%
T. Rowe Price Associates
16
T. Rowe Price Associates
Maryland
$172M +$6.9M +14,451 +5%
PCH
17
Polar Capital Holdings
United Kingdom
$151M +$9.15M +19,159 +7%
Goldman Sachs
18
Goldman Sachs
New York
$145M -$13.6M -28,476 -9%
AC
19
Armistice Capital
New York
$139M -$536K -1,122 -0.4%
HRCM
20
Hood River Capital Management
Florida
$131M +$932K +1,951 +0.8%
Lord, Abbett & Co
21
Lord, Abbett & Co
New Jersey
$127M -$989K -2,070 -0.8%
Point72 Asset Management
22
Point72 Asset Management
Connecticut
$118M +$47.3M +99,075 +78%
Charles Schwab
23
Charles Schwab
California
$113M -$1.14M -2,379 -1%
Morgan Stanley
24
Morgan Stanley
New York
$100M +$19.5M +40,832 +27%
Bank of America
25
Bank of America
North Carolina
$99.2M -$108M -226,498 -54%