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Madrigal Pharmaceuticals
MDGL

Overview Fund Activity

318 hedge funds and large institutions have $7.82B invested in Madrigal Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 73 funds opening new positions, 108 increasing their positions, 91 reducing their positions, and 32 closing their positions.

Holders
318
Holders Change
+36
Holders Change %
+12.77%
% of All Funds
4.32%
Holding in Top 10
12
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+20%
% of All Funds
0.16%
New
73
Increased
108
Reduced
91
Closed
32
Calls
$346M
Puts
$164M
Net Calls
+$182M
Net Calls Change
+$149M

Top Buyers

1
Holocene Advisors
1
Holocene Advisors
New York
$129M
2
Adage Capital Partners
2
Adage Capital Partners
Massachusetts
$63.5M
3
Morgan Stanley
3
Morgan Stanley
New York
$127M
4
Susquehanna International Group
4
Susquehanna International Group
Pennsylvania
$47.2M
5
HRCM
5
Hood River Capital Management
Florida
$80.8M

Top Sellers

1
Fidelity Investments
1
Fidelity Investments
Massachusetts
$216M
2
SL
2
Siren LLC
Connecticut
$0
3
Norges Bank
3
Norges Bank
Norway
$0
4
RSCM
4
Rock Springs Capital Management
Maryland
$55.2M
5
Group One Trading
5
Group One Trading
Illinois
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$723M 2,205,849 -2,545 -0.1%
PC
2
Paulson & Co
New York
$695M 2,099,523 +57,523 +3%
ACA
3
Avoro Capital Advisors
New York
$670M 2,022,222 -6,778 -0.3%
RI
4
RTW Investments
New York
$660M 1,993,687 – –
BBA
5
Baker Bros. Advisors
New York
$654M 1,974,590 – –
Vanguard Group
6
Vanguard Group
Pennsylvania
$560M 1,690,111 -16,024 -0.9%
BlackRock
7
BlackRock
New York
$492M 1,486,460 -7,707 -0.5%
State Street
8
State Street
Massachusetts
$251M 758,511 -22,777 -3%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$216M 652,099 -215,751 -25%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$180M 542,633 -46,131 -8%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$139M 420,875 +10,297 +3%
Holocene Advisors
12
Holocene Advisors
New York
$129M 390,545 +390,545 New
Morgan Stanley
13
Morgan Stanley
New York
$127M 384,828 +166,347 +76%
William Blair Investment Management
14
William Blair Investment Management
Illinois
$117M 353,155 -18,616 -5%
UBS Group
15
UBS Group
Switzerland
$106M 321,507 -3,767 -1%
WP
16
Woodline Partners
California
$105M 317,433 +8,316 +3%
Bank of America
17
Bank of America
North Carolina
$81.5M 245,961 +28,133 +13%
HRCM
18
Hood River Capital Management
Florida
$80.8M 243,994 +116,155 +91%
Pictet Asset Management
19
Pictet Asset Management
Switzerland
$68.5M 207,043 -1,441 -0.7%
Adage Capital Partners
20
Adage Capital Partners
Massachusetts
$63.5M 191,609 +171,649 +860%
Goldman Sachs
21
Goldman Sachs
New York
$62.8M 189,639 -41,811 -18%
ACH
22
ArrowMark Colorado Holdings
Colorado
$59.7M 180,109 -19,558 -10%
RSCM
23
Rock Springs Capital Management
Maryland
$55.2M 166,698 -98,514 -37%
EAM
24
Erste Asset Management
Austria
$54.4M 164,400 – –
American Century Companies
25
American Century Companies
Missouri
$52.4M 158,306 +21,457 +16%
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