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Madrigal Pharmaceuticals

321 hedge funds and large institutions have $7.85B invested in Madrigal Pharmaceuticals in 2025 Q1 according to their latest regulatory filings, with 72 funds opening new positions, 109 increasing their positions, 93 reducing their positions, and 32 closing their positions.

New
Increased
Maintained
Reduced
Closed

125% more first-time investments, than exits

New positions opened: 72 | Existing positions closed: 32

111% more call options, than puts

Call options by funds: $346M | Put options by funds: $164M

20% more funds holding in top 10

Funds holding in top 10: 1012 (+2)

17% more repeat investments, than reductions

Existing positions increased: 109 | Existing positions reduced: 93

13% more funds holding

Funds holding: 283321 (+38)

11% more capital invested

Capital invested by funds: $7.08B → $7.85B (+$763M)

2.16% more ownership

Funds ownership: 105.25%107.4% (+2.2%)

Holders
321
Holders Change
+38
Holders Change %
+13.43%
% of All Funds
4.3%
Holding in Top 10
12
Holding in Top 10 Change
+2
Holding in Top 10 Change %
+20%
% of All Funds
0.16%
New
72
Increased
109
Reduced
93
Closed
32
Calls
$346M
Puts
$164M
Net Calls
+$182M
Net Calls Change
+$149M
Name Holding Trade Value Shares
Change
Change in
Stake
Janus Henderson Group
1
Janus Henderson Group
United Kingdom
$723M -$836K -2,545 -0.1%
PC
2
Paulson & Co
New York
$695M +$18.9M +57,523 +3%
ACA
3
Avoro Capital Advisors
New York
$670M -$2.23M -6,778 -0.3%
RI
4
RTW Investments
New York
$660M
BBA
5
Baker Bros. Advisors
New York
$654M
Vanguard Group
6
Vanguard Group
Pennsylvania
$560M -$5.27M -16,024 -0.9%
BlackRock
7
BlackRock
New York
$492M -$2.53M -7,707 -0.5%
State Street
8
State Street
Massachusetts
$251M -$7.48M -22,777 -3%
Fidelity Investments
9
Fidelity Investments
Massachusetts
$216M -$70.9M -215,751 -25%
T. Rowe Price Associates
10
T. Rowe Price Associates
Maryland
$180M -$15.2M -46,131 -8%
Geode Capital Management
11
Geode Capital Management
Massachusetts
$139M +$3.38M +10,297 +3%
Holocene Advisors
12
Holocene Advisors
New York
$129M +$128M +390,545 New
Morgan Stanley
13
Morgan Stanley
New York
$127M +$54.7M +166,347 +76%
William Blair Investment Management
14
William Blair Investment Management
Illinois
$117M -$6.12M -18,616 -5%
UBS Group
15
UBS Group
Switzerland
$106M -$1.24M -3,767 -1%
WP
16
Woodline Partners
California
$105M +$2.73M +8,316 +3%
Bank of America
17
Bank of America
North Carolina
$81.5M +$9.24M +28,133 +13%
HRCM
18
Hood River Capital Management
Florida
$80.8M +$38.2M +116,155 +91%
Pictet Asset Management
19
Pictet Asset Management
Switzerland
$68.5M -$473K -1,441 -0.7%
Adage Capital Partners
20
Adage Capital Partners
Massachusetts
$63.5M +$56.4M +171,649 +860%
Goldman Sachs
21
Goldman Sachs
New York
$62.8M -$13.7M -41,811 -18%
ACH
22
ArrowMark Colorado Holdings
Colorado
$59.7M -$6.43M -19,558 -10%
RSCM
23
Rock Springs Capital Management
Maryland
$55.2M -$32.4M -98,514 -37%
EAM
24
Erste Asset Management
Austria
$54.4M
American Century Companies
25
American Century Companies
Missouri
$52.4M +$7.05M +21,457 +16%