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Zymeworks
ZYME

Overview Fund Activity

178 hedge funds and large institutions have $942M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 30 closing their positions.

Holders
178
Holders Change
-5
Holders Change %
-2.73%
% of All Funds
2.39%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
53
Closed
30
Calls
$3.35M
Puts
$208K
Net Calls
+$3.14M
Net Calls Change
-$26K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
GIM
26
Granahan Investment Management
Massachusetts
$4.78M 380,783 -26,806 -7%
JAM
27
Jupiter Asset Management
United Kingdom
$4.64M 369,499 – –
Northern Trust
28
Northern Trust
Illinois
$4.39M 349,799 -37,124 -10%
SB
29
Samsara BioCapital
California
$3.89M 310,300 -356,367 -53%
SAM
30
Silvercrest Asset Management
New York
$3.52M 280,726 – –
D.E. Shaw & Co
31
D.E. Shaw & Co
New York
$3.2M 255,291 +192,192 +305%
UBS Group
32
UBS Group
Switzerland
$3.16M 251,510 +37,210 +17%
Citadel Advisors
33
Citadel Advisors
Florida
$3.09M 246,155 +65,485 +36%
PIM
34
Platinum Investment Management
Australia
$2.99M 238,391 -40,267 -14%
TI
35
Trexquant Investment
Connecticut
$2.77M 220,982 +173 +0.1%
OM
36
Opaleye Management
Massachusetts
$2.64M 210,000 +35,000 +20%
PMAM
37
Picton Mahoney Asset Management
Ontario, Canada
$2.61M 207,602 -427 -0.2%
HIM
38
Hillsdale Investment Management
Ontario, Canada
$2.57M 205,022 -31,903 -13%
Norges Bank
39
Norges Bank
Norway
$2.53M 201,700 +201,700 New
TC
40
Tejara Capital
United Kingdom
$2.51M 200,150 +10,741 +6%
Federated Hermes
41
Federated Hermes
Pennsylvania
$2.29M 182,270 +358 +0.2%
Wellington Management Group
42
Wellington Management Group
Massachusetts
$2.27M 180,690 -1,556 -0.9%
Axa
43
Axa
France
$2.2M 175,121 +175,121 New
Wells Fargo
44
Wells Fargo
California
$2.09M 166,428 +66,119 +66%
AQR Capital Management
45
AQR Capital Management
Connecticut
$2.09M 166,143 +117,658 +243%
Citigroup
46
Citigroup
New York
$1.96M 155,998 +114,800 +279%
Squarepoint
47
Squarepoint
New York
$1.95M 155,599 +91,997 +145%
KCM
48
Kennedy Capital Management
Missouri
$1.84M 146,954 +10,635 +8%
Bank of New York Mellon
49
Bank of New York Mellon
New York
$1.67M 133,090 +12,363 +10%
Raymond James Financial
50
Raymond James Financial
Florida
$1.56M 124,435 +7,724 +7%
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