Jane Street
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Jane Street’s Zymeworks ZYME Stock Holding History

Jane Street’s Portfolio ZYME Stock Details ZYME Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$5.68M Buy
226,967
+156,522
+222% +$3.7M ﹤0.01% 3323
2025
Q4 		$1.85M Sell
70,445
-74,761
-51% -$1.63M ﹤0.01% 4954
2025
Q3 		$2.48M Buy
145,206
+132,657
+1,057% +$1.9M ﹤0.01% 4541
2025
Q2 		$157K Sell
12,549
-123,214
-91% -$1.47M ﹤0.01% 8711
2025
Q1 		$1.62M Buy
135,763
+112,636
+487% +$1.54M ﹤0.01% 4711
2024
Q4 		$339K Sell
23,127
-57,199
-71% -$800K ﹤0.01% 7532
2024
Q3 		$1.01M Buy
80,326
+17,205
+27% +$187K ﹤0.01% 5872
2024
Q2 		$537K Buy
63,121
+27,056
+75% +$241K ﹤0.01% 6901
2024
Q1 		$379K Sell
36,065
-10,705
-23% -$119K ﹤0.01% 7168
2023
Q4 		$486K Buy
+46,770
New +$373K ﹤0.01% 6807
2023
Q2 		– Sell
-140,816
Closed -$1.27M – 9709
2023
Q1 		$1.27M Buy
+140,816
New +$1.23M ﹤0.01% 4575
2022
Q4 		– Sell
-36,572
Closed -$225K – 10302
2022
Q3 		$225K Sell
36,572
-34,692
-49% -$209K ﹤0.01% 7997
2022
Q2 		$378K Buy
71,264
+47,442
+199% +$287K ﹤0.01% 7220
2022
Q1 		$156K Buy
23,822
+8,032
+51% +$71.6K ﹤0.01% 9202
2021
Q4 		$259K Buy
15,790
+944
+6% +$19.7K ﹤0.01% 8430
2021
Q3 		$431K Buy
14,846
+3,840
+35% +$128K ﹤0.01% 7563
2021
Q2 		$382K Buy
11,006
+2,602
+31% +$82.5K ﹤0.01% 7751
2021
Q1 		$265K Buy
+8,404
New +$342K ﹤0.01% 7873
2020
Q4 		– Sell
-18,333
Closed -$851K – 8223
2020
Q3 		$854K Buy
+18,333
New +$629K ﹤0.01% 4356
2020
Q2 		– Sell
-11,611
Closed -$428K – 7662
2020
Q1 		$412K Buy
+11,611
New +$475K ﹤0.01% 3853
2019
Q3 		– Sell
-9,593
Closed -$211K – 5875
2019
Q2 		$211K Buy
+9,593
New +$176K ﹤0.01% 4634
2019
Q1 		– Sell
-76,803
Closed -$1.13M – 5748
2018
Q4 		$1.13M Buy
+76,803
New +$1.01M ﹤0.01% 2393

Other funds holding ZYME

EC
EcoR1 Capital San Francisco, California $2.36B AUM 204.53% 1-Year Est. Return
RCMNY
Rubric Capital Management (New York) New York $9.44B AUM 68.42% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
PA
Perceptive Advisors New York $5.12B AUM 314.02% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
BNP Paribas Asset Management
BNP Paribas Asset Management Paris, France $86.1B AUM 29.11% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Citadel Advisors
Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return
Dimensional Fund Advisors
Dimensional Fund Advisors Austin, Texas $481B AUM 30.42% 1-Year Est. Return

Jane Street's ZYME Position: Q1 2026 in Review

Jane Street increased its Zymeworks (ZYME) stake by 222% in Q1 2026, buying an estimated $3.7M and bringing the position to 226,967 shares worth $5.68M. The position accounts for ﹤0.01% of the portfolio, ranked #3323.

Jane Street first reported a position in ZYME in Q4 2018 and has held it in 22 quarters since. 211 funds tracked by Wall St. Rank hold ZYME as of Q1 2026.

  • Jane Street held 226,967 shares of Zymeworks worth $5.68M as of Q1 2026.
  • Jane Street bought 156,522 Zymeworks shares in Q1 2026, an estimated $3.7M.
  • Zymeworks made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #3323 holding.
  • Jane Street first reported a position in Zymeworks in Q4 2018 and has held it in 22 quarters since.
  • 211 funds tracked by Wall St. Rank held Zymeworks as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.