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Zymeworks
ZYME

Overview Fund Activity

178 hedge funds and large institutions have $942M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 53 reducing their positions, and 30 closing their positions.

Holders
178
Holders Change
-5
Holders Change %
-2.73%
% of All Funds
2.39%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
53
Closed
30
Calls
$3.35M
Puts
$208K
Net Calls
+$3.14M
Net Calls Change
-$26K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Market Value Shares Shares
Change 		Shares
Change %
Legal & General Group
76
Legal & General Group
United Kingdom
$549K 43,763 -3,027 -6%
California State Teachers Retirement System (CalSTRS)
77
California State Teachers Retirement System (CalSTRS)
California
$538K 42,873 -910 -2%
OSAM
78
O'Shaughnessy Asset Management
Connecticut
$517K 41,224 -55,105 -57%
HSBC Holdings
79
HSBC Holdings
United Kingdom
$461K 36,497 +36,497 New
Man Group
80
Man Group
United Kingdom
$444K 35,406 +24,547 +226%
Victory Capital Management
81
Victory Capital Management
Texas
$434K 34,610 -9,660 -22%
Tudor Investment Corp
82
Tudor Investment Corp
Connecticut
$430K 34,293 +34,293 New
PAM
83
Panagora Asset Management
Massachusetts
$421K 33,559 +33,559 New
MIM
84
MetLife Investment Management
New Jersey
$418K 33,309 – –
HF
85
HRT Financial
New York
$411K 32,758 -32,622 -50%
Commonwealth Equity Services
86
Commonwealth Equity Services
Massachusetts
$404K 32,170 -5,472 -15%
American Century Companies
87
American Century Companies
Missouri
$391K 31,147 – –
XT
88
XTX Topco
Cayman Islands
$389K 31,021 +10,816 +54%
Zurich Cantonal Bank
89
Zurich Cantonal Bank
Switzerland
$376K 29,934 +5,403 +22%
JSW
90
Journey Strategic Wealth
New Jersey
$364K 29,040 +99 +0.3%
Russell Investments Group
91
Russell Investments Group
United Kingdom
$355K 28,312 +25,259 +827%
Bank of Montreal
92
Bank of Montreal
Ontario, Canada
$347K 27,642 +1,730 +7%
Massachusetts Financial Services
93
Massachusetts Financial Services
Massachusetts
$340K 27,109 +334 +1%
Mirae Asset Global ETFs Holdings
94
Mirae Asset Global ETFs Holdings
Hong Kong
$337K 26,863 -5,522 -17%
T. Rowe Price Associates
95
T. Rowe Price Associates
Maryland
$337K 26,816 +2,703 +11%
LCM
96
Landscape Capital Management
New Jersey
$335K 26,667 +26,667 New
Creative Planning
97
Creative Planning
Kansas
$319K 25,389 +13,567 +115%
RWM
98
Ritholtz Wealth Management
New York
$317K 25,235 -35,259 -58%
IC
99
Ikarian Capital
Texas
$314K 25,000 +25,000 New
IIM
100
INTECH Investment Management
Florida
$291K 23,163 -17,100 -42%
2 3
4
5 6