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Zymeworks
ZYME

Overview Fund Activity

180 hedge funds and large institutions have $949M invested in Zymeworks in 2025 Q2 according to their latest regulatory filings, with 29 funds opening new positions, 62 increasing their positions, 55 reducing their positions, and 30 closing their positions.

Holders
180
Holders Change
-3
Holders Change %
-1.64%
% of All Funds
2.42%
Holding in Top 10
5
Holding in Top 10 Change
–
Holding in Top 10 Change %
–
% of All Funds
0.07%
New
29
Increased
62
Reduced
55
Closed
30
Calls
$4.2M
Puts
$883K
Net Calls
+$3.32M
Net Calls Change
+$154K

Top Buyers

1
EC
1
EcoR1 Capital
California
$288M
2
Vanguard Group
2
Vanguard Group
Pennsylvania
$30.9M
3
VPC
3
Vestal Point Capital
New York
$14.4M
4
Adage Capital Partners
4
Adage Capital Partners
Massachusetts
$5.97M
5
NL
5
Nuveen LLC
North Carolina
$8.22M

Top Sellers

1
UBS AM
1
UBS AM
Illinois
$30.9M
2
BCM
2
Bridgeway Capital Management
Texas
$0
3
RG
3
Redmile Group
California
$52.1M
4
PA
4
Perceptive Advisors
New York
$16M
5
FCM
5
Farallon Capital Management
California
$0
Name Holding Trade Value Shares
Change 		Shares
Change %
ASRS
126
Arizona State Retirement System
Arizona
$140K -$8.62K -687 -6%
BHCM
127
Brevan Howard Capital Management
Jersey
$133K +$133K +10,628 New
JIR
128
James Investment Research
Ohio
$133K – – –
Teacher Retirement System of Texas
129
Teacher Retirement System of Texas
Texas
$130K -$10K -800 -7%
BNP Paribas Financial Markets
130
BNP Paribas Financial Markets
France
$129K +$79.2K +6,307 +158%
TFA
131
TPG Financial Advisors
Oregon
$126K – – –
NEI
132
Northwest & Ethical Investments
Ontario, Canada
$125K – – –
SAM
133
Shell Asset Management
Netherlands
$117K -$35.3K -2,805 -23%
SG Americas Securities
134
SG Americas Securities
New York
$109K -$1.12M -89,494 -91%
Carson Wealth (CWM LLC)
135
Carson Wealth (CWM LLC)
Nebraska
$108K +$79K +6,271 +273%
KK
136
KLP Kapitalforvaltning
Norway
$91.6K -$37.7K -3,000 -29%
VIA
137
Virtus Investment Advisers
Connecticut
$90.1K -$73.1K -5,828 -45%
Simplex Trading
138
Simplex Trading
Illinois
$80K +$28.3K +2,277 +55%
PAS
139
Point72 Asia (Singapore)
Singapore
$79.2K +$79.2K +6,311 New
AIP
140
Ameritas Investment Partners
Nebraska
$70.5K – – –
CA
141
Clearstead Advisors
Ohio
$62.8K – – –
TRCT
142
Tower Research Capital (TRC)
New York
$62.1K +$14.2K +1,131 +30%
DekaBank Deutsche Girozentrale
143
DekaBank Deutsche Girozentrale
Germany
$48K – – –
Fidelity Investments
144
Fidelity Investments
Massachusetts
$39K -$122K -9,720 -76%
Mirae Asset Global Investments
145
Mirae Asset Global Investments
South Korea
$33.8K +$4.54K +362 +16%
AB
146
Amalgamated Bank
New York
$24K – – –
GFM
147
GF Fund Management
China
$22.1K – – –
Nisa Investment Advisors
148
Nisa Investment Advisors
Missouri
$12.1K +$7.98K +636 +192%
FDCDDQ
149
Federation des caisses Desjardins du Quebec
Quebec, Canada
$10.9K – – –
GI
150
GAMMA Investing
California
$10.2K +$3.35K +267 +49%
4 5
6
7 8